Project: Role of cytokines in the pathogenicity of avian influenza viruses for poultry and humans
- project duration
- 01-FEB-05 – 31-JUL-08
- This research aims to examine whether an overproduction of proinflammatory cytokines mediates the extreme pathogenicity of so-called highly pathogenic avian influenza viruses for poultry and for mammals. Experimental infections of chickens and pigs with highly and low pathogenic influenza viruses will be performed, the virus tissue distribution and cytokine profile will be compared.