Ghent University Academic Bibliography


Project: Identification and Functional Analysis of Candidate MYCN Transcriptional Target Genes and Molecular Delineation of the 11q13 Amplicon in Neuroblastoma

project duration
01-OCT-02 – 31-DEC-06
Neuroblastoma is the most frequent extracranial solid tumour in children. Despite the existence of multimodal treatments, the prognosis of most patients remains unfavourable. A subgroup of aggressive neuroblastoma tumours is characterised by amplification of the MYCN transcription factor. The identification of new MYCN target genes could result in improved treatment stategies.