Project: Radionuclide therapy of the second generation for treatment of hepatocellular carcinoma (HCC).
- project duration
- 01-OCT-01 – 30-SEP-03
- To optimise radionuclide therapy for HCC with Lipiodol: An in vitro comparison of the effects of Iodine-131-Lipiodol, Rhenium-188-Lipiodol and the combination with radiosensitizers,will be performed on multicellular tumour spheroids. The stability, biodistribution and effect of Rhenium-188-Lipiodol and the radiosensitizers will be tested in a tumour bearing animal model. Finally rhenium-188-Lipiodol and radiosensitizers will be introduced in a clinical trial.