Project: Influence of phages on the microbial ecology of the gastro-intestinal system

project duration: 01-OCT-03 – 30-SEP-05
abstract: The appelication of baceriophages against an intestinal infection with Enterobacter aerogenes by means of a Simulation of the Human gastro-intestial microbial Ecosystem (SHIME). The effect on the microbial community is monitored by 16S rDNA PCR-DGGE analysis. The dynamics of phage replication and resulting bacterial lysis in the SHIME is studied by flowcytometry.