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Project: Influence of physiological and pathological factors on the enantioselective disposition of drugs.

project duration
01-JAN-00 – 31-DEC-99
abstract
It is our aim to study the stereoselectivity of the plasma and tissue binding, the metabolism the pharmacokinetics and the pharmacological effect of some racemic drugs. The influence of physiological and pathological factors, such as inflammation, renal failure, liver disease, age, pregnance thereupon will be studied. This study will be done partly in humans and partly in animals.