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Project: Analytics and metabolisation studies of endocrine disrupters ((semi-) natural hormones, xenobiotics and phytosterols) in the invertebrate Neomysis integer by mass spectrometry

01-JAN-04 – 31-OCT-06

The metabolisation of various natural hormones, xenobiotics and phytosterols is investigated in the aquatic invertebrate Neomysis integer. Analytical procedures for identification, quantification and purification of the different metabolites are established with LC-MSn and/or GC-MSn. Comparative metabolisation studies are undertaken and the possibilities of producing standards in vivo are explored.