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Project: Identification of protective antigens in the ES thiol fraction of Ostertagia ostertagi

project duration
01-JAN-05 – 31-OCT-09
abstract
Aspartyl protease inhibitor (ASP) and cysteine proteases will be isolated from the protective ES-thiol fraction of the abomasal nematode Ostertagia ostertagi. Calves will be immunised with the purified proteins to evaluate their protective capacities. Protective antigens will be expressed as recombinant proteins in Caenorhabditis elegans. Calves will be immunised with the recombinant proteins to evaluate their protective capacities.