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Project: Analysis of gastrointestinal mucosal immuneresponses in the pig.

01-JAN-00 – 31-DEC-99

Immunostimulating and -suppressive mechanisms will be activated at the gastrointestinal mucosa by infecting pigs with F4+ enterotoxigenic E.coli or the gastric parasite Hyostrongylus rubidus or by oral immunisation with the F4 antigen.The role of different T-lymphocyte subpopulations in the immune mechanisms will be analysed. Recombinant antigens of H.rubidus will be screened for their immuno-stimulating potential.