Project: Organisation of the nucleus in relation to cell proliferation and DNA repair systems after ionizing radiation.
- project duration
- 01-JAN-99 – 31-OCT-01
- The aim of this project is to study the effects of ionizing radiation on different cell lines (SKBR3 and HeLa), as well as on specific transgenic cell lines with varying telomere length. Different techniques will be applied to determine survival of the cells and the level of expression of specific proteins (RAD51 and BRCA1) in vitro. The extent to which the expression is modulated by senescence and apoptosis will also be studied.