Project: Investigations of biochemical and metabolic disturbances following uremic retention in chronic renal failure.
- project duration
- 01-JAN-97 – 31-OCT-01
- Chronic renal failure is characterized by the retention of uremic metabolites. They are responsible for the deterioration of various biochemical and metabolic functions. Our research will especially focus on the identification of the re sponsible compounds for the following disturbances : phagocyte dysfunction, disturbances of the calcitriol metabolism, cellular A1-uptake and Ca-efflux, alterations in adhesion of T-lymphocytes, protein binding of drugs.