Project: Activation and expression of NFkB in chronic lymphatic leukemia in correlation with in vitro apoptosis and clinical relevance.
01-JAN-99 – 31-OCT-02
The purpose of the study is to examine the correlation of in vitro resistance of CLL cells to therapy with clinical resistance and other prognostic factors. A relationship with the type of NFkB and the presence of constitutive active NFkB will be explored. If such a relationship is found, it will be examined if pharmacological modification of the FNkB mediated resistance is possible.