Project: NMR study of the interplay between structure and dynamics in actin binding Headpiece domains and Profilin isoforms
- project duration
- 01-JAN-04 – 31-OCT-08
- This research project aims at providing insight in the structural and dynamic determinants that are involved in two different classes of actin binding proteins: Headpiece domains from the C-terminal part of otherwise unrelated multidomain proteins, and the Profilin isoforms I, Iia and Iib. This is achieved b combining multidimensional and multinuclear NMR spectroscopic techniques with molecular biology and biophysical methods.