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Project: Cysteine-proteinases as putative antigens for vaccination of calves against Ostertagia ostertagi.

project duration
01-JAN-99 – 31-OCT-01
abstract
The aim of this project is to evaluate cysteine-proteinases, excreted/secreted by the abomasal nematode Ostertagia ostertagi as putative antigens for vaccination of calves against this parasite. The research includes in vitro production of excretion/secretion (ES) products by L4 larvae and adult Ostertagia, characterisation and purification of proteinases from ES material, and evaluation of the protective capacities of purified cysteine-proteinases against Ostertagia in a vaccination trial.