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Project: Identification by mass spectrometry of LTBR dependant differentiation factors important in the development of natural killer T lymphocytes

project duration
01-JAN-03 – 31-OCT-05
abstract
The aim of this project is the identificaiton of new differentiation factors for NKT cells in a mice model. Based on the observation that LTBR mediated signalling is essential for the development and/or differentiation of NKT cells, we will investigate which specific growth factors are expressed and/or secreted by mouse embryonic fibroblasts upon stimulation with an anit-LTBR monoclonal antibody.