Academic Bibliography

Search 200 years of publications by Ghent University researchers.

dr. Mark Gontsarik

Faculty of Pharmaceutical Sciences > Department of Pharmaceutical analysis

ORCID iD: 0000-0001-7613-5137

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Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

Yong Chen (UGent) , Emily De Lombaerde, Aimee-Rose Bugler-Lamb (UGent) , Zifu Zhong (UGent) , Martijn Schuijs (UGent) , Claudia Mariela Brenis Gómez (UGent) , Jamie De Baere (UGent) , Mark Gontsarik (UGent) , Heleen Lauwers (UGent) , Kim Deswarte (UGent) , et al.

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 64(28).
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A f entanyl hapten-displaying lipid nanoparticle vaccine that non-covalently encapsulates a TLR7/8 agonist and T-helper epitope induces protective anti-fentanyl immunity

Zifu Zhong (UGent) , Marie Deventer (UGent) , Yong Chen (UGent) , Stijn Vanhee (UGent) , Inés Lammens (UGent) , Kim Deswarte (UGent) , Yi Huang (UGent) , Tingting Ye, Haixiu Wang, Lutz Nuhn, et al.

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 64(7).
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CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity

Tingting Ye, Zifu Zhong (UGent) , Federica Cappellesso, Kim Deswarte (UGent) , Yong Chen (UGent) , Heleen Lauwers (UGent) , Emily De Lombaerde, Mark Gontsarik (UGent) , Stefan Lienenklaus, Dorien Van Lysebetten, et al.

(2024) BIOMATERIALS. 311.
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Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids

Alexander Lamoot, Joris Lammens (UGent) , Emily De Lombaerde, Zifu Zhong (UGent) , Mark Gontsarik (UGent) , Yong Chen (UGent) , Thomas De Beer (UGent) and Bruno De Geest (UGent)

(2023) BIOMATERIALS SCIENCE. 11(12). p.4327-4334
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Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue

Zifu Zhong (UGent) , Yong Chen (UGent) , Kim Deswarte (UGent) , Heleen Lauwers (UGent) , Emily De Lombaerde, Xiaole Cui (UGent) , Simon Van Herck (UGent) , Tingting Ye, Mark Gontsarik (UGent) , Stefan Lienenklaus, et al.

(2023) ADVANCED HEALTHCARE MATERIALS. 12(32).