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Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development
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- Journal Article
- A1
- open access
ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms
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- Journal Article
- A1
- open access
GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate
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- Journal Article
- A1
- open access
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling
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- Journal Article
- A1
- open access
Notch3 activation is sufficient but not required for inducing human T-lineage specification
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Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength
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Notch ligands control the human alpha beta/gamma delta lineage choice through receptor-specific induction of differential Notch signal strength
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- Journal Article
- A1
- open access
cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)
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Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern