prof. dr. Koen Venken
- ORCID iD
- 0000-0002-4950-386X
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Tregs protect against invariant NKT cell-mediated autoimmune colitis and hepatitis
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Gut inflammation in axial spondyloarthritis patients is characterized by a marked type 17 skewed mucosal innate‐like T cell signature
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- Journal Article
- A1
- open access
Distinct immune modulatory roles of regulatory T cells in gut versus joint inflammation in TNF-driven spondyloarthritis
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- Journal Article
- A1
- open access
ROR gamma t inhibition ameliorates IL-23 driven experimental psoriatic arthritis by predominantly modulating gamma delta-T cells
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- Journal Article
- A1
- open access
In vitro triple coculture with gut microbiota from spondyloarthritis patients is characterized by inter-individual differences in inflammatory responses
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- Journal Article
- A1
- open access
Crossing the boundaries : IL-23 and its role in linking inflammation of the skin, gut and joints
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Intestinal microbiota, HLA-B27, and spondyloarthritis dangerous liaisons
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- Journal Article
- A1
- open access
ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids
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The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD
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- Journal Article
- A1
- open access
MAIT cells come to the rescue in cancer immunotherapy?
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Deletion of mucosa-associated lymphoid tissue lymphoma translocation protein 1 in mouse T cells protects against development of autoimmune arthritis but leads to spontaneous osteoporosis
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Running promotes chronicity of arthritis by local modulation of complement activators and impairing T regulatory feedback loops
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- Journal Article
- A1
- open access
RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients
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4''-O-Alkylated α-galactosylceramide analogues as iNKT-cell antigens : synthetic, biological, and structural studies
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- Journal Article
- A1
- open access
Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70
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- Journal Article
- A1
- open access
It takes 'guts' to cause joint inflammation : role of innate-like T cells
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Checkpoint inhibition in the treatment of multiple myeloma : a way to boost innate-like T cell anti-tumor function?
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The role of the microbiome in gut and joint inflammation in psoriatic arthritis and spondyloarthritis
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- Conference Paper
- C3
- open access
4"-O-alkylated α-galactosylceramide analogues as iNKT cell antigens : synthetic, biological and structural studies
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A novel LPS-responsive beige-like anchor protein (LRBA) mutation presents with normal cytotoxic T lymphocyte-associated protein 4 (CTLA-4) and overactive TH17 immunity
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- Journal Article
- A1
- open access
Both mucosal-associated invariant and natural killer T-cell deficiency in multiple myeloma can be countered by PD-1 inhibition
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Leptin receptor antagonism of iNKT cell function : a novel strategy to combat multiple myeloma
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Synthesis of C6′′-modified α-C-GalCer analogues as mouse and human iNKT cell agonists
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- Journal Article
- A1
- open access
Efficient divergent synthesis of new immunostimulant 4″-modified α-galactosylceramide analogues
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- Journal Article
- A1
- open access
Does an NKT-cell-based immunotherapeutic approach have a future in multiple myeloma?
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New immune cells in spondyloarthritis: key players or innocent bystanders?
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IL-23 Responsive innate-like T cells in spondyloarthritis: the less frequent they are, the more vital they appear
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- Journal Article
- A1
- open access
Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level
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A bidirectional crosstalk between iNKT cells and adipocytes mediated by leptin modulates susceptibility for T cell mediated hepatitis
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- Journal Article
- A1
- open access
An in silico approach for modelling T-helper polarizing iNKT cell agonists
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Senescence marker killer cell lectin-like receptor G1 (KLRG1) contributes to TNF-α production by interaction with its soluble E-cadherin ligand in chronically inflamed joints
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Bacterial CD1d-restricted glycolipids induce IL-10 production by human regulatory T cells upon cross-talk with invariant NKT cells
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- Journal Article
- A1
- open access
Enhanced TCR footprint by a novel glycolipid increases NKT-dependent tumor protection
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- Conference Paper
- C3
- open access
A computational high-throughput screening approach of iNKT-agonists: a novel tool to find optimized iNKT cell ligands
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Elevated soluble E-cadherin levels in chronically inflamed joints favour TNF production by KLRG1 expressing T cells
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Elevated soluble E-cadherin levels in chronically inflamed joints favour TNF production by KLRG1 expressing T cells
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Synovial fluid derived iNKT cells in chronic arthritides show an increased PROGRAMMED DEATH-1 expression and anergic phenotype
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- Journal Article
- A1
- open access
Natural killer T cells in adipose tissue prevent insulin resistance
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Mechanisms regulating TNF-driven gut and joint inflammation
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Galactose modified iNKT cell agonists stabilised by a novel structural modification of CD1D lead to marked TH1 polarisation in vivo
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Intrarectal administration of oxygenated perfluorodecalin promotes healing of murine colitis by targeting inflammatory hypoxia
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Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis
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Memory CD4+CD127high T cells from patients with multiple sclerosis produce IL-17 in response to myelin antigens
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Haplotype 4 of the multiple sclerosis-associated interleukin-7 receptor alpha gene influences the frequency of recent thymic emigrants
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Disturbed regulatory T cell homeostasis in multiple sclerosis
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Optimizing the iNKT cell dependent antitumor effect using an altered glycolipid
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Optimizing the iNKT cell dependent antitumor effect using an altered glycolipid
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Suppression of human natural killer T cell function by CD4(+)CD25(+)FOXP3(+) regulatory T cells
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Invariant natural killer T cells are natural regulators of murine spondylarthritis
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Involvement of T-cell receptor-beta alterations in the development of otosclerosis linked to OTSC2
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A single nucleotide polymorphism within the interleukin-7 receptor alpha promoter influences recent thymic emigrants in multiple sclerosis
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Compromised CD4+ CD25high regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level
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Natural naive regulatory T cell development and function are disturbed in multiple sclerosis patients
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Natural naive regulatory T cell development and function are disturbed in multiple sclerosis patients
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Natural naive CD4+CD25+CD127low regulatory T cell (Treg) development and function are disturbed in multiple sclerosis patients: recovery of memory Treg homeostasis during disease progression
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Analyses of immunosenescent markers in patients with autoimmune disease
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A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses
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CD4+CD28null T cells in autoimmune disease: pathogenic features and decreased susceptibility to immunoregulation
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Reduced number of blood circulating foxp3+CD25highCD4+regulatory T cells and a decreased foxp3 expression at the single-cell level in patients with relapsing-remitting multiple sclerosis
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Compromised CD4+CD25Hi regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3 positive cells and a reduced FOXP3 expression at the single-cell level
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Effects of IFN-β, leptin and simvastatin on LIF secretion by T lymphocytes of MS patients and healthy controls
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Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression
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The role of CD4(+)CD28(null) T cells in autoimmune diseases
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Effects of IFN-beta, leptin and sinivastatin on LIF secretion by T lymphocytes of MS patients and healthy controls
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Secondary progressive in contrast to relapsing: remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T cell function and FOXP3 expression
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Impaired suppressive capacity and reduced FOXP3 expression of CD4+CD25+ regulatory T cells isolated from multiple sclerosis patients