Kim Deswarte

Journal Article
A1
open access

Maternal allergy and neonatal RSV infection synergize via FcR-mediated allergen uptake to promote the development of asthma in early life

Elisabeth De Leeuw (UGent) , Josefine F. Justesen, Cedric Bosteels (UGent) , Nincy Debeuf (UGent) , Manon Vanheerswynghels (UGent) , Leander Jonckheere (UGent) , Caroline De Wolf (UGent) , Alysia Wayenberg (UGent) , Karel Van Damme (UGent) , Stijn Vanhee (UGent) , et al.

(2025) SCIENCE IMMUNOLOGY. 10(113).

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A1
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Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

Yong Chen (UGent) , Emily De Lombaerde, Aimee-Rose Bugler-Lamb (UGent) , Zifu Zhong (UGent) , Martijn Schuijs (UGent) , Claudia Mariela Brenis Gómez (UGent) , Jamie De Baere (UGent) , Mark Gontsarik (UGent) , Heleen Lauwers (UGent) , Kim Deswarte (UGent) , et al.

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 64(28).

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A fentanyl hapten-displaying lipid nanoparticle vaccine that non-covalently encapsulates a TLR7/8 agonist and T-helper epitope induces protective anti-fentanyl immunity

Zifu Zhong (UGent) , Marie Deventer (UGent) , Yong Chen (UGent) , Stijn Vanhee (UGent) , Inés Lammens (UGent) , Kim Deswarte (UGent) , Yi Huang (UGent) , Tingting Ye, Haixiu Wang, Lutz Nuhn (UGent) , et al.

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 64(7).

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Galloyl dialkyl lipids drive encapsulation of peptides into lipid nanoparticles by hydrogen bonding

Tingting Ye, Yong Chen (UGent) , Zifu Zhong (UGent) , Yi Huang (UGent) , Jamie De Baere (UGent) , Mark Gontsarik (UGent) , Kim Deswarte (UGent) , Bianka Golba, Martijn Risseeuw (UGent) , Serge Van Calenbergh (UGent) , et al.

(2024) JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 147(1). p.1307-1318

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Miscellaneous
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The unfolded protein sensor IRE1a is essential for homeostatic dendritic cell maturation

Sophie Janssens (UGent) , Victor Bosteels, Sandra Maréchal (UGent) , Eva Cloots (UGent) , Laurien Van Heddegem, Simon Tavernier (UGent) , Sofie Rennen (UGent) , Clint De Nolf (UGent) , Seraja Amstelveen (UGent) , Jonathan Maelfait (UGent) , et al.

(2024) Research Square.

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CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity

Tingting Ye, Zifu Zhong (UGent) , Federica Cappellesso, Kim Deswarte (UGent) , Yong Chen (UGent) , Heleen Lauwers (UGent) , Emily De Lombaerde, Mark Gontsarik (UGent) , Stefan Lienenklaus, Dorien Van Lysebetten, et al.

(2024) BIOMATERIALS. 311.

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PH-triggered, lymph node focused immunodrug release by polymeric 2-propionic-3-methyl-maleic anhydrides with cholesteryl end groups

Alina G. Heck, Carolina Medina-Montano, Zifu Zhong (UGent) , Kim Deswarte (UGent) , Katharina Eigen, Judith Stickdorn, Johannes Kockelmann, Maximilian Scherger, Niek Sanders (UGent) , Stefan Lienenklaus, et al.

(2024) ADVANCED HEALTHCARE MATERIALS. 13(32).

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Combinatorial screening of biscarbamate ionizable lipids identifies a low reactogenicity lipid for lipid nanoparticle mRNA delivery

Emily De Lombaerde, Yong Chen (UGent) , Tingting Ye, Julie Deckers (UGent) , Giulia Mencarelli, Kim Deswarte (UGent) , Heleen Lauwers (UGent) , Ruben De Coen (UGent) , Sabah Kasmi (UGent) , Sanne Bevers, et al.

(2024) ADVANCED FUNCTIONAL MATERIALS. 34(21). p.1-16

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Ym1 protein crystals promote type 2 immunity

Ines Heyndrickx (UGent) , Kim Deswarte (UGent) , Kenneth Verstraete (UGent) , Koen Verschueren (UGent) , Ursula Smole (UGent) , Helena Catharine Aegerter (UGent) , Ann Dansercoer (UGent) , Hamida Hammad (UGent) , Savvas Savvides (UGent) and Bart Lambrecht (UGent)

(2024) ELIFE. 12.

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Lipid nanoparticle encapsulation empowers poly(I:C) to activate cytoplasmic RLRs and thereby increases its adjuvanticity

Alexander Lamoot, Sonia Jangra, Gabriel Laghlali, Prajakta Warang, Gagandeep Singh, Lauren A. Chang, Seok‐Chan Park, Gagandeep Singh, Kim Deswarte (UGent) , Zifu Zhong (UGent) , et al.

(2024) SMALL. 20(10).

Academic Bibliography

Kim Deswarte

Maternal allergy and neonatal RSV infection synergize via FcR-mediated allergen uptake to promote the development of asthma in early life

Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

A fentanyl hapten-displaying lipid nanoparticle vaccine that non-covalently encapsulates a TLR7/8 agonist and T-helper epitope induces protective anti-fentanyl immunity

Galloyl dialkyl lipids drive encapsulation of peptides into lipid nanoparticles by hydrogen bonding

The unfolded protein sensor IRE1a is essential for homeostatic dendritic cell maturation

CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity

PH-triggered, lymph node focused immunodrug release by polymeric 2-propionic-3-methyl-maleic anhydrides with cholesteryl end groups

Combinatorial screening of biscarbamate ionizable lipids identifies a low reactogenicity lipid for lipid nanoparticle mRNA delivery

Ym1 protein crystals promote type 2 immunity

Lipid nanoparticle encapsulation empowers poly(I:C) to activate cytoplasmic RLRs and thereby increases its adjuvanticity

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