dr. ir. Stefaan De Koker

Journal Article
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Imidazoquinoline-conjugated degradable coacervate conjugate for local cancer immunotherapy

Hui Li, Simon Van Herck (UGent) , Yongjun Liu, Yanyun Hao, Xiaochu Ding, Lutz Nuhn, Zifu Zhong (UGent) , Francis Combes (UGent) , Niek Sanders (UGent) , Stefan Lienenklaus, et al.

(2020) ACS BIOMATERIALS SCIENCE & ENGINEERING. 6(9). p.4993-5000

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The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines Is determined by the route of administration

Lien Van Hoecke (UGent) , Kenny Roose (UGent) , Marlies Ballegeer (UGent) , Zifu Zhong (UGent) , Niek Sanders (UGent) , Stefaan De Koker (UGent) , Xavier Saelens (UGent) and Sandra Van Lint (UGent)

(2020) MOLECULAR THERAPY-NUCLEIC ACIDS. 22. p.373-381

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Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

Bo Lou, Ans De Beuckelaer (UGent) , George Dakwar (UGent) , Katrien Remaut (UGent) , Johan Grooten (UGent) , Kevin Braeckmans (UGent) , Bruno De Geest (UGent) , Enrico Mastrobattista, Stefaan De Koker (UGent) and Wim E. Hennink

(2018) JOURNAL OF CONTROLLED RELEASE. 284. p.73-83

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Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

Lutz Nuhn (UGent) , Lien Van Hoecke (UGent) , Kim Deswarte (UGent) , Bert Schepens (UGent) , Yupeng Li, Bart Lambrecht (UGent) , Stefaan De Koker (UGent) , Sunil A David, Xavier Saelens (UGent) and Bruno De Geest (UGent)

(2018) BIOMATERIALS. 178. p.643-651

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Lymph-node-targeted immune activation by engineered block copolymer amphiphiles-TLR7/8 agonist conjugates

Simon Van Herck (UGent) , Kim Deswarte (UGent) , Lutz Nuhn (UGent) , Zifu Zhong (UGent) , João Portela Catani (UGent) , Yupeng Li, Niek Sanders (UGent) , Stefan Lienenklaus, Stefaan De Koker (UGent) , Bart Lambrecht (UGent) , et al.

(2018) JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 140(43). p.14300-14307

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Nanoparticle-conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses

Lutz Nuhn (UGent) , Stefaan De Koker (UGent) , Sandra Van Lint (UGent) , Zifu Zhong (UGent) , João Portela Catani (UGent) , Francis Combes (UGent) , Kim Deswarte (UGent) , Yupeng Li, Bart Lambrecht (UGent) , Stefan Lienenklaus, et al.

(2018) ADVANCED MATERIALS. 30(45).

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Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes

Lien Van Hoecke (UGent) , Sandra Van Lint (UGent) , Kenny Roose (UGent) , Alexander Van Parys (UGent) , Peter Vandenabeele (UGent) , Johan Grooten (UGent) , Jan Tavernier (UGent) , Stefaan De Koker (UGent) and Xavier Saelens (UGent)

(2018) NATURE COMMUNICATIONS. 9.

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Delivering type I interferon to dendritic cells empowers tumor eradication and immune combination treatments

Anje Cauwels (UGent) , Sandra Van Lint (UGent) , Franciane Paul, Genevieve Garcin, Stefaan De Koker (UGent) , Alexander Van Parys (UGent) , Thomas Wüest (UGent) , Sarah Gerlo (UGent) , José Van Der Heyden (UGent) , Yan Bordat, et al.

(2018) CANCER RESEARCH. 78(2). p.463-474

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Species-specific immunity to Helicobacter suis

Iris Bosschem (UGent) , Bram Flahou (UGent) , Kim Van Deun (UGent) , Stefaan De Koker (UGent) , Jiri Volf (UGent) , Annemieke Smet (UGent) , Richard Ducatelle (UGent) , Bert Devriendt (UGent) and Freddy Haesebrouck (UGent)

(2017) HELICOBACTER. 22(3).

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Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12

Stefaan De Koker (UGent) , Lien Van Hoecke (UGent) , Ans De Beuckelaer (UGent) , Kenny Roose (UGent) , Kim Deswarte (UGent) , Monique Willart (UGent) , Pieter Bogaert (UGent) , Thomas Naessens (UGent) , Bruno De Geest (UGent) , Xavier Saelens (UGent) , et al.

(2017) SCIENTIFIC REPORTS. 7.

Academic Bibliography

dr. ir. Stefaan De Koker

Imidazoquinoline-conjugated degradable coacervate conjugate for local cancer immunotherapy

The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines Is determined by the route of administration

Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

Lymph-node-targeted immune activation by engineered block copolymer amphiphiles-TLR7/8 agonist conjugates

Nanoparticle-conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes

Delivering type I interferon to dendritic cells empowers tumor eradication and immune combination treatments

Species-specific immunity to Helicobacter suis

Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12

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