dr. ir. Hanne Van Gorp

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The autoinflammation-associated NLRC4<SUP>V341A</SUP> mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice

Elien Eeckhout (UGent) , Tomoko Asaoka (UGent) , Hanne Van Gorp (UGent) , Dieter Demon (UGent) , Charlotte Girard-Guyonvarc'h, Vanessa Andries (UGent) , Lars Vereecke (UGent) , Cem Gabay, Mohamed Lamkanfi (UGent) , Geert van Loo (UGent) , et al.

(2023) FRONTIERS IN IMMUNOLOGY. 14.

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Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever

Selina K. Jorch, Annika McNally, Philipp Berger, Jonas Wolf, Kim Kaiser, Andrian Chetrusca Covash, Stefanie Robeck, Isabell Pastau, Olesja Fehler, Saskia-L. Jauch-Speer, et al.

(2023) JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 152(1). p.230-243

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GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis

Dhruv Chauhan, Dieter Demon (UGent) , Lieselotte Vande Walle (UGent) , Oonagh Paerewijck (UGent) , Annalisa Zecchin, Leslie Bosseler, Karin Santoni, Remi Planes, Silvia Ribó Gené (UGent) , Amelie Fossoul (UGent) , et al.

(2022) EMBO REPORTS. 23(10).

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Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax

Filip Van Hauwermeiren (UGent) , Nina Van Opdenbosch (UGent) , Hanne Van Gorp (UGent) , Nathalia de Vasconcelos, Geert van Loo (UGent) , Peter Vandenabeele (UGent) , Thirumala-Devi Kanneganti and Mohamed Lamkanfi (UGent)

(2022) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 119(2).

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Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever

Hanne Van Gorp (UGent) , Linyan Huang (UGent) , Pedro Henrique Viana Saavedra (UGent) , Marnik Vuylsteke, Tomoko Asaoka (UGent) , Giusi Prencipe, Antonella Insalaco, Benson Ogunjimi, Jerold Jeyaratnam, Ilaria Cataldo, et al.

(2020) ANNALS OF THE RHEUMATIC DISEASES. 79(7). p.960-968

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An apoptotic caspase network safeguards cell death induction in pyroptotic macrophages

Nathalia Moraes de Vasconcelos (UGent) , Nina Van Opdenbosch (UGent) , Hanne Van Gorp (UGent) , Rosa Martin-Perez, Annalisa Zecchin, Peter Vandenabeele (UGent) and Mohamed Lamkanfi (UGent)

(2020) CELL REPORTS. 32(4).

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A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

Simon Tavernier (UGent) , V Athanasopoulos, PATRICK VERLOO (UGent) , G Behrens, Jens Staal (UGent) , Delfien Bogaert (UGent) , Leslie Naesens (UGent) , Marieke De Bruyne (UGent) , Sofie Van Gassen (UGent) , Eef Parthoens (UGent) , et al.

(2019) NATURE COMMUNICATIONS. 10.

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The emerging roles of inflammasome-dependent cytokines in cancer development

Hanne Van Gorp (UGent) and Mohamed Lamkanfi (UGent)

(2019) EMBO REPORTS. 20(6).

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Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

Emma Persson (UGent) , Kenneth Verstraete (UGent) , Ines Heyndrickx (UGent) , Elien Gevaert (UGent) , Helena Catharine Aegerter (UGent) , Jean-Michel Percier, Kim Deswarte (UGent) , Koen Verschueren (UGent) , Ann Dansercoer (UGent) , Delphine Gras, et al.

(2019) SCIENCE. 364(6442).

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Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

Nathalia Moraes de Vasconcelos (UGent) , Nina Van Opdenbosch (UGent) , Hanne Van Gorp (UGent) , Eef Parthoens (UGent) and Mohamed Lamkanfi (UGent)

(2019) CELL DEATH AND DIFFERENTIATION. 26(1). p.146-161

Academic Bibliography

dr. ir. Hanne Van Gorp

The autoinflammation-associated NLRC4<SUP>V341A</SUP> mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice

Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever

GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis

Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax

Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever

An apoptotic caspase network safeguards cell death induction in pyroptotic macrophages

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

The emerging roles of inflammasome-dependent cytokines in cancer development

Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

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