prof. Savvas Savvides

A recombinant antibody fragment directed to the thymic stromal lymphopoietin receptor (CRLF2) efficiently targets pediatric Philadelphia chromosome-like acute lymphoblastic leukemia

Sara M. A. Mohamed, Andreas Wohlmann, Peter Schofield, Keith C. S. Sia, Hannah McCalmont, Savvas Savvides (UGent) , Kenneth Verstraete (UGent) , Maria Kavallaris, Daniel Christ, Karl-Heinz Friedrich, et al.

(2021) INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 190. p.214-223

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Structural basis of cytokine-mediated activation of ALK family receptors

Steven De Munck, Mathias Provost (UGent) , Michiko Kurikawa, Ikuko Omori, Junko Mukohyama, Jan Félix (UGent) , Yehudi Bloch (UGent) , Omar Abdel-Wahab, J. Fernando Bazan, Akihide Yoshimi, et al.

(2021) NATURE. 600. p.143-147

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Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors

Lijun Song (UGent) , Romain Merceron (UGent) , Fabian Hulpia (UGent) , Ainhoa Lucia, Begona Gracia, Yanlin Jian, Martijn Risseeuw (UGent) , Toon Verstraelen (UGent) , Paul Cos, Jose A. Ainsa, et al.

(2021) EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 225.

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CRISPR-SID : identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping

Thomas Naert, Dieter Tulkens (UGent) , Tom Van Nieuwenhuysen (UGent) , Joanna Przybyl, Suzan Demuynck (UGent) , Matt van de Rijn, Mushriq Al-Jazrawe, Benjamin A. Alman, Paul Coucke (UGent) , Kim De Leeneer (UGent) , et al.

(2021) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 118(47).

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Miscellaneous

Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase

Kenneth Verstraete (UGent) , Koen Verschueren (UGent) , Ann Dansercoer (UGent) and Savvas Savvides (UGent)

(2021) NATURE STRUCTURAL & MOLECULAR BIOLOGY. 28(8). p.636-638

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Minimal epitope for Mannitou IgM on paucimannose-carrying glycoproteins.

Stefania Robakiewicz, Clarisse Bridot, Sonia Serna, Ana Gimeno, Begoña Echeverria, Sandra Delgado, Jérôme de Ruyck, Shubham Semwal, Diego Charro, Ann Dansercoer (UGent) , et al.

(2021) GLYCOBIOLOGY. 31(8). p.1005-1007

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Engineering and crystal structure of a monomeric FLT3 ligand variant

Erwin Pannecoucke (UGent) , Laurens Raes and Savvas Savvides (UGent)

(2021) ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS. 77. p.121-127

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Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy

Helena Catharine Aegerter (UGent) , Ursula Smole (UGent) , Ines Heyndrickx (UGent) , Kenneth Verstraete (UGent) , Savvas Savvides (UGent) , Hamida Hammad (UGent) and Bart Lambrecht (UGent)

(2021) CURRENT OPINION IN IMMUNOLOGY. 72. p.104-110

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Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

Klaas Yperman, Anna Papageorgiou, Romain Merceron (UGent) , Steven De Munck, Yehudi Bloch (UGent) , Dominique Eeckhout (UGent) , Qihang Jiang (UGent) , Pieter Tack (UGent) , Rosa Grigoryan, Thomas Evangelidis, et al.

(2021) NATURE COMMUNICATIONS. 12(1).

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Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting

Erwin Pannecoucke (UGent) , Maaike Van Trimpont (UGent) , Johan Desmet, Tim Pieters (UGent) , Lindy Reunes (UGent) , Lisa Demoen (UGent) , Marnik Vuylsteke, Stefan Loverix, Karen Vandenbroucke, Philippe Alard, et al.

(2021) SCIENCE ADVANCES. 7(13).

Academic Bibliography

prof. Savvas Savvides

A recombinant antibody fragment directed to the thymic stromal lymphopoietin receptor (CRLF2) efficiently targets pediatric Philadelphia chromosome-like acute lymphoblastic leukemia

Structural basis of cytokine-mediated activation of ALK family receptors

Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors

CRISPR-SID : identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping

Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase

Minimal epitope for Mannitou IgM on paucimannose-carrying glycoproteins.

Engineering and crystal structure of a monomeric FLT3 ligand variant

Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy

Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting

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