prof. dr. Bart Vandekerckhove

Journal Article
A2
open access

Preclinical toxicological assessment of an alpha-galactosylceramide-adjuvanted mRNA cancer vaccine in Wistar Han rats and domestic pigs

Sofie Meulewaeter (UGent) , Margo De Velder (UGent) , Diethard Reckelbus (UGent) , Kevin Mwangi (UGent) , Thomas Ehouarne (UGent) , Ilke Aernout (UGent) , Yanou Engelen (UGent) , Fëllanza Halimi (UGent) , Isis Van herteryck (UGent) , Lobke De Bels (UGent) , et al.

(2025) MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT.

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Journal Article
A1
open access

Photoporation of NK-92MI cells with biodegradable polydopamine nanosensitizers as a promising strategy for the generation of engineered NK cell therapies

Charlotte Hinnekens (UGent) , Aranit Harizaj (UGent) , Dominika Berdecka (UGent) , Ilke Aernout (UGent) , Molood Shariati (UGent) , Stefanie Peeters, Eva Lion, Stefaan De Smedt (UGent) , Bart Vandekerckhove (UGent) , Kevin Braeckmans (UGent) , et al.

(2024) APPLIED MATERIALS TODAY. 40.

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Journal Article
A1
open access

ThymoSpheres culture : a model to study human polyclonal unconventional T cells

Lore Billiet (UGent) , Hanne Jansen, Melissa Pille (UGent) , Lena Boehme (UGent) , Guillem Sanchez Sanchez, Laurenz De Cock (UGent) , Glenn Goetgeluk (UGent) , Eva Pascal (UGent) , Stijn De Munter (UGent) , Lucas Deseins (UGent) , et al.

(2024) EUROPEAN JOURNAL OF IMMUNOLOGY. 54(12).

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Journal Article
A1
open access

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline Ingels (UGent) , Laurenz De Cock (UGent) , Dieter Stevens (UGent) , Rupert Mayer (UGent) , Fabien Henri Thery (UGent) , Guillem Sanchez Sanchez, David Vermijlen, Karin Weening (UGent) , Saskia De Smet (UGent) , Nele Lootens (UGent) , et al.

(2024) CELL REPORTS MEDICINE. 5(5).

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Journal Article
A1
open access

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen-induced exhaustion

Stijn De Munter (UGent) , Juliane L. Buhl, Laurenz De Cock (UGent) , Alexander Van Parys (UGent) , Willem Daneels (UGent) , Eva Pascal (UGent) , Lucas Deseins (UGent) , Joline Ingels (UGent) , Glenn Goetgeluk (UGent) , Hanne Jansen, et al.

(2024) CANCER IMMUNOLOGY RESEARCH. 12(9). p.1236-1251

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Journal Article
A1
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HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells

Tamara De Vos (UGent) , Nicole Oatman (UGent) , Lena Boehme (UGent) , Tom Putteman (UGent) , Imke Velghe (UGent) , Yana Van Droogenbroeck (UGent) , Stijn De Munter (UGent) , Michaela Cesnekova (UGent) , Filip Van Nieuwerburgh (UGent) , Bart Vandekerckhove (UGent) , et al.

(2024) HAEMATOLOGICA. 109(11). p.3578-3592

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Journal Article
A1
open access

Gene editing-based targeted integration for correction of Wiskott-Aldrich syndrome

Melissa Pille (UGent) , John M. Avila, So Hyun Park, Cuong Q. Le, Haipeng Xue, Filomeen Haerynck (UGent) , Lavanya Saxena, Ciaran Lee, Elizabeth J. Shpall, Gang Bao, et al.

(2024) MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. 32(1).

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MIDRIXNEO-LUNG : safety and immunogenicity of a neoantigen-presenting autologous dendritic cell therapy in resected NSCLC patients

Joline Ingels (UGent) , Laurenz De Cock (UGent) , Dieter Stevens (UGent) , Karin Weening (UGent) , Veerle Surmont (UGent) , Jo Van Dorpe (UGent) , Francis Impens (UGent) , Björn Menten (UGent) , Karim Vermaelen (UGent) and Bart Vandekerckhove (UGent)

(2023) JOURNAL OF THORACIC ONCOLOGY. In Journal of Thoracic Oncology 18(11, Supplement). p.S526-S526

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Immunotherapy : towards engineered NK cell therapy : mRNA transfection of NK92 cells by photoporation with biodegradable polydopamine nanosensitizersHOTOPORATION WITH BIODEGRADABLE POLYDOPAMINE NANOSENSITIZERS

Charlotte Hinnekens (UGent) , Aranit Harizaj (UGent) , Ilia Goemaere (UGent) , Stefaan De Smedt (UGent) , Bart Vandekerckhove (UGent) , Juan Fraire (UGent) and Kevin Braeckmans (UGent)

(2023) CYTOTHERAPY. 25(6). p.S228-S228

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Journal Article
A1
open access

Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF

Kai Ling Liang (UGent) , Juliette Roels (UGent) , Marieke Lavaert, Tom Putteman (UGent) , Lena Boehme (UGent) , Laurentijn Tilleman (UGent) , Imke Velghe (UGent) , Valentina Pegoretti, Inge Van de Walle (UGent) , Stephanie Sontag, et al.

(2023) NATURE IMMUNOLOGY. 24(3). p.474-486

Academic Bibliography

prof. dr. Bart Vandekerckhove

Preclinical toxicological assessment of an alpha-galactosylceramide-adjuvanted mRNA cancer vaccine in Wistar Han rats and domestic pigs

Photoporation of NK-92MI cells with biodegradable polydopamine nanosensitizers as a promising strategy for the generation of engineered NK cell therapies

ThymoSpheres culture : a model to study human polyclonal unconventional T cells

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen-induced exhaustion

HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells

Gene editing-based targeted integration for correction of Wiskott-Aldrich syndrome

MIDRIXNEO-LUNG : safety and immunogenicity of a neoantigen-presenting autologous dendritic cell therapy in resected NSCLC patients

Immunotherapy : towards engineered NK cell therapy : mRNA transfection of NK92 cells by photoporation with biodegradable polydopamine nanosensitizersHOTOPORATION WITH BIODEGRADABLE POLYDOPAMINE NANOSENSITIZERS

Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF

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