prof. dr. Chris Verhofstede
- ORCID iD
- 0000-0002-0645-1174
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- Journal Article
- A1
- open access
Longitudinal patterns of inflammatory mediators after acute HIV infection correlate to intact and total reservoir
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- Journal Article
- A1
- open access
Towards novel HIV-1 serodiagnostic tests without vaccine-induced seroreactivity
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- Journal Article
- A1
- open access
Prevalence and evolution of transmitted human immunodeficiency virus drug resistance in Belgium between 2013 and 2019
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- Journal Article
- A1
- open access
Impact of COVID-19 on the Belgian HIV epidemic : slowdown of HIV transmission and testing and adaptation of care
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Screening algorithms for HBV, HCV, HIV and syphilis in an anatomical donation program
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Benefits of antiretroviral therapy initiation during acute HIV infection
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High frequency of new recombinant forms in HIV-1 transmission networks demonstrated by full genome sequencing
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Chronic and early antiretroviral therapy impact Human Immunodeficiency Virus (HIV) serological assay sensitivity, leading to more false-negative test results in HIV diagnosis
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- Journal Article
- A1
- open access
Piloting a surveillance system for HIV drug resistance in the European Union
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- Journal Article
- A1
- open access
Comparison of Sanger sequencing for hepatitis C virus genotyping with a commercial line probe assay in a tertiary hospital
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- Journal Article
- A1
- open access
Predominance of the heterozygous CCR5 delta‐24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface
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- Journal Article
- A1
- open access
Exploring HIV-1 transmission dynamics by combining phylogenetic analysis and infection timing
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- Journal Article
- A1
- open access
Single genome sequencing of near full-length HIV-1 RNA using a limiting dilution approach
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HIV rebound is predominantly fueled by genetically identical viral expansions from diverse reservoirs
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- Journal Article
- A1
- open access
Earlier initiation of antiretroviral treatment coincides with an initial control of the HIV-1 sub-subtype F1 outbreak among men-having-sex-with-men in Flanders, Belgium
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- Journal Article
- A1
- open access
Phylogenetic analysis of the Belgian HIV-1 epidemic reveals that local transmission is almost exclusively driven by men having sex with men despite presence of large African migrant communities
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- Journal Article
- A1
- open access
Quantification of total HIV-1 DNA in buffy coat cells, feasibility and potential added value for clinical follow-up of HIV-1 infected patients on ART
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- Journal Article
- A1
- open access
Frequency of occurrence of HIV-1 dual infection in a Belgian MSM population
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Meticulous plasma isolation is essential to avoid false low-level viraemia in Roche Cobas HIV-1 viral load assays
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- Journal Article
- A1
- open access
Decision tree for accurate infection timing in individuals newly diagnosed with HIV-1 infection
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- Journal Article
- A1
- open access
Longitudinal sequencing of HIV-1 infected patients with low-level viremia for years while on ART shows no indications for genetic evolution of the virus
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- Journal Article
- A1
- open access
Influence of chronic azithromycin treatment on the composition of the oropharyngeal microbial community in patients with severe asthma
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Deep sequencing of HIV-1 RNA and DNA in newly diagnosed patients with baseline drug resistance showed no indications for hidden resistance and is biased by strong interference of hypermutation
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- Journal Article
- A1
- open access
Late presentation to HIV testing is overestimated when based on the consensus definition
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Primary resistance to integrase strand-transfer inhibitors in Europe
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Drug resistance is rarely the cause or consequence of long-term persistent low-level viraemia in HIV-1-infected patients on ART
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- Journal Article
- A1
- open access
Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and mucosal reservoirs
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- Journal Article
- A1
- open access
Characteristics and spread to the native population of HIV-1 non-B subtypes in two European countries with high migration rate
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- Journal Article
- A1
- open access
Good continuum of HIV care in Belgium despite weaknesses in retention and linkage to care among migrants
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HIV-1 RNA and HIV-1 DNA persistence during suppressive ART with PI-based or nevirapine-based regimens
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Long-term early antiretroviral therapy limits the HIV-1 reservoir size as compared to later treatment initiation but not to levels found in long-term non-progressors
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- Journal Article
- A1
- open access
Comparison of methods for in-house screening of HLA*B57:01 to prevent abacavir hypersensitivity in HIV-1 care
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- Conference Paper
- C3
- open access
The impact of nevirapine- versus protease inhibitor-based regimens on virological markers of HIV-1 persistence during seemingly suppressive ART
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- Conference Paper
- C3
- open access
Factors associated with the continuum of care of HIV infected patients in Belgium
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Antiretrovirals for HIV prevention: when should they be recommended?
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Markers associated with persisting low-level viraemia under antiretroviral therapy in HIV-1 infection
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Determinants of adherence in a cohort of Belgian HIV patients: a pilot study
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Comparative performances of HIV-1 RNA load assays at low viral load levels: results of an international collaboration
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- Conference Paper
- C3
- open access
Touchdown digital PCR for quantification of difficult amplicons in the HIV genome
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Transmission network of an HIV type 1 strain with K103N in young Belgian patients from different risk groups
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- Journal Article
- A1
- open access
HIV-1 tropism determination using a phenotypic Env recombinant viral assay highlights overestimation of CXCR4-usage by genotypic prediction algorithms for CRRF01_AE and CRF02_AG
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Touchdown digital polymerase chain reaction for quantification of highly conserved sequences in the HIV-1 genome
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- Journal Article
- A1
- open access
Socio-economic, behavioural, (neuro)psychological and clinical determinants of HRQoL in people living with HIV: a pilot study
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- Journal Article
- A1
- open access
Frequency and predictors of HIV-1 co-receptor switch in treatment naive patients
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Polyfunctional CD4⁺ T cell responses in HIV-1 infected viral controllers compared with those in healthy recipients of an adjuvanted polyprotein HIV-1 vaccine
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- Conference Paper
- C3
- open access
Comprehensive characterization of LEDGF/p75 in a HIV-1 infected patient cohort
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- Conference Paper
- C3
- open access
Transmission of primary resistance mutation K103N in a cluster of Belgian young patients from different risk groups
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Correlation of coreceptor usage and disease progression
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- Journal Article
- A1
- open access
Characterization of LEDGF/p75 genetic variants and association with HIV-1 disease progression
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Ultra-deep sequencing of HIV-1 reverse transcriptase before start of an NNRTI-based regimen in treatment-naive patients
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Impact of triplicate testing on HIV genotypic tropism prediction in routine clinical practice
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Presence of CXCR4-using HIV-1 in patients with recently diagnosed infection: correlates and evidence for transmission
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- Conference Paper
- C3
- open access
Comprehensive characterization of LEDGF/p75 in a HIV-1-infected patient cohort
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Concordance between HIV-1 genotypic coreceptor tropism predictions based on plasma RNA and proviral DNA
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Association of haptoglobin phenotypes with the development of Kaposi's sarcoma in HIV patients
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European guidelines on the clinical management of HIV-1 tropism testing
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- Journal Article
- A1
- open access
Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment
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- Conference Paper
- C3
- open access
O121. Consensus statement of the European guidelines on clinical management of HIV-1 tropism testing
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- Journal Article
- A1
- open access
HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays
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Treatment intensification has no effect on the HIV-1 central nervous system infection in patients on suppressive antiretroviral therapy
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Comparison of the Generic HIV Viral Load® assay with the Amplicor™ HIV-1 Monitor v1.5 and Nuclisens HIV-1 EasyQ® v1.2 techniques for plasma HIV-1 RNA quantitation of non-B subtypes: the Kesho Bora preparatory study
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Viral load assay sensitivity and low level viremia in HAART treated HIV patients
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- Journal Article
- A1
- open access
Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections
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High prevalence of bevirimat resistance mutations in protease inhibitor-resistant HIV isolates
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Effect of triplicate testing on genotypic tropism prediction in routine clinical practice
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High prevalence of bevirimat resistance mutations in non-B subtypes and in PI-resistant HIV isolates
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Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients
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Comparison of population and 454 genotyping and Trofile phenotyping for tropism determination in patients selected for maraviroc initiation
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Population and clonal tropism phenotyping of clinical isolates and comparison with next generation sequencing and prediction tools
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- Journal Article
- A2
- open access
Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya
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CXCR4-using HIV type 1 variants are more commonly found in peripheral blood mononuclear cell DNA than in plasma RNA
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Prevalence and epidemiology of HIV type 1 drug resistance among newly diagnosed therapy-naive patients in Belgium from 2003 to 2006
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- Journal Article
- A1
- open access
Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: Analysis of the HIV-2 Belgium and Luxembourg database
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- Journal Article
- A1
- open access
Maraviroc: integration of a new antiretroviral drug class into clinical practice
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Impact of Delta 32-CCR5 heterozygosity on HIV-1 genetic evolution and variability - A study of 4 individuals infected with closely related HIV-1 strains
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Detection of drug resistance mutations as a predictor of subsequent virological failure in patients with HIV-1 viral rebounds of less than 1,000 RNA copies/ml
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Feasibility of detecting human immunodeficiency virus type 1 drug resistance in DNA extracted from whole blood or dried blood spots
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Evaluation of two commercially available alternatives for HIV-1 viral load testing in resource-limited settings
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A sensitive in-house RT-PCR genotyping system for combined detection of plasma HIV-1 and assessment of drug resistance
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Mortality among HIV-1-infected women according to children's feeding modality - An individual patient data meta-analysis
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The latent HIV-1 reservoir in patients undergoing HAART: an archive of pre-HAART drug resistance
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The AIDS epidemic: the spread of a deadly disease in the biotech era
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Low efficacy of nevirapine (HIVNET012) in preventing perinatal HIVA transmission in a real-life situation
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Drug-resistant variants that evolve during nonsuppressive therapy persist in HIV-1-infected peripheral blood mononuclear cells after long-term highly active antiretroviral therapy
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Placental malaria and perinatal transmission of human immunodeficiency virus type 1
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Diversity of the human immunodeficiency virus type 1 (HIV-1) env sequence after vertical transmission in mother-child pairs infected with HIV-1 subtype A
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Placental inflammation and perinatal transmission of HIV-1
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Prevalence of genotypic resistance among antiretroviral drug-naive HTV-1-infected patients in Belgium
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Vaginal lavage with chlorhexidine during labour to reduce mother-to-child HIV transmission: clinical trial in Mombasa, Kenya.
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Correlation between maternal and infant HIV infection and low birth weight: a study in Mombasa, Kenya
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Baseline HIV type 1 genotypic resistance to a newly added nucleoside analog is predictive of virologic failure of the new therapy.
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Blinded, multicenter quality control study for the quantification of human immunodeficiency virus type 1 RNA in plasma by the Belgian AIDS reference laboratories.
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Exposure to HIV-1 during delivery and mother-to-child transmission.
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Interruption of reverse transcriptase inhibitors or a switch from reverse transcriptase to protease inhibitors resulted in a fast reappearance of virus strains with a reverse transcriptase inhibitor-sensitive genotype.
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Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells
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Prevention of congenital toxoplasmosis in Szeged, Hungary.
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Line probe assay for rapid detection of drug-selected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene.
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Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
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Isolation of HIV-1 RNA from plasma: Evaluation of eight different extraction methods.
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Mogelijkheden en obstakels voor toepassing van DNA en RNA amplificatie en hybridisatietechnieken in de diagnostiek van infecties.