prof. dr. Lothar Steidler
No current affiliation with UGent
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Paracellular entry of interleukin-10 producing Lactococcus lactis in inflamed intestinal mucosa in mice
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Intracellular accumulation of trehalose protects Lactococcus lactis from freeze-drying damage and bile toxicity and increases gastric acid resistance
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Therapeutic drug delivery by genetically modified Lactococcus lactis
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Altered gut transcriptome in spondyloarthropathy
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Genetically modified Lactococcus lactis: novel tools for drug delivery
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Clinical potential of Lactococcus lactis mediated delivery of human Interleukin-10 and Trefoil Factors
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A phase I trial with Transgenic bacteria expressing interleukin-10 in Crohn's disease
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- Journal Article
- A1
- open access
CARD15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn's disease
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Development of an enteric-coated formulation containing freeze-dried, viable recombinant Lactococcus lactis for the ileal mucosal delivery of human interleukin-10
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Evaluation of extrusion/spheronisation, layering and compaction for the preparation of an oral, multi-particulate formulation of viable, hIL-10 producing Lactococcus lactis