prof. dr. Xavier Saelens

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STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne J. F. Kaptein, Rong Li, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Carolien De Keyzer, Lindsey Bervoets, Sapna Sharma, et al.

(2020) NATURE COMMUNICATIONS. 11(1).

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Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice

Lien Van Hoecke (UGent) , Stephanie Riederer, Xavier Saelens (UGent) , Gerd Sutter and Juan Jose Rojas

(2020) ONCOIMMUNOLOGY. 9(1).

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The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines Is determined by the route of administration

Lien Van Hoecke (UGent) , Kenny Roose (UGent) , Marlies Ballegeer (UGent) , Zifu Zhong (UGent) , Niek Sanders (UGent) , Stefaan De Koker (UGent) , Xavier Saelens (UGent) and Sandra Van Lint (UGent)

(2020) MOLECULAR THERAPY-NUCLEIC ACIDS. 22. p.373-381

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Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation

Laurens Raes, Stephan Stremersch (UGent) , Juan Fraire (UGent) , Toon Brans (UGent) , Glenn Goetgeluk (UGent) , Stijn De Munter (UGent) , Lien Van Hoecke (UGent) , Rein Verbeke (UGent) , Jelter Van Hoeck, Ranhua Xiong (UGent) , et al.

(2020) NANO-MICRO LETTERS. 12(1).

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Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant

Bram Van Den Eeckhout (UGent) , Lien Van Hoecke (UGent) , Elianne Burg (UGent) , Sandra Van Lint (UGent) , Frank Peelman (UGent) , Niko Kley, Gilles Uzé, Xavier Saelens (UGent) , Jan Tavernier (UGent) and Sarah Gerlo (UGent)

(2020) NPJ VACCINES. 5(1).

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Selected IL-1 activity on CD8+ T cells allows for safe enhancement of cellular immune responses

Bram Van Den Eeckhout (UGent) , Lien Van Hoecke (UGent) , Elianne Burg (UGent) , Sandra Van Lint (UGent) , Frank Peelman (UGent) , Niko Kley, Gilles Uzé, Xavier Saelens (UGent) , Jan Tavernier (UGent) and Sarah Gerlo (UGent)

(2020) T Cell Memory, Abstracts.

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mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice

Lien Van Hoecke (UGent) , Rein Verbeke (UGent) , Dorien De Vlieger, Heleen Dewitte (UGent) , Kenny Roose (UGent) , Sharon Van Nevel (UGent) , Olga Krysko (UGent) , Claus Bachert (UGent) , Bert Schepens (UGent) , Ine Lentacker (UGent) , et al.

(2020) MOLECULAR THERAPY-NUCLEIC ACIDS. 20. p.777-787

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Reverse engineering synthetic antiviral amyloids

Emiel Michiels, Kenny Roose (UGent) , Rodrigo Gallardo, Ladan Khodaparast, Laleh Khodaparast, Rob van der Kant, Maxime Siemons, Bert Houben, Meine Ramakers, Hannah Wilkinson, et al.

(2020) NATURE COMMUNICATIONS. 11(1).

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Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies

Daniel Wrapp, Dorien De Vlieger, Kizzmekia S. Corbett, Gretel M. Torres, Nianshuang Wang, Wander Van Breedam (UGent) , Kenny Roose (UGent) , Loes van Schie (UGent) , Markus Hoffmann, Stefan Poehlmann, et al.

(2020) CELL. 181(5). p.1004-1015

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Miscellaneous

Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies (vol 181, pg 1004, 2020)

Daniel Wrapp, Dorien De Vlieger, Kizzmekia S. Corbett, Gretel M. Torres, Nianshuang Wang, Wander Van Breedam (UGent) , Kenny Roose (UGent) , Loes van Schie (UGent) , Markus Hoffmann, Stefan Pohlmann, et al.

(2020) CELL. 181(6). p.1436-1441

Academic Bibliography

prof. dr. Xavier Saelens

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice

The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines Is determined by the route of administration

Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation

Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant

Selected IL-1 activity on CD8+ T cells allows for safe enhancement of cellular immune responses

mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice

Reverse engineering synthetic antiviral amyloids

Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies

Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies (vol 181, pg 1004, 2020)

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