ereprof. dr. Georges Leclercq

Journal Article
A1
open access

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

Lore Billiet (UGent) , Laurenz De Cock (UGent) , Guillem Sanchez Sanchez, Rupert Mayer (UGent) , Glenn Goetgeluk (UGent) , Stijn De Munter (UGent) , Melissa Pille (UGent) , Joline Ingels (UGent) , Hanne Jansen (UGent) , Karin Weening (UGent) , et al.

(2023) JOURNAL OF EXPERIMENTAL MEDICINE. 220(6).

Add to list

Journal Article
A1
open access

IRF2 is required for development and functional maturation of human NK cells

Eva Persyn (UGent) , Sigrid Wahlen (UGent) , Laura Kiekens (UGent) , Wouter Van Loocke (UGent) , Hannah Siwe (UGent) , Els Van Ammel (UGent) , Zenzi De Vos (UGent) , Filip Van Nieuwerburgh (UGent) , Patrick Matthys, Tom Taghon (UGent) , et al.

(2022) FRONTIERS IN IMMUNOLOGY. 13.

Add to list

Journal Article
A1
open access

Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development

Juliette Roels (UGent) , Jolien Van Hulle (UGent) , Marieke Lavaert, Anna Kuchmiy (UGent) , Steven Strubbe (UGent) , Tom Putteman (UGent) , Bart Vandekerckhove (UGent) , Georges Leclercq (UGent) , Filip Van Nieuwerburgh (UGent) , Lena Böhme (UGent) , et al.

(2022) FRONTIERS IN IMMUNOLOGY. 13.

Add to list

Journal Article
A1
open access

T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells

Laura Kiekens (UGent) , Sigrid Wahlen (UGent) , Eva Persyn (UGent) , Zenzi De Vos (UGent) , Tom Taghon (UGent) , Bart Vandekerckhove (UGent) and Georges Leclercq (UGent)

(2022) FRONTIERS IN IMMUNOLOGY. 13.

Add to list

Journal Article
A1
open access

Severe COVID-19 patients display hyper-activated NK cells and NK cell-platelet aggregates

Bert Malengier-Devlies, Jessica Filtjens (UGent) , Kourosh Ahmadzadeh, Bram Boeckx, Jessica Vandenhaute, Amber De Visscher, Eline Bernaerts, Tania Mitera, Cato Jacobs, Lore Vanderbeke, et al.

(2022) FRONTIERS IN IMMUNOLOGY. 13.

Add to list

Journal Article
A1
open access

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

Sigrid Wahlen (UGent) , Filip Matthijssens (UGent) , Wouter Van Loocke (UGent) , Sylvie Taveirne (UGent) , Laura Kiekens (UGent) , Eva Persyn (UGent) , Els Van Ammel (UGent) , Zenzi De Vos (UGent) , Stijn De Munter (UGent) , Patrick Matthys, et al.

(2022) ELIFE. 11.

Add to list

Journal Article
A1
open access

TXNIP promotes human NK cell development but is dispensable for NK cell functionality

Eva Persyn (UGent) , Sigrid Wahlen (UGent) , Laura Kiekens (UGent) , Sylvie Taveirne (UGent) , Wouter Van Loocke (UGent) , Els Van Ammel (UGent) , Filip Van Nieuwerburgh (UGent) , Tom Taghon (UGent) , Bart Vandekerckhove (UGent) , Pieter Van Vlierberghe (UGent) , et al.

(2022) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 23(19).

Add to list

Journal Article
A1
open access

Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials

Joline Ingels (UGent) , Laurenz De Cock (UGent) , Rupert Mayer (UGent) , Pam Devreker (UGent) , Karin Weening (UGent) , Kelly Heyns (UGent) , Nele Lootens (UGent) , Saskia De Smet (UGent) , Marieke Brusseel (UGent) , Stijn De Munter (UGent) , et al.

(2022) CYTOTHERAPY. 24(2). p.213-222

Add to list

Journal Article
A1
open access

In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality

Sarah Bonte (UGent) , Stijn De Munter (UGent) , Lore Billiet (UGent) , Glenn Goetgeluk (UGent) , Joline Ingels (UGent) , Hanne Jansen (UGent) , Melissa Pille (UGent) , Laurenz De Cock (UGent) , Karin Weening (UGent) , Tom Taghon (UGent) , et al.

(2021) ONCOIMMUNOLOGY. 10(1).

Add to list

Journal Article
A1
open access

T-BET and EOMES accelerate and enhance functional differentiation of human natural killer cells

Laura Kiekens (UGent) , Wouter Van Loocke (UGent) , Sylvie Taveirne (UGent) , Sigrid Wahlen (UGent) , Eva Persyn (UGent) , Els Van Ammel (UGent) , Zenzi De Vos (UGent) , Patrick Matthys, Filip Van Nieuwerburgh (UGent) , Tom Taghon (UGent) , et al.

(2021) FRONTIERS IN IMMUNOLOGY. 12.

Academic Bibliography

ereprof. dr. Georges Leclercq

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

IRF2 is required for development and functional maturation of human NK cells

Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development

T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells

Severe COVID-19 patients display hyper-activated NK cells and NK cell-platelet aggregates

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

TXNIP promotes human NK cell development but is dispensable for NK cell functionality

Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials

In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality

T-BET and EOMES accelerate and enhance functional differentiation of human natural killer cells

Contents

Support

Contact