ereprof. dr. Georges Leclercq

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Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline Ingels (UGent) , Laurenz De Cock (UGent) , Dieter Stevens (UGent) , Rupert Mayer (UGent) , Fabien Henri Thery (UGent) , Guillem Sanchez Sanchez, David Vermijlen, Karin Weening (UGent) , Saskia De Smet (UGent) , Nele Lootens (UGent) , et al.

(2024) CELL REPORTS MEDICINE. 5(5).

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Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen-induced exhaustion

Stijn De Munter (UGent) , Juliane L. Buhl, Laurenz De Cock (UGent) , Alexander Van Parys (UGent) , Willem Daneels (UGent) , Eva Pascal (UGent) , Lucas Deseins (UGent) , Joline Ingels (UGent) , Glenn Goetgeluk (UGent) , Hanne Jansen, et al.

(2024) CANCER IMMUNOLOGY RESEARCH. 12(9). p.1236-1251

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TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice

Mario Ruiz Pérez (UGent) , Christian Maueröder (UGent) , Wolf Steels (UGent) , Bruno Verstraeten (UGent) , Sahine Lameire (UGent) , Wei Xie (UGent) , Laura Wyckaert (UGent) , Jelle Huysentruyt, Tatyana Divert (UGent) , Ria Roelandt (UGent) , et al.

(2024) CELLULAR & MOLECULAR IMMUNOLOGY. 21. p.807-825

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Type 1 immunity enables neonatal thymic ILC1 production

Peter Tougaard (UGent) , Mario Ruiz Pérez (UGent) , Wolf Steels (UGent) , Jelle Huysentruyt, Bruno Verstraeten (UGent) , Jessica Vetters (UGent) , Tatyana Divert (UGent) , Amanda Gonçalves (UGent) , Ria Roelandt (UGent) , Nozomi Takahashi (UGent) , et al.

(2024) SCIENCE ADVANCES. 10(3).

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Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF

Kai Ling Liang (UGent) , Juliette Roels (UGent) , Marieke Lavaert, Tom Putteman (UGent) , Lena Boehme (UGent) , Laurentijn Tilleman (UGent) , Imke Velghe (UGent) , Valentina Pegoretti, Inge Van de Walle (UGent) , Stephanie Sontag, et al.

(2023) NATURE IMMUNOLOGY. 24(3). p.474-486

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The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation

Melissa Pille (UGent) , John Avila, Guillem Sanchez Sanchez, Glenn Goetgeluk (UGent) , Stijn De Munter (UGent) , Hanne Jansen, Lore Billiet (UGent) , Karin Weening (UGent) , Haipeng Xue, Sarah Bonte (UGent) , et al.

(2023) FRONTIERS IN IMMUNOLOGY. 14.

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Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

Lore Billiet (UGent) , Laurenz De Cock (UGent) , Guillem Sanchez Sanchez, Rupert Mayer (UGent) , Glenn Goetgeluk (UGent) , Stijn De Munter (UGent) , Melissa Pille (UGent) , Joline Ingels (UGent) , Hanne Jansen, Karin Weening (UGent) , et al.

(2023) JOURNAL OF EXPERIMENTAL MEDICINE. 220(6).

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IRF2 is required for development and functional maturation of human NK cells

Eva Persyn, Sigrid Wahlen, Laura Kiekens, Wouter Van Loocke (UGent) , Hannah Siwe (UGent) , Els Van Ammel (UGent) , Zenzi De Vos (UGent) , Filip Van Nieuwerburgh (UGent) , Patrick Matthys, Tom Taghon (UGent) , et al.

(2022) FRONTIERS IN IMMUNOLOGY. 13.

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Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development

Juliette Roels (UGent) , Jolien Van Hulle (UGent) , Marieke Lavaert, Anna Kuchmiy (UGent) , Steven Strubbe, Tom Putteman (UGent) , Bart Vandekerckhove (UGent) , Georges Leclercq (UGent) , Filip Van Nieuwerburgh (UGent) , Lena Boehme (UGent) , et al.

(2022) FRONTIERS IN IMMUNOLOGY. 13.

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T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells

Laura Kiekens, Sigrid Wahlen, Eva Persyn, Zenzi De Vos (UGent) , Tom Taghon (UGent) , Bart Vandekerckhove (UGent) and Georges Leclercq (UGent)

(2022) FRONTIERS IN IMMUNOLOGY. 13.

Academic Bibliography

ereprof. dr. Georges Leclercq

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen-induced exhaustion

TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice

Type 1 immunity enables neonatal thymic ILC1 production

Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF

The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

IRF2 is required for development and functional maturation of human NK cells

Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development

T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells

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