Magda De Smedt

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GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

Inge Van de Walle (UGent) , Anne-Catherine Dolens, Kaat Durinck (UGent) , Katrien De Mulder (UGent) , Wouter Van Loocke (UGent) , Sagar Damle, Els Waegemans (UGent) , Jelle De Medts (UGent) , Imke Velghe (UGent) , Magda De Smedt (UGent) , et al.

(2016) NATURE COMMUNICATIONS. 7.

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Notch3 activation is sufficient but not required for inducing human T-lineage specification

Els Waegemans (UGent) , Inge Van de Walle (UGent) , Jelle De Medts (UGent) , Magda De Smedt (UGent) , Tessa Kerre (UGent) , Bart Vandekerckhove (UGent) , Georges Leclercq (UGent) , Tao Wang, Jean Plum (UGent) and Tom Taghon (UGent)

(2014) JOURNAL OF IMMUNOLOGY. 193(12). p.5997-6004

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Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength

Inge Van de Walle (UGent) , Els Waegemans (UGent) , Jelle De Medts (UGent) , Greet De Smet (UGent) , Magda De Smedt (UGent) , SYLVIA SNAUWAERT (UGent) , Bart Vandekerckhove (UGent) , Tessa Kerre (UGent) , Georges Leclercq (UGent) , Jean Plum (UGent) , et al.

(2013) JOURNAL OF EXPERIMENTAL MEDICINE. 210(4). p.683-697

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Notch ligands control the human alpha beta/gamma delta lineage choice through receptor-specific induction of differential Notch signal strength

Tom Taghon (UGent) , Inge Van de Walle (UGent) , Els Waegemans (UGent) , Jelle De Medts (UGent) , Greet De Smet (UGent) , Magda De Smedt (UGent) , Bart Vandekerckhove (UGent) , Tessa Kerre (UGent) , Georges Leclercq (UGent) , Tao Wang, et al.

(2012) JOURNAL OF IMMUNOLOGY. 188.

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CD27-deficient mice show normal NK-cell differentiation but impaired function upon stimulation

Veerle De Colvenaer (UGent) , Sylvie Taveirne (UGent) , Maarten Delforche (UGent) , Magda De Smedt (UGent) , Bart Vandekerckhove (UGent) , Tom Taghon (UGent) , Louis Boon, Jean Plum (UGent) and Georges Leclercq (UGent)

(2011) IMMUNOLOGY AND CELL BIOLOGY. 89(7). p.803-811

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Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

Inge Van de Walle (UGent) , Greet De Smet (UGent) , Martina Gärtner, Magda De Smedt (UGent) , Els Waegemans (UGent) , Bart Vandekerckhove (UGent) , Georges Leclercq (UGent) , Jean Plum (UGent) , Jon C Aster, Irwin D Bernstein, et al.

(2011) BLOOD. 117(17). p.4449-4459

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T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38-/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells

Magda De Smedt (UGent) , Georges Leclercq (UGent) , Bart Vandekerckhove (UGent) , Tessa Kerre (UGent) , Tom Taghon (UGent) and Jean Plum (UGent)

(2011) HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. 96(5). p.646-654

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Continuous CD27 triggering in vivo strongly reduces NK cell numbers

Veerle De Colvenaer (UGent) , Sylvie Taveirne (UGent) , Jörg Hamann, Alex M de Bruin, Magda De Smedt (UGent) , Tom Taghon (UGent) , Bart Vandekerckhove (UGent) , Jean Plum (UGent) , René van Lier and Georges Leclercq (UGent)

(2010) EUROPEAN JOURNAL OF IMMUNOLOGY. 40(4). p.1107-1117

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Functionally mature CD4 and CD8 TCRαβ cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells

Stefanie Van Coppernolle (UGent) , Greet Verstichel (UGent) , Frank Timmermans (UGent) , Imke Velghe (UGent) , David Vermijlen, Magda De Smedt (UGent) , Georges Leclercq (UGent) , Jean Plum (UGent) , Tom Taghon (UGent) , Bart Vandekerckhove (UGent) , et al.

(2009) JOURNAL OF IMMUNOLOGY. 183(8). p.4859-4870

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Generation of T cells from human embryonic stem cell-derived hematopoietic zones

Frank Timmermans (UGent) , Imke Velghe (UGent) , Lieve Vanwalleghem, Magda De Smedt (UGent) , Stefanie Van Coppernolle (UGent) , Tom Taghon (UGent) , Harry Moore, Georges Leclercq (UGent) , Anton Langerak, Tessa Kerre (UGent) , et al.

(2009) JOURNAL OF IMMUNOLOGY. 182(11). p.6879-6888

Academic Bibliography

Magda De Smedt

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

Notch3 activation is sufficient but not required for inducing human T-lineage specification

Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength

Notch ligands control the human alpha beta/gamma delta lineage choice through receptor-specific induction of differential Notch signal strength

CD27-deficient mice show normal NK-cell differentiation but impaired function upon stimulation

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38-/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells

Continuous CD27 triggering in vivo strongly reduces NK cell numbers

Functionally mature CD4 and CD8 TCRαβ cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells

Generation of T cells from human embryonic stem cell-derived hematopoietic zones

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