dr. Eva Blondeel

PhD Thesis

Spheroid-based tools as stepping stones towards rigorous and mechanistically insightful research.

Eva Blondeel (UGent)

(2025)

Miscellaneous

Sequential orthogonal assays for longitudinal and endpoint characterization of three-dimensional spheroids (Apr, 10.1038/s41596-025-01150-y, 2025)

Eva Blondeel (UGent) , Sam Ernst (UGent) , Felix De Vuyst (UGent) , Ákos Diósdi, Cláudio Pinheiro (UGent) , Diogo Miguel Monteiro Estêvão (UGent) , Pekka Rappu, Robin Boiy (UGent) , Sandor Dedeyne (UGent) , Ligia Craciun, et al.

(2025) NATURE PROTOCOLS.

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Sequential orthogonal assays for longitudinal and endpoint characterization of three-dimensional spheroids

Eva Blondeel (UGent) , Sam Ernst (UGent) , Felix De Vuyst (UGent) , Ákos Diósdi, Cláudio Pinheiro (UGent) , Diogo Estêvão, Pekka Rappu, Robin Boiy (UGent) , Sandor Dedeyne (UGent) , Ligia Craciun, et al.

(2025) NATURE PROTOCOLS. 20(10). p.2899-2941

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The Spheroid Light Microscopy Image Atlas for morphometrical analysis of three-dimensional cell cultures

Eva Blondeel (UGent) , Arne Peirsman, Stephanie Vermeulen (UGent) , Filippo Piccinini, Felix De Vuyst (UGent) , Diogo Miguel Monteiro Estêvão (UGent) , Sayida Al-Jamei, Martina Bedeschi, Gastone Castellani, Tânia Cruz, et al.

(2025) SCIENTIFIC DATA. 12(1).

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Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties

Stephanie Vermeulen (UGent) , Sam Ernst (UGent) , Eva Blondeel (UGent) , Zihan Xia (UGent) , Pekka Rappu, Jyrki Heino, Sandor Dedeyne (UGent) , Hannelore Denys (UGent) , Gwen Sys (UGent) , Stefanie Gijsels (UGent) , et al.

(2024) SCIENTIFIC REPORTS. 14(1).

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Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer

Cristina Muntean, Eva Blondeel (UGent) , Laure Harinck (UGent) , Kunal Pednekar, Jai Prakash, Olivier De Wever (UGent) , Jeanne Leblond Chain, Stefaan De Smedt (UGent) , Katrien Remaut (UGent) and Koen Raemdonck (UGent)

(2023) INTERNATIONAL JOURNAL OF PHARMACEUTICS. 644.

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A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment

Elly De Vlieghere (UGent) , Koen Van de Vijver (UGent) , Eva Blondeel (UGent) , Nathan Carpentier (UGent) , Rouba Ghobeira (UGent) , Jarne Pauwels (UGent) , Sebastian Riemann (UGent) , Manon Minsart (UGent) , Charlotte Fieuws, Johanna Mestach (UGent) , et al.

(2023) BIOMATERIALS RESEARCH. 27(1).

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Direct lysis of 3D cell cultures for RT-qPCR gene expression quantification

Fien Gysens, Lisa Ostyn (UGent) , Ellen Goeteyn, Eva Blondeel (UGent) , Justine Nuytens (UGent) , Olivier De Wever (UGent) , Eric de Bony de Lavergne (UGent) , Aurélie Crabbé (UGent) and Pieter Mestdagh (UGent)

(2023) SCIENTIFIC REPORTS. 13(1).

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Hybrid scaffolds as long-term in vitro co-culture model for targeted treatment of ovarian cancer

Elly De Vlieghere (UGent) , Eva Blondeel (UGent) , Nathan Carpentier (UGent) , Koen Van de Vijver (UGent) , Sandra Van Vlierberghe (UGent) and Olivier De Wever (UGent)

(2022) 32rd Annual Conference of the European Society for Biomaterials (ESB 2022), Abstracts.

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Preclinical platform for long-term evaluation of drug efficacy using three-dimensional tumor-stroma spheroids embedded in stiffness-tunable scaffolds

Elly De Vlieghere (UGent) , Eva Blondeel (UGent) , Nathan Carpentier (UGent) , Manon Minsart (UGent) , Koen Van de Vijver (UGent) , Sandra Van Vlierberghe (UGent) and Olivier De Wever (UGent)

(2022) Tissue Engineering, 9th Belgian symposium, Abstracts.

Academic Bibliography

dr. Eva Blondeel

Spheroid-based tools as stepping stones towards rigorous and mechanistically insightful research.

Sequential orthogonal assays for longitudinal and endpoint characterization of three-dimensional spheroids (Apr, 10.1038/s41596-025-01150-y, 2025)

Sequential orthogonal assays for longitudinal and endpoint characterization of three-dimensional spheroids

The Spheroid Light Microscopy Image Atlas for morphometrical analysis of three-dimensional cell cultures

Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties

Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment

Direct lysis of 3D cell cultures for RT-qPCR gene expression quantification

Hybrid scaffolds as long-term in vitro co-culture model for targeted treatment of ovarian cancer

Preclinical platform for long-term evaluation of drug efficacy using three-dimensional tumor-stroma spheroids embedded in stiffness-tunable scaffolds

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