Lien Verboom

Journal Article
A1
open access

Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion

Maria Giulia Doglio (UGent) , Lien Verboom (UGent) , Emily Ruilova Sosoranga, Ulrika Frising (UGent) , Tomoko Asaoka (UGent) , Yannick Gansemans (UGent) , Filip Van Nieuwerburgh (UGent) , Geert van Loo (UGent) and Andy Wullaert (UGent)

(2023) SCIENCE IMMUNOLOGY. 8(89).

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PhD Thesis

Unravelling the role of OTULIN in liver and intestinal pathology

Lien Verboom (UGent)

(2023)

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Journal Article
A1
open access

OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection

Lien Verboom (UGent) , Christopher Anderson (UGent) , Maude Jans (UGent) , Ioanna Petta (UGent) , Gillian Blancke (UGent) , Arne Martens (UGent) , Mozes Sze (UGent) , Tino Hochepied (UGent) , Kodi Ravichandran (UGent) , Lars Vereecke (UGent) , et al.

(2023) CELL DEATH & DISEASE. 14(8).

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Journal Article
A1
open access

OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity

Esther Hoste (UGent) , Kim Lecomte (UGent) , Karl Annusver, Niels Vandamme (UGent) , Jana Roels (UGent) , Sophia Maschalidi (UGent) , Lien Verboom (UGent) , Hanna-Kaisa Vikkula (UGent) , Mozes Sze (UGent) , Lisette Van Hove, et al.

(2021) NATURE COMMUNICATIONS. 12(1).

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OTULIN in NF-κB signaling, cell death, and disease

Lien Verboom (UGent) , Esther Hoste (UGent) and Geert van Loo (UGent)

(2021) TRENDS IN IMMUNOLOGY. 42(7). p.590-603

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Journal Article
A1
open access

OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis

Lien Verboom (UGent) , Arne Martens (UGent) , Dario Priem (UGent) , Esther Hoste (UGent) , Mozes Sze (UGent) , Hanna-Kaisa Vikkula (UGent) , Lisette Van Hove, Sofie Voet, Jana Roels (UGent) , Jonathan Maelfait (UGent) , et al.

(2020) CELL REPORTS. 30(7). p.2237-2247

Academic Bibliography

Lien Verboom

Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion

Unravelling the role of OTULIN in liver and intestinal pathology

OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection

OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity

OTULIN in NF-κB signaling, cell death, and disease

OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis

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