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- Journal Article
- A1
- open access
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
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- Journal Article
- A1
- open access
Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells
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Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ
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- Journal Article
- A1
- open access
Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs : involvement of MAPK and NF-κB pathways
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- Journal Article
- A1
- open access
How the venom from the ectoparasitoid wasp Nasonia vitripennis exhibits anti-inflammatory properties on mammalian cell lines
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- Journal Article
- A1
- open access
Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state
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- Journal Article
- A1
- open access
Pharmacological levels of withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells
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Cancer chemoprevention by dietary polyphenols
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The serotonin 5-HT₇ receptors: two decades of research
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The role of serine- and metalloproteases in Nasonia vitripennis venom in cell death related processes towards a Spodoptera frugiperda Sf21 cell line
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- Conference Paper
- C3
- open access
Flavanols: what do we know about their mechanisms of action?
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Flavanols modulate the transcription of genes involved in cardiovascular pathology with heterogenic changes of their DNA methylation state: FLAVIOLA associated
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Molecular insight in the multifunctional activities of Withaferin A
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- Book Chapter
- open access
Phytochemicals and cancer chemoprevention: epigenetic friends or foe?
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ABINs inhibit EGF receptor-mediated NF-kappa B activation and growth of EGF receptor-overexpressing tumour cells
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T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappa B inhibitor A20
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Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappa B activation
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Hepatic tumor necrosis factor signaling and nuclear factor-kappa B: Effects on liver homeostasis and beyond
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LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappa B activation
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Abin2
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Abin1
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Ubiquitin: tool and target for intracellular NF-κB inhibitors
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Mechanisms of crosstalk between TNF-induced NF-kappa B and JNK activation in hepatocytes
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A novel link between Lck, Bak expression and chemosensitivity
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TNF alpha- and IKK beta-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKK gamma and NF-kappa B activation
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Adenoviral gene transfer of ABIN-1 protects mice from TNF/galactosamine-induced acute liver failure and lethality
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Adenoviral gene transfer of the NF-kappa B inhibitory protein ABIN-1 decreases allergic airway inflammation in a murine asthma model
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A20 inhibits NF-κB activation by dual ubiquitin-editing functions
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The yeast three-hybrid system as a tool to study caspases
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Yeast two-hybrid screening for proteins interacting with the anti-apoptotic protein A20
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NF-κB activation by tumor necrosis factor and interleukin-1
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Nuclear factor-kappa B plays a central role in tumour necrosis factor-mediated liver disease
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Structure-function analysis of the A20-binding inhibitor of NF-kappa B activation, ABIN-1
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A novel type of deubiquitinating enzyme*
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Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas
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Crosstalk between NF-êB-activating and apoptosis-inducing proteins of the TNF-receptor complex
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Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2.
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Functional redundancy of the zinc fingers of A20 for inhibition of NF-kappa B activation and protein-protein interactions.
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Isolation and characterization of two novel A20-like proteins.
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A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis.
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Identificatie en karakterisering van cellulaire inhibitoren van NF-kB-afhankelijke genexpressie
(1999) -
The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases.
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The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappa B activation at the level of TRAF6.
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Inhibition of Tumor Necrosis Factor-induced necrotic cell death by the zinc finger protein A20.
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- Journal Article
- A1
- open access
The zinc finger protein A20 inhibits TNF-induced NF-kappa B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappa B-inhibiting protein ABIN.
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Tumour necrosis factor: intracellular mechanism of action
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A20 inhibits NF-kappa B activation independently of binding to 14-3-3 proteins.
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A20, an inhibitor of cell death, self-associates by its zinc finger domain.
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TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.
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ENHANCEMENT OF TUMOR-NECROSIS-FACTOR CYTOTOXICITY BY LITHIUM-CHLORIDE IS ASSOCIATED WITH INCREASED INOSITOL PHOSPHATE ACCUMULATION.