Jeroen Spanoghe

Conference Paper
C3
open access

Towards therapeutic innovation in temporal lobe epilepsy : spatially selective and closed-loop adenosinergic modulation of dentate gyrus excitability through photopharmacology

Marijke Vergaelen (UGent) , Kristl Vonck (UGent) , Jeroen Spanoghe (UGent) , Jeroen Missinne (UGent) , Simona Manzella, Serge Van Calenbergh (UGent) , Paul Boon (UGent) and Robrecht Raedt (UGent)

(2026) FENS forum 2026, Book of Abstracts.

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Conference Paper
C3
open access

Towards therapeutic innovation in temporal lobe epilepsy : spatially selective and closed-loop adenosinergic modulation of dentate gyrus excitability through photopharmacology

Marijke Vergaelen (UGent) , Kristl Vonck (UGent) , Jeroen Spanoghe (UGent) , Jeroen Missinne (UGent) , Simona Manzella, Serge Van Calenbergh (UGent) , Paul Boon (UGent) and Robrecht Raedt (UGent)

(2026) 5th International Symposium on Photopharmacology, Book of Abstracts.

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Journal Article
A1
open access

Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist

Erine Craey, Marijke Vergaelen (UGent) , Serge Van Calenbergh (UGent) , Jeroen Spanoghe (UGent) , Evelien Carrette (UGent) , Kristl Vonck (UGent) , Paul Boon (UGent) , Wytse Wadman (UGent) and Robrecht Raedt (UGent)

(2026) BRITISH JOURNAL OF PHARMACOLOGY. 183(10). p.2578-2591

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Conference Paper
C3
open access

Towards therapeutic innovation in temporal lobe epilepsy : spatially selective and closed-loop adenosinergic modulation of dentate gyrus excitability through photopharmacology

Marijke Vergaelen (UGent) , Kristl Vonck (UGent) , Jeroen Spanoghe (UGent) , Jeroen Missinne (UGent) , Simona Manzella, Serge Van Calenbergh (UGent) , Paul Boon (UGent) and Robrecht Raedt (UGent)

(2025) American Epilepsy Society Annual Meeting 2025, Book of Abstracts.

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Conference Paper
C3
open access

Towards therapeutic innovation in temporal lobe epilepsy : focal adenosinergic modulation of hippocampal excitability

Marijke Vergaelen (UGent) , Kristl Vonck (UGent) , Jeroen Spanoghe (UGent) , Jeroen Missinne (UGent) , Simona Manzella, Serge Van Calenbergh (UGent) , Paul Boon (UGent) and Robrecht Raedt (UGent)

(2025) EPILEPSIA. In Epilepsia 66(Supplement 4). p.S130-S131

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PhD Thesis

Photopharmacological adenosine A1 receptor modulation for the suppression of epileptic seizures : a proof of concept

Jeroen Spanoghe (UGent)

(2025)

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Journal Article
A1
open access

Photopharmacological activation of adenosine A1 receptor signaling suppresses seizures in a mouse model for temporal lobe epilepsy

Jeroen Spanoghe (UGent) , Evelien Wynendaele (UGent) , Marijke Vergaelen (UGent) , Maren De Colvenaer (UGent) , Tina Mariman, Kristl Vonck (UGent) , Evelien Carrette (UGent) , Wytse Wadman (UGent) , Erine Craey, Lars Emil Larsen (UGent) , et al.

(2025) JOURNAL OF CONTROLLED RELEASE. 381.

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Conference Paper
C1
open access

Embedded system for responsive optogenetic control of spontaneous seizures in a preclinical temporal lobe epilepsy model

Sofie Lasure (UGent) , Lien De Schaepmeester (UGent) , Sielke Caestecker (UGent) , Jeroen Spanoghe (UGent) , Marijke Vergaelen (UGent) , Rik Verplancke (UGent) , Johannes Vierock, Robrecht Raedt (UGent) and Pieter Bauwens (UGent)

(2025) Proceedings of the 18th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1. p.88-99

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Journal Article
A2
open access

Effects of intracerebroventricular administration of dimethyl sulfoxide on hippocampal electrophysiology in mice

Jeroen Spanoghe (UGent) , Arne Van Acker, Evelien Carrette (UGent) , Kristl Vonck (UGent) , Paul Boon (UGent) and Robrecht Raedt (UGent)

(2025) IBRO NEUROSCIENCE REPORTS. 18. p.378-383

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Conference Paper
C3
open access

Towards therapeutic innovation in temporal lobe epilepsy : focal adenosinergic modulation of hippocampal excitability

Marijke Vergaelen (UGent) , Jeroen Spanoghe (UGent) , Jeroen Missinne (UGent) , Serge Van Calenbergh (UGent) , Kristl Vonck (UGent) , Paul Boon (UGent) and Robrecht Raedt (UGent)

(2024) EUROPEAN JOURNAL OF NEUROLOGY. In European Journal of Neurology 31(Supplement 1). p.296-297

Academic Bibliography

Jeroen Spanoghe

Towards therapeutic innovation in temporal lobe epilepsy : spatially selective and closed-loop adenosinergic modulation of dentate gyrus excitability through photopharmacology

Towards therapeutic innovation in temporal lobe epilepsy : spatially selective and closed-loop adenosinergic modulation of dentate gyrus excitability through photopharmacology

Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist

Towards therapeutic innovation in temporal lobe epilepsy : spatially selective and closed-loop adenosinergic modulation of dentate gyrus excitability through photopharmacology

Towards therapeutic innovation in temporal lobe epilepsy : focal adenosinergic modulation of hippocampal excitability

Photopharmacological adenosine A1 receptor modulation for the suppression of epileptic seizures : a proof of concept

Photopharmacological activation of adenosine A1 receptor signaling suppresses seizures in a mouse model for temporal lobe epilepsy

Embedded system for responsive optogenetic control of spontaneous seizures in a preclinical temporal lobe epilepsy model

Effects of intracerebroventricular administration of dimethyl sulfoxide on hippocampal electrophysiology in mice

Towards therapeutic innovation in temporal lobe epilepsy : focal adenosinergic modulation of hippocampal excitability

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