Academic Bibliography

Search 200 years of publications by Ghent University researchers.

Heleen Lauwers

Faculty of Pharmaceutical Sciences > Department of Pharmaceutics

ORCID iD: 0000-0001-8972-5275

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Combinatorial synthesis and evaluation of trialkyl galloyl amidoamine ionizable lipids for mRNA formulation

Bianka Golba, Irene De Franceschi (UGent) , Zifu Zhong (UGent) , Martijn Schuijs (UGent) , Claudia Mariela Brenis Gómez (UGent) , Heleen Lauwers (UGent) , Benoit Louage (UGent) , Iasona Sheshi (UGent) , Nezha Badi (UGent) , Bruno De Geest (UGent) , et al.

(2025) JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 147(30). p.26934-26943
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Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

Yong Chen (UGent) , Emily De Lombaerde, Aimee-Rose Bugler-Lamb (UGent) , Zifu Zhong (UGent) , Martijn Schuijs (UGent) , Claudia Mariela Brenis Gómez (UGent) , Jamie De Baere (UGent) , Mark Gontsarik (UGent) , Heleen Lauwers (UGent) , Kim Deswarte (UGent) , et al.

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 64(28).
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HER2 nanobody-poly(rhamnose) conjugates efficiently recruit anti-rhamnose antibodies from serum to the surface of HER2-expressing cells

Weiwei Mu (UGent) , Yong Chen (UGent) , Zifu Zhong (UGent) , Benoit Louage (UGent) , Heleen Lauwers (UGent) , Nick Devoogdt, Jurgen Haustraete (UGent) and Bruno De Geest (UGent)

(2024) CHEMISTRY OF MATERIALS. 36(20). p.10113-10124
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CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity

Tingting Ye, Zifu Zhong (UGent) , Federica Cappellesso, Kim Deswarte (UGent) , Yong Chen (UGent) , Heleen Lauwers (UGent) , Emily De Lombaerde, Mark Gontsarik (UGent) , Stefan Lienenklaus, Dorien Van Lysebetten, et al.

(2024) BIOMATERIALS. 311.
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Lysosomal trafficking and degradation of extracellular proteins via multivalent small molecule ligand display on dextran scaffolds

Benoit Louage (UGent) , Demi Defreyne (UGent) , Heleen Lauwers (UGent) , Jamie De Baere (UGent) , Annemiek Uvyn (UGent) , Haixia Peng, Yong Chen (UGent) and Bruno De Geest (UGent)

(2024) BIOMACROMOLECULES. 26(1). p.738-750
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Combinatorial screening of biscarbamate ionizable lipids identifies a low reactogenicity lipid for lipid nanoparticle mRNA delivery

Emily De Lombaerde, Yong Chen (UGent) , Tingting Ye, Julie Deckers (UGent) , Giulia Mencarelli, Kim Deswarte (UGent) , Heleen Lauwers (UGent) , Ruben De Coen (UGent) , Sabah Kasmi (UGent) , Sanne Bevers, et al.

(2024) ADVANCED FUNCTIONAL MATERIALS. 34(21). p.1-16
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Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue

Zifu Zhong (UGent) , Yong Chen (UGent) , Kim Deswarte (UGent) , Heleen Lauwers (UGent) , Emily De Lombaerde, Xiaole Cui (UGent) , Simon Van Herck (UGent) , Tingting Ye, Mark Gontsarik (UGent) , Stefan Lienenklaus, et al.

(2023) ADVANCED HEALTHCARE MATERIALS. 12(32).