dr. Tineke Vanderhaeghen

Journal Article
A1
open access

Comparative analysis of hepatic gene expression profiles in murine and porcine sepsis models

Fëllanza Halimi (UGent) , Tineke Vanderhaeghen (UGent) , Steven Timmermans (UGent) , Siska Croubels (UGent) , Claude Libert (UGent) and Jolien Vandewalle (UGent)

(2024) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 25(20).

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Journal Article
A1
open access

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

Céline Van Dender (UGent) , Steven Timmermans (UGent) , Ville Paakinaho, Tineke Vanderhaeghen (UGent) , Jolien Vandewalle (UGent) , Maarten Claes (UGent) , Bruno Garcia, Bart Roman (UGent) , Jan De Waele (UGent) , Siska Croubels (UGent) , et al.

(2024) EMBO MOLECULAR MEDICINE. 16(10). p.2485-2515

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Journal Article
A1
open access

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Charlotte Wallaeys (UGent) , Natalia Garcia Gonzalez (UGent) , Steven Timmermans (UGent) , Jolien Vandewalle (UGent) , Tineke Vanderhaeghen (UGent) , Somara De Beul (UGent) , Hester Dufoor (UGent) , Melanie Eggermont (UGent) , Elise Moens (UGent) , Victor Bosteels (UGent) , et al.

(2024) CELL HOST & MICROBE. 32(10). p.1725-1743

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Journal Article
A2
open access

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

Claudia Theys, Tineke Vanderhaeghen (UGent) , Evelien Van Dijck, Cedric Peleman, Anne Scheepers, Joe Ibrahim, Ligia Mateiu, Steven Timmermans (UGent) , Tom Vanden Berghe (UGent) , Sven M. Francque, et al.

(2024) FRONTIERS IN MOLECULAR MEDICINE. 3.

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Journal Article
A1
open access

Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression

Sofie Desmet, Jonathan Thommis (UGent) , Tineke Vanderhaeghen (UGent) , Edmee Vandenboorn, Dorien Clarisse (UGent) , Yunkun Li, Steven Timmermans (UGent) , Daria Fijalkowska (UGent) , Dariusz Ratman (UGent) , Evelien Van Hamme (UGent) , et al.

(2024) MOLECULAR METABOLISM. 84.

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Conference Paper
C3
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The pig as a translational animal to explore a new concept in the treatment of sepsis, today's largest unmet medical need

Fëllanza Halimi (UGent) , Charlotte Cuypers (UGent) , Bruna Alonso (UGent) , Eline Hermans (UGent) , Diethard Reckelbus (UGent) , Jolien Vandewalle (UGent) , Bruno Garcia, Antoine Herpain, Tineke Vanderhaeghen (UGent) , Céline Van Dender (UGent) , et al.

(2023) Research Day 2023, Abstracts.

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The pig as a translational animal model to explore a new concept in the treatment of sepsis, today's largest unmet medical need

Fëllanza Halimi (UGent) , Charlotte Cuypers (UGent) , Bruna Alonso (UGent) , Eline Hermans (UGent) , Diethard Reckelbus (UGent) , Jolien Vandewalle (UGent) , B. Garcia, A. Herpain, Tineke Vanderhaeghen (UGent) , Céline Van Dender (UGent) , et al.

(2023) JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS. 46(Supplement 1). p.33-34

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Journal Article
A1
open access

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Tineke Vanderhaeghen (UGent) , Steven Timmermans (UGent) , Melanie Eggermont (UGent) , Deepika Watts, Jolien Vandewalle (UGent) , Charlotte Wallaeys (UGent) , Louise Nuyttens (UGent) , Joyca De Temmerman, Tino Hochepied (UGent) , Sylviane Dewaele (UGent) , et al.

(2023) FRONTIERS IN IMMUNOLOGY. 14.

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Miscellaneous

Spns2/S1P : it takes two to tango with inflammation and metabolic rewiring during sepsis

Tineke Vanderhaeghen (UGent) , Jolien Vandewalle (UGent) and Claude Libert (UGent)

(2023) EMBO REPORTS. 24(8).

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Journal Article
A1
open access

Hepatic peroxisome proliferator-activated receptor alpha dysfunction in porcine septic shock

Jolien Vandewalle (UGent) , Bruno Garcia, Steven Timmermans (UGent) , Tineke Vanderhaeghen (UGent) , Lise Van Wyngene, Melanie Eggermont (UGent) , Hester Dufoor (UGent) , Céline Van Dender (UGent) , Fëllanza Halimi (UGent) , Siska Croubels (UGent) , et al.

(2022) CELLS. 11(24).

Academic Bibliography

dr. Tineke Vanderhaeghen

Comparative analysis of hepatic gene expression profiles in murine and porcine sepsis models

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression

The pig as a translational animal to explore a new concept in the treatment of sepsis, today's largest unmet medical need

The pig as a translational animal model to explore a new concept in the treatment of sepsis, today's largest unmet medical need

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Spns2/S1P : it takes two to tango with inflammation and metabolic rewiring during sepsis

Hepatic peroxisome proliferator-activated receptor alpha dysfunction in porcine septic shock

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