Pauline Depuydt

ORCID iD: 0000-0003-2956-6457

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- Conference Paper
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SOX11 as guardian of epigenetic plasticity in neuroblastoma

Bieke Decaesteker (UGent) , Amber Louwagie (UGent) , Siebe Loontiens (UGent) , Sara De Brouwer, Carolina de Carvalho Nunes (UGent) , Geertrui Denecker (UGent) , Fanny De Vloed (UGent) , Lisa Depestel (UGent) , Juliette Roels (UGent) , Karen Verboom, et al.

(2021) Advances in Neuroblastoma Research (ANR 2021), Abstracts.
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- Conference Paper
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SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Amber Louwagie (UGent) , Bieke Decaesteker (UGent) , Sara De Brouwer (UGent) , Geertrui Denecker (UGent) , Carolina de Carvalho Nunes (UGent) , Volodimir Olexiouk (UGent) , Karen Verboom, Moritz Gartlgruber, Wouter Van Loocke (UGent) , Elena Afanasyeva, et al.

(2019) Belgian Society for Human Genetics, 19th Annual meeting, Abstracts.
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- Conference Paper
- C3
SOX11 as mediator of the adrenergic cell state in NB

Bieke Decaesteker (UGent) , Amber Louwagie (UGent) , Sara De Brouwer (UGent) , Volodimir Olexiouk (UGent) , Geertrui Denecker (UGent) , Carolina de Carvalho Nunes (UGent) , Karen Verboom, Moritz Gartlgruber, Wouter Van Loocke (UGent) , Elena Afanasyeva, et al.

(2019) Pediatric Oncology and Hematology, 2nd KiTZ symposium, Abstracts.
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- Conference Paper
- C3
SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Amber Louwagie (UGent) , Bieke Decaesteker (UGent) , Carolina de Carvalho Nunes (UGent) , Geertrui Denecker (UGent) , Volodimir Olexiouk (UGent) , Karen Verboom, Moritz Gartlgruber, Wouter Van Loocke (UGent) , Elena Afanasyeva, Pauline Depuydt, et al.

(2019) OncoPoint, 7th Research seminar, Abstracts.
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- Journal Article
- A1
- open access
Data Descriptor: Meta-mining of copy number profiles of high-risk neuroblastoma tumors

Pauline Depuydt, J Koster, V Boeva, TD Hocking, Franki Speleman (UGent) , G Schleiermacher and Katleen De Preter (UGent)

(2018) SCIENTIFIC DATA. 5.
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- PhD Thesis
- open access
DNA copy number imbalances with clinical relevance in cancer : rare events in big data

Pauline Depuydt

(2018)
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- Journal Article
- A1
- open access
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , Emmy M Dolman, Wouter Van Loocke (UGent) , Moritz Gartlgruber, Carolina de Carvalho Nunes (UGent) , Fanny De Vloed (UGent) , Pauline Depuydt, Karen Verboom, et al.

(2018) NATURE COMMUNICATIONS. 9.
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- Conference Paper
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TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , Fanny De Vloed (UGent) , Moritz Gartlgruber, Pauline Depuydt, Wouter Van Loocke (UGent) , Shana Claeys (UGent) , Dries Rombaut, Siebe Loontiens (UGent) , et al.

(2018) Belgian Society for Human Genetics, 18th Annual meeting, Abstracts.
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- Conference Paper
- C3
The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , Fanny De Vloed (UGent) , Moritz Gartlgruber, Pauline Depuydt, Wouter Van Loocke (UGent) , Shana Claeys (UGent) , Dries Rombaut, Siebe Loontiens (UGent) , et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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- Conference Paper
- C3
SOX11 is a transcriptional circuit dosage sensitive transcription factor controlling SWI/SNF components

Bieke Decaesteker (UGent) , Sara De Brouwer (UGent) , Geertrui Denecker (UGent) , Fanny De Vloed (UGent) , Wouter Van Loocke (UGent) , Suzanne Vanhauwaert (UGent) , Pauline Depuydt, Moritz Gartlgruber, Jolien De Wyn, Genevieve Laureys, et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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- Conference Paper
- C3
The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Wouter Van Loocke, Moritz Gartlgruber, Pauline Depuydt, Fanny De Vloed (UGent) , Shana Claeys (UGent) , Dries Rombaut, Siebe Loontiens (UGent) , Anton Henssen, et al.

(2018) OncoPoint, 6th Research seminar, Abstracts.
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- Conference Paper
- C3
The RRM2-PHF6 complex protects neuroblastoma cells from DNA damage accumulation to install a replication stress resistance phenotype

Carolina de Carvalho Nunes (UGent) , Kaat Durinck (UGent) , Lisa Depestel (UGent) , Siebe Loontiens (UGent) , Louis Delhaye (UGent) , Sofia Zanotti (UGent) , Emmy Dolman, Aline Eggermont (UGent) , Bieke Decaesteker (UGent) , Pauline Depuydt, et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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- Journal Article
- A1
- open access
Genomic amplifications and distal 6q loss : novel markers for poor survival in high-risk neuroblastoma patients

Pauline Depuydt, Valentina Boeva, Toby D Hocking, Robrecht Cannoodt (UGent) , Inge M Ambros, Peter F Ambros, Shahab Asgharzadeh, Edward F Attiyeh, Valérie Combaret, Raffaella Defferrari, et al.

(2018) JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 110(10).
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- Journal Article
- A2
- open access
The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease

Bram De Wilde (UGent) , Anneleen Beckers (UGent) , Sven Lindner, Kristina Althoff, Katleen De Preter (UGent) , Pauline Depuydt, Pieter Mestdagh (UGent) , Tom Sante (UGent) , Steve Lefever (UGent) , Falk Hertwig, et al.

(2018) ONCOTARGET. 9(9). p.8334-8349
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- Conference Paper
- C3
The immunophenotypical fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien Bogaert (UGent) , Marieke De Bruyne (UGent) , Veronique Debacker (UGent) , Pauline Depuydt, Katleen De Preter (UGent) , Carolien Bonroy (UGent) , Jan Philippé (UGent) , Maria Bordon Cueto De Braem (UGent) , Bart Lambrecht (UGent) , Tessa Kerre (UGent) , et al.

(2017)
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- Conference Paper
- C3
Shallow whole genome sequencing on circulating cell-free DNA allows reliable non-invasive copy number profiling in neuroblastoma patients

Nadine Van Roy (UGent) , Malaïka Van der Linden (UGent) , Pauline Depuydt, Björn Menten (UGent) , Annelies Dheedene (UGent) , Charlotte Vandeputte, Jo Van Dorpe (UGent) , Genevieve Laureys (UGent) , Marjolijn Renard (UGent) , Tom Sante (UGent) , et al.

(2017) LKI Symposium, Abstracts.
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- Conference Paper
- C3
SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma

Bieke Decaesteker (UGent) , Sara De Brouwer (UGent) , Fanny De Vloed (UGent) , Geertrui Denecker, Suzanne Vanhauwaert (UGent) , Jolien De Wyn, Genevieve Laureys (UGent) , Björn Menten (UGent) , Pauline Depuydt, Patrick Reynolds, et al.

(2017) AACR annual meeting 2017. In Annual meeting of the American Association for Cancer Research : proceedings 58.
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- Conference Paper
- C3
RRM2 is an essential and druggable component of the FOXM1 driven replicative stress DNA damage response in neuroblastoma

Carolina de Carvalho Nunes (UGent) , Siebe Loontiens (UGent) , Pauline Depuydt, Suzanne Vanhauwaert (UGent) , Bieke Decaesteker (UGent) , Bram De Wilde (UGent) , Katleen De Preter (UGent) , Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , Kaat Durinck (UGent) , et al.

(2017) OncoPoint, 5th Research seminar, Abstracts.
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- Conference Paper
- C3
RRM2 is an essential and druggable component of the FOXM1 driven replicative stress DNA damage response in neuroblastoma

Carolina de Carvalho Nunes (UGent) , Siebe Loontiens (UGent) , Pauline Depuydt, Suzanne Vanhauwaert (UGent) , Bieke Decaesteker (UGent) , Bram De Wilde (UGent) , Katleen De Preter (UGent) , Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , Kaat Durinck (UGent) , et al.

(2017) Belgian Society for Human Genetics, 17th Annual meeting, Abstracts.
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- Conference Paper
- C3
The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Wouter Van Loocke (UGent) , Moritz Gartlgruber, Pauline Depuydt, Fanny De Vloed (UGent) , Shana Claeys (UGent) , Dries Rombaut, Siebe Loontiens (UGent) , Anton Henssen, et al.

(2017) Villa Joep, 7th Scientific progress meeting, Abstracts.

Academic Bibliography

Pauline Depuydt

SOX11 as guardian of epigenetic plasticity in neuroblastoma

SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

SOX11 as mediator of the adrenergic cell state in NB

SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Data Descriptor: Meta-mining of copy number profiles of high-risk neuroblastoma tumors

DNA copy number imbalances with clinical relevance in cancer : rare events in big data

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

SOX11 is a transcriptional circuit dosage sensitive transcription factor controlling SWI/SNF components

The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

The RRM2-PHF6 complex protects neuroblastoma cells from DNA damage accumulation to install a replication stress resistance phenotype

Genomic amplifications and distal 6q loss : novel markers for poor survival in high-risk neuroblastoma patients

The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease

The immunophenotypical fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Shallow whole genome sequencing on circulating cell-free DNA allows reliable non-invasive copy number profiling in neuroblastoma patients

SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma

RRM2 is an essential and druggable component of the FOXM1 driven replicative stress DNA damage response in neuroblastoma

RRM2 is an essential and druggable component of the FOXM1 driven replicative stress DNA damage response in neuroblastoma

The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

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