prof. dr. ir. Martin Guilliams

Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

Yong Chen (UGent) , Emily De Lombaerde (UGent) , Aimee-Rose Bugler-Lamb (UGent) , Zifu Zhong (UGent) , Martijn Schuijs (UGent) , Claudia Mariela Brenis Gómez (UGent) , Jamie De Baere (UGent) , Mark Gontsarik (UGent) , Heleen Lauwers (UGent) , Kim Deswarte (UGent) , et al.

(2025) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.

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Journal Article
A1
open access

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

Federico Francesco De Ponti (UGent) , Anna Bujko (UGent) , Zhuangzhuang Liu (UGent) , Paul Collins (UGent) , Sara Schuermans, Christian Maueröder (UGent) , Seraja Amstelveen (UGent) , Tinne Thoné (UGent) , Liesbet Martens (UGent) , John McKendrick (UGent) , et al.

(2025) IMMUNITY. 58(2). p.362-380

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Miscellaneous
open access

SPArrOW : a flexible, interactive and scalable pipeline for spatial transcriptomics analysis

Lotte Pollaris (UGent) , Bavo Vanneste (UGent) , Benjamin Rombaut (UGent) , Arne Defauw (UGent) , Frank Vernaillen (UGent) , Julien Mortier (UGent) , Wout Vanhenden, Liesbet Martens (UGent) , Tinne Thoné (UGent) , Jean-François Hastir (UGent) , et al.

(2024) bioRxiv.

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Journal Article
A1
open access

A prognostic molecular signature of hepatic steatosis is spatially heterogeneous and dynamic in human liver

Andrew S. Perry, Niran Hadad, Emeli Chatterjee, Maria Jimenez-Ramos, Eric Farber-Eger, Rashedeh Roshani, Lindsey K. Stolze, Michael J. Betti, Shilin Zhao, Shi Huang, et al.

(2024) CELL REPORTS MEDICINE. 5(12).

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Journal Article
A1
open access

Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells

Mohamed Amer Musrati, Benoit Stijlemans, Abdulkader Azouz, Daliya Kancheva, Sarah Mesbahi, Eva Hadadi, Els Lebegge, Leen Ali, Karen De Vlaminck, Isabelle Scheyltjens, et al.

(2024) JOURNAL OF HEPATOLOGY. 81(6). p.1023-1039

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Pattern or artifact? Interactively exploring embedding quality with TRACE

Edith Heiter (UGent) , Liesbet Martens (UGent) , Ruth Seurinck (UGent) , Martin Guilliams (UGent) , Tijl De Bie (UGent) , Yvan Saeys (UGent) and Jefrey Lijffijt (UGent)

(2024) MACHINE LEARNING AND KNOWLEDGE DISCOVERY IN DATABASES-RESEARCH TRACK AND DEMO TRACK, PT VIII, ECML PKDD 2024. In Lecture Notes in Computer Science 14948. p.379-382

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A1
open access

Tissue niche occupancy determines the contribution of fetal- versus bone-marrow-derived macrophages to IgG effector functions

Miriam Wöhner, Sarah Brechtelsbauer, Niklas Friedrich, Christof Vorsatz, Johanna Bulang, Chunguang Liang, Lena Schorr, Alain Beschin, Martin Guilliams (UGent) , Jeffrey Ravetch, et al.

(2024) CELL REPORTS. 43(2).

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Miscellaneous
open access

In vivo macrophage engineering as novel therapeutic strategy against liver metastasis

Marie Laviron (UGent) and Martin Guilliams (UGent)

(2024) TRENDS IN CANCER. 10(3). p.175-176

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Miscellaneous

Time and place : mapping human prenatal macrophages across tissues

Camille Wagner (UGent) and Martin Guilliams (UGent)

(2024) CELL RESEARCH. 34(3). p.191-192

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Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma

Bart Vanderborght (UGent) , Kevin De Muynck (UGent) , Eva Gijbels (UGent) , Sander Lefere (UGent) , Charlotte Scott (UGent) , Martin Guilliams (UGent) , Alain Beschin, Mathieu Vinken, Xavier Verhelst (UGent) , Anja Geerts (UGent) , et al.

(2023) INTERNATIONAL JOURNAL OF CANCER. 152(12). p.2615-2628

Academic Bibliography

prof. dr. ir. Martin Guilliams

Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

SPArrOW : a flexible, interactive and scalable pipeline for spatial transcriptomics analysis

A prognostic molecular signature of hepatic steatosis is spatially heterogeneous and dynamic in human liver

Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells

Pattern or artifact? Interactively exploring embedding quality with TRACE

Tissue niche occupancy determines the contribution of fetal- versus bone-marrow-derived macrophages to IgG effector functions

In vivo macrophage engineering as novel therapeutic strategy against liver metastasis

Time and place : mapping human prenatal macrophages across tissues

Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma

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