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ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation
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Viral RHIM proteins antagonise necroptosis by preventing ZBP1-induced RIPK1/RIPK3 amyloid formation in human cells
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ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation
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- Journal Article
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- open access
Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation