prof. Linos Vandekerckhove

Journal Article
A1
open access

CD4-directed nanoblades enable selective genome editing in CD4+ cells and HIV suppression in vitro and in vivo

Jolien Van Cleemput (UGent) , Maaike De Cock (UGent) , Rianne Verbeek (UGent) , Elianne Burg (UGent) , Bram Van Den Eeckhout (UGent) , Wojciech Witkowski (UGent) , Willem van Snippenberg, Zoi Stylianidou (UGent) , Emily Brugger Galetic (UGent) , Mareva Delporte (UGent) , et al.

(2026) EMBO MOLECULAR MEDICINE. 18. p.3345-3373

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Conference Paper

Making the Cut: CD4-Targeted Lipid Nanoparticles for CRISPR-Cas9-Mediated HIV Cure

Maaike De Cock (UGent) , Elianne Burg (UGent) , Sarah Gerlo (UGent) , Bruno De Geest (UGent) , Linos Vandekerckhove (UGent) and Jolien Van Cleemput (UGent)

(2026)

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Journal Article
A1
open access

HIV-1 virome profiling using HIV-PULSE to guide therapeutic and curative interventions

Sofie De Braekeleer (UGent) , Laurens Lambrechts, Liesbet Termote (UGent) , Mareva Delporte (UGent) , Kavita Mehta (UGent) , Vasiliki Matzaraki, Evy Blomme (UGent) , Philippe Lemey, Bram Vrancken, Casper Rokx, et al.

(2026) EBIOMEDICINE. 128.

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Journal Article
A1
open access

Integrase versus protease inhibitor therapy in advanced HIV disease (LAPTOP) : a multicountry, randomised, open-label, non-inferiority trial

Georg M N Behrens, Lambert Assoumou, Geoffroy Liegeon, Andrea Antinori, Rafael Micán, Francesco G Genderini, Frank A Post, Jürgen K Rockstroh, Lisa Hamzah, Pere Domingo, et al.

(2026) LANCET INFECTIOUS DISEASES. 26(5). p.510-521

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Miscellaneous

The imperative for increased investment for an HIV cure

Remko van Leeuwen, Françoise Barré-Sinoussi, Michaela Müller-Trutwin, Asier Sáez-Cirión, Monique Nijhuis, Sharon R Lewin, Thumbi Ndung'u, Florence Riako-Anam, Mitchell Warren, Izukanji Sikazwe, et al.

(2025) LANCET HIV. 12(10). p.e671-e673

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Journal Article
A1
open access

Evolution of the HIV-1 integration site landscape and inducible reservoir in early-treated people

Tine Struyve (UGent) , Marion Pardons (UGent) , Jozefien De Clercq (UGent) , Liesbet Termote (UGent) , Laurens Lambrechts, Ytse Noppe (UGent) , Mathias Lichterfeld, Sofie Rutsaert (UGent) and Linos Vandekerckhove (UGent)

(2025) PLOS PATHOGENS. 21(11).

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Miscellaneous
open access

Advances in human myeloid-engrafting NSG-SGM3 and MISTRG mice

Hannah Stocks (UGent) , Jolien Van Cleemput (UGent) , Linos Vandekerckhove (UGent) and Andy Wullaert (UGent)

(2025) TRENDS IN IMMUNOLOGY. 46(10). p.662-665

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Virulent HIV-1B : clinical challenges and proteomic insights

Kavita Mehta (UGent) , Mareva Delporte (UGent) , Victoria Rios Vazquez, Marc J. T Blaauw, Louise E. van Eekeren, Albert L. Groenendijk, Wilhelm A Vos, Evy Blomme (UGent) , Sarah Gerlo (UGent) , Bram Vrancken, et al.

(2025) Abstract eBook 32nd Conference on Retroviruses and Opportunistic Infections (CROI 2025). p.79-79

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Journal Article
A1
open access

Blood and tissue HIV-1 reservoirs display plasticity and lack of compartmentalization in virally suppressed people

Marion Pardons (UGent) , Laurens Lambrechts, Ytse Noppe (UGent) , Liesbet Termote (UGent) , Sofie De Braekeleer (UGent) , Jerel Vega, Ellen Van Gulck, Sarah Gerlo (UGent) and Linos Vandekerckhove (UGent)

(2025) NATURE COMMUNICATIONS. 16(1).

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Journal Article
A1
open access

Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy : an individual data-based meta-analysis of 24 prospective studies

Jesper D. Gunst, Jesal Gohil, Johanthan Z. Li, Ronald J. Bosch, Andrea White, Catherine Seamon, Tae-Wook Chun, Beatriz Mothe, Kathleen Gittens, Lauren Praiss, et al.

(2025) NATURE COMMUNICATIONS. 16(1).

Academic Bibliography

prof. Linos Vandekerckhove

CD4-directed nanoblades enable selective genome editing in CD4+ cells and HIV suppression in vitro and in vivo

Making the Cut: CD4-Targeted Lipid Nanoparticles for CRISPR-Cas9-Mediated HIV Cure

HIV-1 virome profiling using HIV-PULSE to guide therapeutic and curative interventions

Integrase versus protease inhibitor therapy in advanced HIV disease (LAPTOP) : a multicountry, randomised, open-label, non-inferiority trial

The imperative for increased investment for an HIV cure

Evolution of the HIV-1 integration site landscape and inducible reservoir in early-treated people

Advances in human myeloid-engrafting NSG-SGM3 and MISTRG mice

Virulent HIV-1B : clinical challenges and proteomic insights

Blood and tissue HIV-1 reservoirs display plasticity and lack of compartmentalization in virally suppressed people

Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy : an individual data-based meta-analysis of 24 prospective studies

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