Ria Roelandt
work address
Technologiepark Zwijnaarde 927, VIB
9052 Zwijnaarde
9052 Zwijnaarde
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- 2017
- When PERK inhibitors turn out to be new potent RIPK1 inhibitors : critical issues on the specificity and use of GSK2606414 and GSK2656157
- 2016
- Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay
- 2014
- Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability
- MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates
- Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
- Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock
- 2012
- Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
- 2011
- Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin
- cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)
- 2010
- Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria