prof. dr. Wim Derave
- ORCID iD
- 0000-0002-2225-5587
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The effects of residual dipolar coupling on carnosine in proton muscle spectra
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In professional football the decline in high‐intensity running activities from first to second half is more pronounced in players with a fast muscle typology
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Match running performance in Australian football is related to muscle fiber typology
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Extensive profiling of histidine‐containing dipeptides reveals species‐ and tissue‐specific distribution and metabolism in mice, rats, and humans
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Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis
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- Journal Article
- A1
- open access
Acute balenine supplementation in humans as a natural carnosinase-resistant alternative to carnosine
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- Journal Article
- A1
- open access
Muscle typology influences the number of repetitions to failure during resistance training
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- Journal Article
- A1
- open access
Can muscle typology explain the inter‐individual variability in resistance training adaptations?
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- Journal Article
- A1
- open access
No effect of acute balenine supplementation on maximal and submaximal exercise performance in recreational cyclists
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Influence of muscle fiber typology on leg muscle hypertrophy and dynamic strength gains after 10 weeks of resistance training to failure
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Influence of muscle fiber typology on leg muscle hypertrophy and dynamic strength gains after 10 weeks of resistance training to failure
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Insulin sensitization following a single exercise bout is uncoupled to glycogen in human skeletal muscle : a meta-analysis of 13 single-center human studies
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Muscle fiber typology in national level football and its influence on in-game fatigue
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- Journal Article
- A1
- open access
Efficacy of 12 weeks oral beta‐alanine supplementation in patients with chronic obstructive pulmonary disease : a double‐blind, randomized, placebo‐controlled trial
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- Journal Article
- A1
- open access
Motor unit fatigability following chronic carnosine supplementation in aged rats
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Is insulin resistance the heavy toll for speed? Comment
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- Journal Article
- A1
- open access
The muscle typology of elite and world-class swimmers
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- Journal Article
- A1
- open access
The ergogenic effect of acute carnosine and anserine supplementation : dosing, timing, and underlying mechanism
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- Journal Article
- A1
- open access
Muscle fibre typology as a novel risk factor for hamstring strain injuries in professional football (soccer) : a prospective cohort study
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The ergogenicity of acute carnosine and anserine supplementation : the search for an underlying mechanism
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Carnosine, oxidative and carbonyl stress, antioxidants, and muscle fiber characteristics of quadriceps muscle of patients with COPD
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- Journal Article
- A1
- open access
Reply to da Eira Silva et al.
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- Journal Article
- A1
- open access
Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation
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Carnosine and skeletal muscle dysfunction in a rodent multiple sclerosis model
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- Book
- open access
Myotypes : the relevance of muscle fiber typology in sports
(2021) -
- Journal Article
- A1
- open access
Monomeric CRP is elevated in patients with COPD compared to non-COPD control persons
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- Journal Article
- A1
- open access
Sex-specific maturation of muscle metabolites carnosine, creatine and carnitine over puberty : a longitudinal follow-up study
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Acute preexercise supplementation of combined carnosine and anserine enhances initial maximal power of Wingate tests in humans
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CORP : quantification of human skeletal muscle carnosine concentration by proton magnetic resonance spectroscopy
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Relationships between lower limb muscle characteristics and force-velocity profiles derived during sprinting and jumping
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Muscle fiber typology and its association with start and turn performance in elite swimmers
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- Journal Article
- A1
- open access
Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders
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The influence of muscle fiber typology on the pacing strategy of 200-m freestyle swimmers
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Oral anserine supplementation does not attenuate type-2 diabetes or diabetic nephropathy in BTBR ob/ob mice
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- Journal Article
- A1
- open access
Determinants of performance in paced and maximal 800-m running time trials
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- Journal Article
- A1
- open access
A potential role for fructosamine-3-kinase in cataract treatment
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Myokines, de boodschappers van de spieren
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W' recovery kinetics following exhaustion : a two-phase exponential process influenced by aerobic fitness
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- Journal Article
- A1
- open access
Ergogenic effect of pre-exercise chicken broth ingestion on a high-intensity cycling time-trial
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- Journal Article
- A1
- open access
Traditional high jump Gusimbuka Urukiramende : could early 20th century African athletes beat Olympic champions?
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- Journal Article
- A2
- open access
Relationship between duty factor and external forces in slow recreational runners
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- Journal Article
- A1
- open access
Histamine H1 and H2 receptors are essential transducers of the integrative exercise training response in humans
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Determinants of last lap speed in paced and maximal 1500-m time trials
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- Journal Article
- A1
- open access
Muscle typology of world-class cyclists across various disciplines and events
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- Journal Article
- A1
- open access
Proton magnetic resonance spectroscopy in skeletal muscle : experts' consensus recommendations
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- Conference Paper
- C3
- open access
Muscle fiber typologies in elite cycling disciplines
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- Conference Paper
- C3
- open access
Is muscle typology in young talented track and field athletes a predictor for adult success?
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The role of alanine glyoxylate transaminase-2 (agxt2) in β-alanine and carnosine metabolism of healthy mice and humans
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- Journal Article
- A1
- open access
Carnosinase-1 overexpression, but not aerobic exercise training, affects the development of diabetic nephropathy in BTBR ob/ob mice
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- Journal Article
- A1
- open access
Beta-alanine supplementation in patients with COPD receiving non-linear periodised exercise training or neuromuscular electrical stimulation : protocol of two randomised, double-blind, placebo-controlled trials
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- Journal Article
- A1
- open access
Muscle fiber typology is associated with the incidence of overreaching in response to overload training
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- Journal Article
- A1
- open access
Muscle fiber typology substantially influences time to recover from high-intensity exercise
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- Conference Paper
- C3
- open access
Grounded runners experience less severe ground reaction forces compared to runners who run with a flight phase
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- Conference Paper
- C3
- open access
Running profiles of recreational distance runners : race, training, spatiotemporal and anthropometrical characteristics
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Fragmented dosing of β-alanine induces a body weight-independent pharmacokinetic response
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- Conference Paper
- C3
- open access
Muscle typologies and talent transfer in elite cycling
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Non-invasive estimation of muscle fiber typology in various disciplines of professional cycling
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- Conference Paper
- C3
- open access
Acute carnosine and anserine supplementation as a novel ergogenic strategy for high-intensity exercise
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Differences in muscle histidine‐containing dipeptides in broilers
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- Journal Article
- A1
- open access
Fragmented dosing of β-alanine induces a body weight-independent pharmacokinetic response
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- Journal Article
- A1
- open access
Acute aerobic exercise leads to increased plasma levels of R- and S-β-aminoisobutyric acid in humans
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Personalized sport and exercise nutrition
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- Journal Article
- A1
- open access
Predicting and testing bioavailability of magnesium supplements
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Eight weeks of static apnea training increases spleen volume but not acute spleen contraction
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Carnosinase-1 overexpression, but not aerobic exercise training, affects the development of advanced diabetic nephropathy
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Sports foods and dietary supplements for optimal function and performance enhancement in track-and-field athletes
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An update on carnosine and anserine research
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Grounded running reduces musculoskeletal loading
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Development and validation of a sensitive LC-MS/MS assay for the quantification of anserine in human plasma and urine and its application to pharmacokinetic study
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- Conference Paper
- C3
- open access
Instructed grounded running reduces musculoskeletal loading
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- Conference Paper
- C3
- open access
Acute exercise leads to increased levels of plasma carnosine and carnosine-acrolein conjugates in humans
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The acute exercise metabolism of the so-called myokine BAIBA
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Exercise alters and β-alanine combined with exercise augments histidyl dipeptide levels and scavenges lipid peroxidation products in human skeletal muscle
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- Conference Paper
- C3
- open access
The impact of an eight week apnea training program on spleen volume and hematological values
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- Journal Article
- A1
- open access
Pharmacokinetics of β-alanine using different dosing strategies
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Personalised nutrition : the effect of an AGXT2 polymorphism on beta-alanine pharmacokinetic response
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The acute exercise metabolism of the so-called myokine BAIBA
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Changing to a vegetarian diet reduces the body creatine pool in omnivorous women, but appears not to affect carnitine and carnosine homeostasis : a randomised trial
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- Journal Article
- A1
- open access
Bi-articular knee-ankle-foot exoskeleton produces higher metabolic cost reduction than weight-matched mono-articular exoskeleton
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Muscle carnosine in experimental autoimmune encephalomyelitis and multiple sclerosis
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- Journal Article
- A1
- open access
Changes in lower limb muscle function and muscle mass following exercise-based interventions in patients with chronic obstructive pulmonary disease : a review of the English-language literature
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Acute exercise leads to an increased urinary excretion of carnosine and carnosine-acrolein products in humans
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- Conference Paper
- C3
- open access
The protective effect of exercise on diabetic nephropathy : the role of histidine-containing dipeptides
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- Conference Paper
- C3
- open access
The protective effect of exercise on diabetic nephropathy : the role of histidyl containing dipeptides
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Can non-invasively determined muscle typology predict fatigue and recovery profile?
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- Journal Article
- A1
- open access
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
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AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model
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Effects of histidine and β-alanine supplementation on human muscle carnosine storage
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Exoskeleton plantarflexion assistance for elderly
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Cyclic movement frequency is associated with muscle typology in athletes
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Discriminant musculo-skeletal leg characteristics between sprint and endurance elite Caucasian runners
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The effect of acute exercise and serum carnosinase on circulating and muscle histidine-containing dipeptides in mice
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The effect of acute exercise and serum carnosinase on circulating and muscle histidine-containing dipeptides in mice
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Fixing the metabolic leak in the inefficient muscle carnosine loading scheme by oral beta-alanine supplementation
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The better the distance runner, the more slow-twitch muscle typology?
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The impact of an 8-week apnea training period on splenic volume and blood values
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Athlome Project Consortium : a concerted effort to discover genomic and other 'omic' markers of athletic performance
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Effects of carnosine supplementation on glucose metabolism : pilot clinical trial
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Carnosine and anserine homeostasis in skeletal muscle and heart is controlled by β-alanine transamination
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Role of histidyl dipeptides in contractile function of fast and slow motor units in rat skeletal muscle
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Changes in structural and metabolic muscle characteristics following exercise-based interventions in patients with COPD : a systematic review
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Possible influences on the interpretation of functional domain (FD) near-infrared spectroscopy (NIRS): an explorative study
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- Journal Article
- A2
- open access
Carnosine content in skeletal muscle is dependent on vitamin B6 status in rats
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Muscle carnosine and anserine content depend on vitamin B6 status in rats
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Inhibiting beta-alanine transamination : a way to promote muscle histidine-containing dipeptide loading in mice?
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Bèta-alanine en sportprestaties
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Gusimbuka Urukiramende : were African high jumpers the real world champions?
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Carnosine and anserine in skeletal muscles and heart are dependent on vitamin B6 status
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Carnosine supplementation improved insulin resistance in overweight and obese humans
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Plasma carnosine, but not muscle carnosine, attenuates high-fat diet-induced metabolic stress
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Aerobic and resistance training do not influence plasma carnosinase content or activity in type 2 diabetes
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- Journal Article
- A1
- open access
Muscle carnosine is associated with cardiometabolic risk factors in humans
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Histidine-containing dipeptides
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Human skeletal muscle carnosine and its function: a focus on homeostasis, muscle contractility and pH
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- Journal Article
- A2
- open access
Exercise training and beta-alanine-induced muscle carnosine loading
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- Journal Article
- A1
- open access
Muscle histidine-containing dipeptides are elevated by glucose intolerance in both rodents and men
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β-Alanine does not act through branched-chain amino acid catabolism in carp, a species with low muscular carnosine storage
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An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model
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Effects of tail suspension on serum testosterone and molecular targets regulating muscle mass
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Beta-alanine supplementation, muscle carnosine and exercise performance
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Uphill walking with a simple exoskeleton: plantarflexion assistance leads to proximal adaptations
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Effect of beta-alanine and histidine supplementation on muscle carnosine loading
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Does carnosine play a role in obesity related insulin resistance in humans?
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Prediabetes and type 2 diabetes are associated with increased content of dipeptide carnosine in human skeletal muscle
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- Journal Article
- A1
- open access
Enhancing performance during inclined loaded walking with a powered ankle-foot exoskeleton
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Chaperone nanobodies protect gelsolin against MT1-MMP degradation and alleviate amyloid burden in the gelsolin amyloidosis mouse model
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Dietary supplements for aquatic sports
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- Journal Article
- A1
- open access
Doubling of muscle carnosine concentration does not improve laboratory 1-hr cycling time trial performance
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The beta-alanine dose for maintaining moderately elevated muscle carnosine levels
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Androgenic and estrogenic regulation of Atrogin-1, MuRF1 and myostatin expression in different muscle types of male mice
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- Journal Article
- A1
- open access
Genetic variations in the androgen receptor are associated with steroid concentrations and anthropometrics but not with muscle mass in healthy young men
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Muscle carnosine loading by beta-alanine supplementation is more pronounced in trained vs. untrained muscles
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Does low serum carnosinase activity favor high-intensity exercise capacity?
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Does low serum canrosinase activity favour high-intensity exercise capacity?
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Use of β-alanine as an ergogenic aid
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Physiology and pathophysiology of carnosine
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Dietary β-alanine does not affect amino acid metabolism under mild chronic elevated temperature in carp
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Meal and beta-alanine co-ingestion enhances muscle carnosine loading
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Adaptation to walking with an exoskeleton that assists ankle extension
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- Conference Paper
- C3
- open access
A simple exoskeleton that assists plantarflexion can reduce the metabolic cost of human walking
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- Conference Paper
- C1
- open access
Powered biarticular exoskeleton with gastrocnemius mimicking configuration produces higher reduction in metabolic cost than soleus mimicking configuration
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Gene expression of carnosine-related enzymes and transporters in skeletal muscle
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- Journal Article
- A1
- open access
A simple exoskeleton that assists plantarflexion can reduce the metabolic cost of human walking
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Effect of beta-alanine and carnosine supplementation on muscle contractility in mice
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- Conference Paper
- C3
- open access
Exoskeleton with optimal timing reduces metabolic cost due to EMG reduction
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Low plasma carnosinase activity promotes carnosinemia after carnosine ingestion in humans
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Reduced muscle carnosine content in type 2, but not in type 1
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The influence of sex, age and heritability on human skeletal muscle carnosine content
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Carnosine in exercise and disease: introduction to the international congress held at Ghent University, Belgium, July 2011
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- Conference Paper
- C3
- open access
Feasibility of an exoskeleton powered by eccentric joint work for reducing walking metabolic cost
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A simple ankle-foot exoskeleton can lower the metabolic cost of walking
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- Conference Paper
- C3
- open access
Een exoskelet voor fundamenteel onderzoek van de menselijke gang
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Effects of sprint training combined with vegetarian or mixed diet on muscle carnosine content and buffering capacity
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- Journal Article
- A1
- open access
A new method for non-invasive estimation of human muscle fiber type composition
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Vegetarianism, female gender and increasing age, but not CNDP1 genotype, are associated with reduced muscle carnosine levels in humans
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- Journal Article
- A1
- open access
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance-Part 20
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- Journal Article
- A1
- open access
Physical fitness in morbidly obese patients: effect of gastric bypass surgery and exercise training
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Kinesiology in flanders: brain drain versus brain gain: verslag symposium Vereniging voor Kinesiologie
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Invloed van beta-alanine-suppletie op spiercarnosine en sportprestaties
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Important role of muscle carnosine in rowing performance
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- Journal Article
- A1
- open access
Muscle carnosine metabolism and β-alanine supplementation in relation to exercise and training
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beta-Alanine supplementation reduces acidosis but not oxygen uptake response during high-intensity cycling exercise
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Mouth rinse but not ingestion of a carbohydrate solution improves 1-h cycle time trial performance
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De zin en onzin van voedingssupplementen bij sportbeoefening
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- Journal Article
- A4
- open access
Het gebruik van voedingssupplementen bij jongeren
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Beware of the pickle: health effects of nitrate intake
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Dietary arginine supplementation speeds pulmonary VO2 kinetics during cycle exercise
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Carnosine loading and washout in human skeletal muscles
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Creatine supplementation augments skeletal muscle carnosine content in senescence-accelerated mice (SAMP8)
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Effect of training in the fasted state on metabolic responses during exercise with carbohydrate intake
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- Journal Article
- A1
- open access
Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of akt phosphorylation
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1H MRS as evaluation tool of the effects of beta-alanine supplementation on the muscle carnosine content in soleus and gastrocnemius of 400m sprinters
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- PhD Thesis
- open access
EXERCISE EFFECTS ON MUSCLE GLUCOSE UPTAKE AND INSULIN ACTION
(2008) -
Medicijnen worden doping... en omgekeerd!: het creatineverhaal
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Bewegen in extreme condities
Wim Derave (UGent) and Renaat Philippaerts (UGent)(2007) -
Ergogenic effects of creatine in sports and rehabilitation.
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Absolute quantification of carnosine in human calf muscle by proton magnetic resonance spectroscopy
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Effects of post-absorptive and postprandial exercise on glucoregulation in metabolic syndrome
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beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters
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Fiber type-specific muscle glycogen sparing due to carbohydrate intake before and during exercise
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Oral creatine supplementation in humans does not elevate urinary excretion of the carcinogen N-nitrososarcosine
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Electrolysis stimulates creatine transport and transporter cell surface expression in incubated mouse skeletal muscle: potential role of ROS
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Human skeletal muscle atrophy in amyotrophic lateral sclerosis reveals a reduction in Akt and an increase in atrogin-1
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AMP kinase expression and activity in human skeletal muscle: effects of immobilization, retraining, and creatine supplementation
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Exercise in the fasted state facilitates fibre type-specific intramyocellular lipid breakdown and stimulates glycogen resynthesis in humans
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No effects of lifelong creatine supplementation on sarcopenia in senescence-accelerated mice (SAMP8)
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Soleus muscles of SAMP8 mice provide an accelerated model of skeletal muscle senescence
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Treadmill exercise negatively affects visual contribution to static postural stability
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Treadmill exercise negatively affects visual contribution to static postural stability
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Fysieke activiteit, insulinegevoeligheid en type-2 diabetes
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Glycogen synthase localization and activity in rat skeletal muscle is strongly dependent on glycogen content.
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Dissociation of AMP-activated protein kinase activation and glucose transport in contracting slow-twitch muscle
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Regeling van skeletspierdoorbloeding tijdens inspanning
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De regeling van glucose opname in de skeletspier: intracellulaire mechanismen
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Carbohydrate availability affects ammonemia during exercise after beta(2)-adrenergic blockade.
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Pro- and macroglycogenolysis in contracting rat skeletal muscle.
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Effect of branched-chain amino acids (BCAA), glucose, and glucose plus BCAA on endurance performance in rats
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Role of adenosine in regulating glucose uptake during contractions and hypoxia in rat skeletal muscle.
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Contraction-stimulated muscle glucose transport and GLUT-4 surface content are dependent on glycogen content.
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The influence of exercise and dehydration on postural stability.
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Gender differences in blood ammonia response during exercise.