prof. dr. Christophe Ampe
- ORCID iD
- 0000-0002-8554-3594
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- Journal Article
- A1
- open access
Acid‐resistant BODIPY amino acids for peptide‐based fluorescence imaging of GPR54 receptors in pancreatic islets
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- Journal Article
- A1
- open access
Multisite assessment of reproducibility in high‐content cell migration imaging data
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- Journal Article
- A1
- open access
Innovative mouse models for the tumor suppressor activity of protocadherin-10 isoforms
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Cancer type-specific alterations in actin genes : worth a closer look?
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Furan warheads for covalent trapping of weak protein-protein interactions : cross-linking of thymosin β4 to actin
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Time for rethinking the different β‐actin transgenic mouse models?
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- Journal Article
- A1
- open access
Community standards for open cell migration data
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- Journal Article
- A1
- open access
Prevalence of cytoplasmic actin mutations in diffuse large B-cell lymphoma and multiple myeloma : a functional assessment based on actin three-dimensional structures
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Cytoplasmic actin mutations
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A new evolutionary model for the vertebrate actin family including two novel groups
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Intercalated discs : specialized cytoskeletal anchors in cardiac muscle
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Analysis of invasion dynamics of matrix-embedded cells in a multisample format
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Exploration of CLP antitumor potential
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Influence of CLP structure on antitumor potential
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An emerging link between LIM domain proteins and nuclear receptors
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- Journal Article
- A1
- open access
Combination of EGFR inhibitor lapatinib and MET inhibitor foretinib inhibits migration of triple negative breast cancer cell lines
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Surveillance of myelodysplastic syndrome via migration analyses of blood neutrophils : a potential prognostic tool
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Concerted biophysical and biological evaluation of Pseudomonas lipopeptides as a premise to unlock their application potential
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- Journal Article
- A1
- open access
The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions
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- Journal Article
- A1
- open access
An end-to-end software solution for the analysis of high-throughput single-cell migration data
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Expanding the interactome of TES by exploiting TES modules with different subcellular localizations
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Cross-linking furan-modified kisspeptin-10 to the KISS receptor
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Mammalian actins : isoform-specific functions and diseases
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An actomyosin-like cytoskeleton in the cyanobiont (Nosctoc sp.) of Peltigera canina
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The unfolded protein response underlies microenvironmental stress-induced phenotype switching leading to stemness and chemoresistance in human hepatocellular carcinoma
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Furan-based crosslinking in situ : seizing ligand-receptor complexes in the act
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- Journal Article
- A1
- open access
Taking aim at moving targets in computational cell migration
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- Journal Article
- A1
- open access
Delineating the Tes interaction site in zyxin and studying cellular effects of its disruption
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- Journal Article
- A1
- open access
Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure
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Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure
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Active invadopodia of mesenchymally migrating cancer cells contain both β and γ cytoplasmic actin isoforms
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An open data ecosystem for cell migration research
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- Journal Article
- A1
- open access
β-Agonists selectively modulate proinflammatory gene expression in skeletal muscle cells via non-canonical nuclear crosstalk mechanisms
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- Journal Article
- A1
- open access
Beta-actin is required for proper mouse neural crest ontogeny
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p210bcr-abl induces amoeboid motility by recruiting ADF/destrin through RhoA/ROCK1
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Alphaherpesviral US3 kinase induces cofilin dephosphorylation to reorganize the actin cytoskeleton
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- Journal Article
- A1
- open access
Beta-actin is involved in modulating erythropoiesis during development by fine-tuning Gata2 expression levels
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Biophysical approaches for investigation of the cytoskeleton: a special issue stemming from research presented at the 2012 ECF meeting: a FEBS/EMBO workshop lecture course in Pécs, Hungary
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CellMissy: a tool for management, storage and analysis of cell migration data produced in wound healing-like assays
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CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP
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β-actin knock-out mouse embryonic fibroblasts show increased expression of LIM-, CH-, EFh-domain containing proteins with predicted common upstream regulators
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- Journal Article
- A1
- open access
The XTT cell proliferation assay applied to cell layers embedded in three-dimensional matrix
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Phosphosite conservation in single domain orthologs versus paralogs: a way to combine differential regulation with redundant core functions
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Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity
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- Conference Paper
- C3
- open access
The US3 kinase of pseudorabies virus leads to activation of the actin regulator cofilin to induce actin cytoskeleton changes
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Actin and actin filaments
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A QUICK screen for Lrrk2 interaction partners: leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics
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Intermolecular interaction studies using small volumes
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- Journal Article
- A1
- open access
Identification and expression analysis of splice variants of mouse enabled homologue during development and in adult tissues
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Algemene biochemie: functionele bouwstenen van het leven
(2009) -
alpha-Skeletal Muscle Actin Mutants Causing Different Congenital Myopathies Induce Similar Cytoskeletal Defects in Cell Line Cultures
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The Mouse Thymosin Beta15 Gene Family Displays Unique Complexity and Encodes A Functional Thymosin Repeat
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Impaired neural crest migration contributes to midgestation lethality of beta-actin knock-out mouse
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The Interaction of Proline-Rich Ligands with Profilin Probed with an Enzyme-Linked Immunosorbent Assay
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alpha-Skeletal muscle actin nemaline myopathy mutants cause cell death in cultured muscle cells.
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- Journal Article
- A2
- open access
Phenotypes induced by NM causing α-skeletal muscle actin mutants in fibroblasts, Sol 8 myoblasts and myotubes
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Actin isoform expression patterns during mammalian development and in pathology: insights from mouse models
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An integrative simulation model linking major biochemical reactions of actin-polymerization to structural properties of actin filaments
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Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering
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Ins and outs of ADF/cofilin activity and regulation
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S100B Expression in forensic brain trauma fatalities: a valuable tool?
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Predicting the effect of a point mutation on a protein fold: The villin and advillin headpieces and their Pro62Ala mutants
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On the origin and evolution of vertebrate and viral profilins
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Structural and Functional Implications of the PXWK-motif in HeadPiece Domains
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Structural and Functional Implicationof the PXWK-motif in HeadPiece Domains
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Structure-function relationship of actin binding modules studied by NMR
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Atomistic Prediction of the structure of the Advillin headpiece and its Pro62Ala mutant
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Functional and profiling studies prove that prostate cancer upregulated neuroblastoma thymosin beta is the true human homologue of rat thymosin beta 15
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The LIM domains of WLIM1 define a new class of actin bundling modules
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- Journal Article
- A1
- open access
Cell_motility : a cross-platform, open source application for the study of cell motion paths
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Multirepeat beta-thymosins
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- Journal Article
- A1
- open access
Tobacco WLIM1 is a novel F-actin binding protein involved in actin cytoskeleton remodeling
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THE ROLE OF PRO62 AND TRP64 FOR HEADPIECE STABILITY
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The Role of Pro62 and Trp64 for HeadPiece Stability
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Caenorhabditis elegans expresses three functional profilins in a tissue-specific manner
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Actin interacts with CCT via discrete binding sites: A binding transition-release model for CCT-mediated actin folding
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Profilin-I-ligand interactions influence various aspects of neuronal differentiation
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Identification of the PXW sequence as a structural gatekeeper of the headpiece C-terminal subdomain fold
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Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement
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Reducing mutational bias in random protein libraries
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Rescue and in situ selection and evaluation (RISE): A method for high-throughput panning of phage display libraries
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A role for complexes of survival of motor neurons (SNM) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells
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The actin cytoskeleton in normal and pathological cell motility
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The folding pathways of actin and tubulins, mechanism of and recognition by the eukaryotic chaperones prefoldin and CCT
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STRUCTURE, FUNCTION AND FOLD STABILITY OF THE HEADPIECE C-TERMINAL SUBDOMAIN
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Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding
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TetraThymosin beta is required for actin dynamics in Caenorhabditis elegans and acts via functionally different actin-binding repeats
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Structural plasticity of functional actin: Pictures of actin binding protein and polymer interfaces (vol 11, pg 1279, 2004)
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Solution structures of the C-terminal headpiece subdomains of human villin and advillin, evaluation of headpiece F-actin-binding requirements
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Myopathy mutations in alpha-skeletal-muscle actin cause a range of molecular defects
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A phage display-based method for determination of relative affinities of mutants - Application to the actin-binding motifs in thymosin beta 4 and the villin headpiece
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Structural plasticity of functional actin: Pictures of actin binding protein and polymer interfaces
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- Journal Article
- A1
- open access
Mutational analysis of human profilin I reveals a second PI(4,5)-P2 binding site neighbouring the poly(L-proline) binding site
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Normalization of nomenclature for peptide motifs as ligands of modular protein domains.
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Actin and actin filaments
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The competitive interaction of actin and PIP2 with actophorin is based on overlapping target sites : design of a gain-of-function mutant
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Profilin II is alternatively spliced, resulting in profilin isoforms that are differentially expressed and have distinct biochemical properties
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Structural requirements for thymosin beta 4 in its contact with actin - An NMR-analysis of thymosin beta 4 mutants in solution and correlation with their biological activity.
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cAMP-dependent protein kinase phosphorylation of EVL, a mena/VASP relative, regulates its interaction with actin and SH3 domains.
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Effects of natural mutations in lecithin:cholesterol acyltransferase on the enzyme structure and activity