prof. dr. apr. Serge Van Calenbergh
- ORCID iD
- 0000-0002-4201-1264
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Dual N6/C7-substituted 7-deazapurine and tricyclic ribonucleosides with affinity for G protein-coupled receptors
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- Journal Article
- A1
- open access
3D-printed wound dressings containing a fosmidomycin-derivative prevent Acinetobacter baumannii biofilm formation
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- Journal Article
- A1
- open access
Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine.
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- Journal Article
- A1
- open access
Study of G protein-coupled receptors dimerization : from bivalent ligands to drug-like small molecules
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- Journal Article
- A1
- open access
Cloning and characterization of Trypanosoma congolense and T. vivax nucleoside transporters reveal the potential of P1-type carriers for the discovery of broad-spectrum nucleoside-based therapeutics against animal African trypanosomiasis
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- Journal Article
- A1
- open access
Acyloxymethyl and alkoxycarbonyloxymethyl prodrugs of a fosmidomycin surrogate as antimalarial and antibacterial agents
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- Journal Article
- A1
- open access
Targeted AURKA degradation : towards new therapeutic agents for neuroblastoma
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- Journal Article
- A1
- open access
Phenotypic evaluation of nucleoside analogues against Trypanosoma cruzi infection : in vitro and in vivo approaches
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- Journal Article
- A1
- open access
Exploration of 6-methyl-7-(hetero)aryl-7-deazapurine ribonucleosides as antileishmanial agents
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- Journal Article
- A1
- open access
Nucleoside analogues for the treatment of animal trypanosomiasis
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- Journal Article
- A1
- open access
A Toxoplasma gondii oxopurine transporter binds nucleobases and nucleosides using different binding modes
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- Journal Article
- A1
- open access
Ex vivo feedback control of neurotransmission using a photocaged adenosine A1 receptor agonist
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Phenethyl-4-ANPP : a marginally active byproduct suggesting a switch in illicit fentanyl synthesis routes
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- Journal Article
- A1
- open access
N6-modification of 7-deazapurine nucleoside analogues as anti-Trypanosoma cruzi and anti-Leishmania agents : structure-activity relationship exploration and in vivo evaluation
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- Journal Article
- A2
- open access
7-Aryl-7-deazapurine 3 '-deoxyribonucleoside derivative as a novel lead for Chagas' disease therapy : in vitro and in vivo pharmacology
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- Journal Article
- A1
- open access
6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents
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Analytical characterization of 'etonitazepyne', a new pyrrolidinyl‐containing 2‐benzylbenzimidazole opioid sold online
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- Journal Article
- A1
- open access
Deazapurine nucleoside analogues for the treatment of Trichomonas vaginalis
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Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors
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- Conference Paper
- C3
- open access
Optical control of excitatory transmission in hippocampal slices with photoactive adenosine A1 receptor agonist
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- Conference Paper
- C3
- open access
Feedback control of CA1 excitability in hippocampal slices with a photoactive adenosine A1 receptor agonist
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- Conference Paper
- C3
- open access
Optical control of excitatory transmission in hippocampal slices with photoactive adenosine A1 receptor agonist
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- Journal Article
- A2
- open access
Sustainability in drug discovery
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Discovery of a true bivalent dopamine D2 receptor agonist
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- Journal Article
- A1
- open access
Synthesis and evaluation of a collection of purine-like C-nucleosides as antikinetoplastid agents
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- Journal Article
- A1
- open access
4E interacting protein as a potential novel drug target for nucleoside analogues in Trypanosoma brucei
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Revisiting pyrazolo[3,4-d]pyrimidine nucleosides as anti-trypanosoma cruzi and antileishmanial agents
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- Journal Article
- A1
- open access
Synthesis and evaluation of 3′-fluorinated 7-deazapurine nucleosides as antikinetoplastid agents
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6‐methyl‐7‐aryl‐7‐deazapurine nucleosides as anti‐trypanosoma cruzi agents : structure‐activity relationship and in vivo efficacy
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- Journal Article
- A1
- open access
RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia
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2-((3,5-Dinitrobenzyl)thio)quinazolinones : potent antimycobacterial agents activated by deazaflavin (F420)-dependent nitroreductase (Ddn)
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- Journal Article
- A1
- open access
Report on a new opioid NPS : chemical and in vitro functional characterization of a structural isomer of the MT-45 derivative diphenpipenol
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Sydnone ribosides as a platform for the synthesis of pyrazole C-nucleosides : a unified synthesis of formycin B and pyrazofurin
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Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner
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- Journal Article
- A1
- open access
Design, synthesis and characterization of a new series of fluorescent metabotropic glutamate receptor type 5 negative allosteric modulators
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Synthetic rhamnose glycopolymer cell-surface receptor for endogenous antibody recruitment
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- Journal Article
- A1
- open access
Synthesis and structure-activity relationships of cerebroside analogues as substrates of cerebroside sulphotransferase and discovery of a competitive inhibitor
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- Journal Article
- A1
- open access
First report on brorphine : the next opioid on the deadly new psychoactive substance horizon?
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- Journal Article
- A1
- open access
Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents
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- Journal Article
- A1
- open access
1-(1-Arylethylpiperidin-4-yl)thymine analogs as antimycobacterial TMPK inhibitors
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- Journal Article
- A1
- open access
Structure-activity relationship exploration of 3’-deoxy-7-deazapurine nucleoside analogues as anti-Trypanosoma brucei agents
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- Journal Article
- A1
- open access
Radiosynthesis, in vitro and preliminary biological evaluation of [F-18]2-amino-4-((2-((3-fluorobenzyl)oxy)benzyl)(2-((3-(fluoromethyl)benzyl)oxy)benzyl)amino) butanoic acid, a novel alanine serine cysteine transporter 2 inhibitor-based positron emission tomography tracer
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Synthesis and structure activity relationships of cyanopyridone based anti-tuberculosis agents
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3'-Deoxyribofuranosyl 7-deazapurine nucleoside analogues : a new class of highly potent antitrypanosomal agents
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Deazapurine nucleoside analogues as potent anti-Trypanosoma cruzi agents
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- Journal Article
- A1
- open access
6-O-alkylated 7-deazainosine nucleoside analogues : discovery of potent and selective anti-sleeping sickness agents
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Report on a novel emerging class of highly potent benzimidazole NPS opioids : chemical and in vitro functional characterization of isotonitazene
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- Journal Article
- A1
- open access
Structural basis of NKT cell inhibition using the T-cell receptor-blocking anti-CD1d antibody 1B1
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- Journal Article
- A1
- open access
A molecular switch in mouse CD1d modulates natural killer T cell activation by α-galactosylsphingamides
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Design and synthesis of trypanocidal purine nucleoside analogues : discovery of lead compounds for the treatment of sleeping sickness
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- Journal Article
- A1
- open access
Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness
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Purine nucleoside analogs as highly potent leads for the treatment of human African trypanosomiasis
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Novel pyrazolo[3,4-d]pyrimidine nucleosides : promising hits for Chagas disease and Leishmaniasis
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Synthesis and evaluation of 3’-deoxy-3’-fluoro-7-deazapurine nucleosides as antikinetoplastid agents
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- Conference Paper
- C3
- open access
Synthesis and biological evaluation of 1’-N-homoazanucleosides : discovery of a 5’-methylthioadenosine analogue with antitrypanosomal activity
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Purine nucleoside analogs as highly potent leads for the treatment of human African trypanosomiasis
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Discovery of 7-aryl-7-deazapurine 3'-deoxyribofuranosyl nucleoside analogues as anti-Trypanosoma cruzi agents
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Discovery of pyrrolo[2,3-b]pyridine (1,7-dideazapurine) nucleoside analogues as anti-Trypanosoma cruzi agents
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3’-Deoxy-3’-fluoro-7-deazapurine nucleosides : synthesis and evaluation against kinetoplastid parasites
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Discovery of pyrrolo[2,3-b]pyridine nucleoside analogues as anti-Trypanosoma cruzi agents
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- Journal Article
- A1
- open access
Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics
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Double prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents
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Phosphonodiamidate prodrugs of N-alkoxy analogs of a fosmidomycin surrogate as antimalarial and antitubercular agents
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Amino acid based prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents
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Ceramide-templated macrolactams : total synthesis and biological evaluation of macrocyclic α-galactosylceramide analogues and their aglycons
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- Journal Article
- A1
- open access
Broadening the message : a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells
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- Journal Article
- A1
- open access
New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma
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- Journal Article
- A1
- open access
RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients
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4''-O-Alkylated α-galactosylceramide analogues as iNKT-cell antigens : synthetic, biological, and structural studies
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Zwitterionic-hydrophilic interaction liquid chromatography for L-ascorbic acid 2-phosphate magnesium, a raw material in cell therapy
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Revisiting tubercidin against kinetoplastid parasites : aromatic substitutions at position 7 improve activity and reduce toxicity
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Optimized messenger RNA immunolipoplexes for cancer immunotherapy : balancing immunogenicity and adjuvancy
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C7 substituted 7-deaza adenosines : design and synthesis of nucleosides with potent antitrypanosomal activity
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- Journal Article
- A1
- open access
Regioselective ring opening of 1,3-dioxane-type acetals in carbohydrates
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Acyloxybenzyl and alkoxyalkyl prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents
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Synthesis toward bivalent ligands for the dopamine D2 and metabotropic glutamate 5 receptors
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- Journal Article
- A1
- open access
Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in Staphylococcus aureus
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Discovery of novel 7-aryl 7-deazapurine 3'-deoxy-ribofuranosyl nucleosides with potent activity against Trypanosoma cruzi
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- Journal Article
- A1
- open access
Synthesis of a 3'-C-ethynyl-β-D-ribofuranose purine nucleoside library : discovery of C7-deazapurine analogs as potent antiproliferative nucleosides
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- Conference Paper
- C3
- open access
4"-O-alkylated α-galactosylceramide analogues as iNKT cell antigens : synthetic, biological and structural studies
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- Journal Article
- A1
- open access
Identification and characterization of 4-chloromethamphetamine (4-CMA) in seized ecstacy : a risk to public health
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- Conference Paper
- C3
- open access
Synthesis of pyrrolidine-based hamamelitannin analogues in the search for potentiators for antibiotics against Staphylococcus aureus
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Tailored design of sugar-modified a-GalCer analogues for Th1-polarized immune responses
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Design, synthesis, and biological evaluation of bivalent ligands targeting dopamine D2-like receptors and the μ-opioid receptor
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Structure guided lead generation toward nonchiral M. tuberculosis thymidylate kinase inhibitors
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Novel 3'-deoxy purine nucleoside analogs as highly potent leads for human African trypanosomiasis
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Leptin receptor antagonism of iNKT cell function : a novel strategy to combat multiple myeloma
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- Journal Article
- A1
- open access
Identification of a new tert -leucinate class synthetic cannabinoid in powder and 'spice-like' herbal incenses : methyl 2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethyl-butanoate (5F-MDMB-PICA)
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Micellar paclitaxel-initiated RAFT polymer conjugates with acid-sensitive behavior
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Small-molecule potentiators for conventional antibiotics against Staphylococcus aureus
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Autoreactivity to sulfatide by human invariant NKT cells
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Synthesis of C6′′-modified α-C-GalCer analogues as mouse and human iNKT cell agonists
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- Journal Article
- A1
- open access
Efficient diastereoselective synthesis of a new class of azanucleosides : 2'-homoazanucleosides
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- Journal Article
- A1
- open access
Galactosylsphingamides : new α-GalCer analogues to probe the F’-pocket of CD1d
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- Journal Article
- A1
- open access
Novel hamamelitannin analogues for the treatment of biofilm related MRSA infections : a scaffold hopping approach
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Novel potentiators for vancomycin in the treatment of biofilm-related MRSA infections via a mix and match approach
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- Journal Article
- A1
- open access
Efficient divergent synthesis of new immunostimulant 4″-modified α-galactosylceramide analogues
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- Conference Paper
- C3
- open access
Hamamelitannin analogues potentiate antibiotics in the fight against biofilm-related Staphylococcus aureus infections
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Chemical dimerizers in three-hybrid systems for small molecule-target protein profiling
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- Journal Article
- A1
- open access
Targeting an aromatic hotspot in Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate reductoisomerase with β-arylpropyl analogues of fosmidomycin