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- Journal Article
- A1
- open access
A role for B cells to transmit hepatitis C virus infection
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Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1
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A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo
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- Conference Paper
- C3
- open access
Development and characterization of a human monoclonal antibody for prevention of HCV recurrence in liver transplant patients
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- Journal Article
- A1
- open access
Heads or tails : genotyping of hepatitis C virus concerning the 2k/1b circulating recombinant form
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Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge
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A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver
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A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver
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A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver
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Polyfunctional CD4⁺ T cell responses in HIV-1 infected viral controllers compared with those in healthy recipients of an adjuvanted polyprotein HIV-1 vaccine
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- Journal Article
- A1
- open access
Validation of an enzyme-linked immunosorbent assay for the quantification of human IgG directed against the repeat region of the circumsporozoite protein of the parasite Plasmodium falciparum.
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A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo
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In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus
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Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice
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HCV genotype distribution in Flanders and Brussels (Belgium): unravelling the spread of an uncommon HCV genotype 5a cluster
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- Journal Article
- A1
- open access
Baseline anti-NS4a antibodies in combination with on-treatment quantitative HCV-RNA reliably identifies nonresponders to pegylated interferon-ribavirin combination therapy after 4 weeks of treatment
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Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies
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ANTI-CD81 ANTIBODIES CAN PREVENT A HEPATITIS C VIRUS INFECTION IN VIVO
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Anti-CD81 Antibodies Can Prevent a Hepatitis C Virus Infection In Vivo
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Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain
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Serum levels of anti-NS4a and anti-NS5a predict treatment response of patients with chronic hepatitis C
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Partial delipidation improves the T-cell antigenicity of hepatitis B virus surface antigen
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Immunogenicity and tolerability of intradermal administration of an HCV E1-based vaccine candidate in healthy volunteers and patients with resolved or ongoing chronic HCV infection
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The duration of in vitro stimulation with recall antigens determines the subset distribution of interferon-gamma-producing lymphoid cells: A kinetic analysis using the Interferon-gamma Secretion Assay (TM)
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Comparison of qualitative (COBAS AMPLICOR HCV 2.0 versus VERSANT HCV RNA) and quantitative (COBAS AMPLICOR HCV monitor 2.0 versus VERSANT HCV RNA 3.0) assays for hepatitis c virus (HCV) RNA detection and quantification: impact on diagnosis and treatment of HCV infections
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Non-responsiveness to hepatitis B surface antigen vaccines is not caused by defective antigen presentation or a lack of B7 co-stimulation
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Comparison of two qualitative and two quantitative assays for HCV RNA detection and quantification: impact on diagnosis and treatment of HCV infections
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The interferon gamma secretion assay: a reliable tool to study interferon gamma production at the single cell level
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Evidence for a relation between the viral load and genotype and hepatitis C virus-specific T cell responses
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A candidate vaccine based on the hepatitis C E1 protein: tolerability and immunogenicity in healthy volunteers
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Humoral and cellular immune responses to subepidermal E1-based therapeutic vaccination in healthy volunteers and patients with past or ongoing HCV infections
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Characterization of HLA DR13-restricted CD4(+) T cell epitopes of hepatitis B core antigen associated with self-limited, acute hepatitis B.
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Immune response of HLA DQ2 positive subjects, vaccinated with HBsAg/ASO4, a hepatitis B vaccine with a novel adjuvant.
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Evolution of hepatitis C virus-specific T cell responses and cytokine production in chronic hepatitis C patients treated with high doses of interferon-alpha.
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The immunogenicity and reactogenicity profile of a candidate hepatitis B vaccine in an adult vaccine non-responder population.
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Prevention of hepatitis B infections: Vaccination and its limitations
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A candidate therapeutic vaccine for chronic hepatitis C infection based on envelope 1 protein: Tolerability and immunogenicity in healthy adult volunteers
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In vivo inhibition of anti-HBcIgG production by HBcAg-specific CD4+Th1-type T cell clones in a hu-PBL-NOD/SCID mice model
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Long-term persistence of antibodies induced by vaccination and safety follow-up, with the first combined vaccine against hepatitis A and B in children and adults
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Hepatitis B virus core antigen binds and activates naive human B cells in vivo: Studies with a human PBL-NOD/SCID mouse model.
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In vivo inhibition of anti-hepatitis B virus core antigen (HBcAg) immunoglobulin G production by HBcAg-specific CD4(+) Th1-type T-cell clones in a hu-PBL-NOD/SCID mouse model.
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Characterization of the T cell recognition of hepatitis B surface antigen (HBsAg) by good and poor responders to hepatitis B vaccines
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A hepatitis B vaccine formulated with a novel adjuvant system.
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- PhD Thesis
- open access
Human immune response to envelope proteins of the hepatitis B virus.
(1998) -
Response to hepatitis B vaccine: multiple HLA genes are involved
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Partial delipidation improves the T cell immunogenicity of hepatitis B surface antigen
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Response to hepatitis B vaccine: Multiple HLA genes are involved
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Safety and immunogenicity of a hepatitis B vaccine formulated with a novel adjuvant system.
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Cytotoxic T lymphocytes in HBV and HCV infections: beneficial or harmful ?
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Hepatitis B vaccine containing surface antigen and selected preS1 and preS2 sequences .1. Safety and immunogenicity in young, healthy adults.