prof. dr. Hans Nauwynck
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The role of accessory proteins in the replication of feline infectious peritonitis virus in peripheral blood monocytes
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Suppression of NK cell-mediated cytotoxicity against PRRSV-infected porcine alveolar macrophages in vitro
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- Journal Article
- A1
- open access
Development and use of a polarized equine upper respiratory tract mucosal explant system to study the early phase of pathogenesis of a European strain of equine arteritis virus
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Suppression of NK cells and regulatory T lymphocytes in cats naturally infected with feline infectious peritonitis virus
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Purification of white spot syndrome virus by iodixanol density gradient centrifugation
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- Journal Article
- A1
- open access
Development of a recombinant antibody to target peptides and proteins to sialoadhesin-expressing macrophages
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Antibody response and maternal immunity upon boosting PRRSV-immune sows with experimental farm-specific and commercial PRRSV vaccines
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Evaluation of viral peptide targeting to porcine sialoadhesin using a porcine reproductive and respiratory syndrome virus vaccination-challenge model
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Use of Staby® technology for development and production of DNA vaccines free of antibiotic resistance gene
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Separation of Penaeus vannamei haemocyte subpopulations by iodixanol density gradient centrifugation
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Porcine reproductive and respiratory syndrome virus infection is associated with an increased number of Sn-positive and CD8-positive cells in the maternal-fetal interface
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- Journal Article
- A1
- open access
Generation and characterization of feline arterial and venous endothelial cell lines for the study of the vascular endothelium
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- Journal Article
- A1
- open access
Establishment of feline intestinal epithelial cell cultures for the propagation and study of feline enteric coronaviruses
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Altered expression of adhesion molecules on peripheral blood leukocytes in feline infectious peritonitis
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Diagnosis of porcine rotavirus infections by RT-qPCR and RT-PCR reveals a possible synergism between enteric bacteria and genetically heterogeneous porcine rotaviruses in Belgium
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Complete genome analysis of Belgian porcine rotaviruses reveals a rather conserved porcine-like genotype constellation, despite large genetic diversity of VP7 and VP4
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Use of a new RT-qPCR assay for diagnosis of genetically heterogeneous porcine group A rotaviruses in Belgium reveals a possible synergism with enteric bacteria
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Establishment of feline intestinal epithelial cell cultures for the propagation and study of feline enteric coronaviruses
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ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-α-induced antiviral response
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Feline peripheral blood mononuclear cell cultivation: cell population evolution, FIV receptor expression, and FIV replication
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Contrasting replication of feline enteric coronavirus and feline infectious peritonitis virus in newly established feline intestinal epithelial cell cultures
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Effect of saliva stabilisers on detection of porcine reproductive and respiratory syndrome virus in oral fluid by quantitative reverse transcriptase real-time PCR
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Porcine, murine and human sialoadhesin (Sn/Siglec-1/CD169): portals for porcine reproductive and respiratory syndrome virus entry into target cells
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Identification of target cells of a European equine arteritis virus strain in experimentally infected ponies
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- Journal Article
- A1
- open access
Replication characteristics of porcine reproductive and respiratory syndrome virus (PRRSV) European subtype 1 (Lelystad) and subtype 3 (Lena) strains in nasal mucosa and cells of the monocytic lineage: indications for the use of new receptors of PRRSV (Lena)
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- Journal Article
- A1
- open access
Pathogenesis and prevention of placental and transplacental porcine reproductive and respiratory syndrome virus infection
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Development of two reproducible haemocyte culture systems for application in crustacean immunity studies
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The pathogenesis of porcine reproductive and respiratory syndrome (PRRS) is fully determined by the intriguing interplay of PRRSV with monocytic cells
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Complete genome characterization of a East European Type 1 subtype 3 porcine reproductive and respiratory syndrome virus
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Moult cycle of laboratory-raised Penaeus (Litopenaeus) vannamei and P. monodon
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Instability in vitro of a PCV2 infectious clone containing an insertion between ORF1 and ORF2
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In vitro assessment of the feline cell-mediated immune response against feline panleukopeniavirus, calicivirus and felid herpesvirus 1 using 5-bromo-2'-deoxyuridine labeling
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Diverse microbial interactions with the basement membrane barrier
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Cell tropism and entry of porcine circovirus 2
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Evaluation of the antiviral activity of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl]guanine (A-5021) against equine herpesvirus type 1 in cell monolayers and equine nasal mucosal explants
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The role of regulatory T cells during infection with feline infectious peritonitis virus
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The role of accessory proteins in the replication of feline infectious peritonitis virus in peripheral blood monocytes
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Contrasting replication kinetics of feline enteric coronavirus and feline infectious peritonitis virus in newly established feline intestinal epithelial cell cultures
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Antigenic subtyping and epitopes' competition analysis of porcine circovirus type 2 using monoclonal antibodies
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- Journal Article
- A1
- open access
Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis
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Single amino acid mutations in the capsid switch the neutralization phenotype of porcine circovirus 2
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Natural killer cells: frequency, phenotype and function in healthy cats
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- Journal Article
- A1
- open access
Immobilization of pseudorabies virus in porcine tracheal respiratory mucus revealed by single particle tracking
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Quantitative analysis of an anti-viral immune escape compound ML-7 in feline plasma using ultra performance liquid chromatography/electrospray ionization mass spectrometry
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- Journal Article
- A1
- open access
Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue
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- Journal Article
- A1
- open access
Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges
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Porcine sialoadhesin: a newly identified xenogeneic innate immune receptor
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Development of two haemocyte culture systems (in attachment and in suspension) for shrimp immunity studies
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Inhibitors of zinc-dependent metalloproteases hinder sperm passage through the cumulus oophorus during porcine fertilization in vitro
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- Journal Article
- A1
- open access
Susceptibility of juvenile Macrobrachium rosenbergii to different doses of high and low virulence strains of white spot syndrome virus (WSSV)
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Impact of a novel inactivated PRRS virus vaccine on virus replication and virus-induced pathology in fetal implantation sites and fetuses upon challenge
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Third international Havemeyer workshop on equine herpesvirus type 1 (EHV-1)
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Expression of late viral proteins is restricted in nasal mucosal leucocytes but not in epithelial cells during early-stage equine herpes virus-1 infection
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The pig: a model for human infectious diseases
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Clinical and virological outcome of an infection with the Belgian equine arteritis virus strain 08P178
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Micro-dissecting the pathogenesis and immune response of PRRSV infection paves the way for more efficient PRRSV vaccines
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- Journal Article
- A1
- open access
Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection
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Inactivated virus vaccines from chemistry to prophylaxis: merits, risks and challenges
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Kinetics of BoHV-1 dissemination in an in vitro culture of bovine upper respiratory tract mucosa explants
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Demonstration of microchimerism in pregnant sows and fetuses and putative microchimerism involvement in the pathogenesis of congenital PRRSV infection
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The role of vaccines for PRRS control and PRRSV eradication
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- Journal Article
- A1
- open access
Schmallenberg virus: emergence of an Orthobunyavirus among ruminants in Western Europe
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Porcine reproductive and respiratory syndrome virus (PRRSV) entry in its host cell, the macrophage
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Intriguing interplay between feline infectious peronitis virus and its receptors during entry in primary feline monocytes
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Quantification of regulatory T cells during infection with feline infectious peronitis virus
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Identification of non-neutralizing and neutralizing antigenic regions in PRRSV by the use of peptide-specific serum and antibodies
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Clinical pathological and virological outcome of an infection with the Belgian equine arteritis virus strain 08P178
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Herpes: the difficult one
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Better molecular insights in the pathogenesis of PRRSV infections and immune response show the way for more efficient PRRSV vaccines
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Outcome of porcine circovirus type 1 (PCV1) infections in mid-gestational porcine foetuses
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PRRSV challenge of late term pregnant gilts vaccinated with an experimental inactivated vaccine
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Increased replication of porcine circovirus type 2 in porcine cell cultures by statins
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- Conference Paper
- C3
- open access
Antigenic differences among PCV2 strains of different genetic clusters as demonstrated by the use of monoclonal antibodies generated against PCV2A or PCV2B
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Mapping of neutralizing epitopes in the capsid protein of porcine circovirus 2
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PRRSV efficiently replicates in fetal implantation sites and causes apoptosis in infected macrophages and surrounding cells
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- Conference Paper
- C3
- open access
Use of a farm-specific inactivated vaccine for boosting the humoral immunity of infection-immune sows in comparison with the current available commercial vaccines
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Efficacy of a farm-specific inactivated PRRSV vaccine in the field
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Comparison of the efficacy of inactivated PRRSV vaccine virus grown on MARC-145 or PK15SN-CD163 cells
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Research-driven development of new generation adaptable PRRSV vaccines
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Ultrasound prediction of the partus datum in dogs
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PRRSV binding to and/or internalization by its receptor sialoadhesin on macrophages is sufficient to compromise phagocytosis
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Exceptional outcome of an infection with a PCV2B strain in mid-gestational porcine foetuses
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Disordini riproduttivi di origine virale nella scrofa
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Expression of late viral proteins is hampered in infected nasal mucosal leukocytes but not in epithelial cells during early EHV-1 infection
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Equine herpesvirus 1 and 4 differ in their efficiency to infect mononuclear cells during early steps of infection in nasal mucosal explants
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Herpes Simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa
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Antibody binding to porcine sialoadhesin reduces phagocytic capacity without affecting other macrophage effector functions
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Intriguing interplay between feline infectious peritonitis virus and its receptors during entry in primary feline monocytes
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Porcine reproductive and respiratory syndrome virus (PRRSV) causes apoptosis during its replication in fetal implantation sites
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Equine alphaherpesviruses (EHV-1 and EHV-4) differ in their efficiency to infect mononuclear cells during early steps of infection in nasal mucosal explants
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- Journal Article
- A1
- open access
Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa
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- Journal Article
- A1
- open access
A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa
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Characterization of antigenic regions in the porcine reproductive and respiratory syndrome virus by the use of peptide-specific serum antibodies
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- Journal Article
- A1
- open access
Characterization of a circulating PRRSV strain by means of random PCR cloning and full genome sequencing
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- Journal Article
- A1
- open access
Outcome of experimental porcine circovirus type 1 infections in mid-gestational porcine foetuses
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Aujeszky's disease (pseudorabies): an old threat in current pig industry?, part I : pathogenetic information and implications
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Aujeszky's disease (pseudorabies): an old threat in current pig industry?, part II : epidemiology, immunity, prevention and the current situation in Greece
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- Journal Article
- A1
- open access
Comparative analysis of replication characteristics of BoHV-1 subtypes in bovine respiratory and genital mucosa explants: a phylogenetic enlightenment
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- Journal Article
- A1
- open access
Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages
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Role of group A p21-activated kinases in the anti-apoptotic activity of the pseudorabies virus US3 protein kinase