ereprof. dr. Joël Vandekerckhove
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Cathepsin B-mediated activation of the proinflammatory caspase-11
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Epithelial and fibroblastoid cells contain numerous cell-type specific putative microtubule-regulating proteins, among which are ezrin and fodrin
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Murine adseverin (D5), a novel member of the gelsolin family, and murine adseverin are induced by interleukin-9 in T-helper lymphocytes
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Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin.
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Disruption of the actin cytoskeleton of mammalian cells by the capping complex actin-fragmin is inhibited by actin phosphorylation and regulated by Ca2+ ions.
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Contribution of the hydrophobicity gradient of an amphipathic peptide to its mode of association with lipids.
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Analysis of three human interleukin 5 structures suggests a possible receptor binding mechanism.
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Enhanced efficiency of a targeted fusogenic peptide.
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Gelsolin and functionally similar actin-binding proteins are regulated by lysophosphatidic acid.
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Displacement of apo A-I from HDL by apo A-II or its C-terminal helix promotes the formation of pre-beta(1) migrating particles and decreases LCAT activation.
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A proposed architecture for lecithin cholesterol acyl transferase (LCAT): Identification of the catalytic triad and molecular modeling.
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Proteolytic mapping of kinesin/ncd-microtubule interface: nucleotide-dependent conformational changes in the loops L8 and L12.
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The presequence of yeast pAPl folds into different helical conformations to mediate targeting and translocation of the protein through the vacuolar membrane
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An abscisic-acid- and salt-stress-responsive rice cDNA from a novel plant gene family
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Aspartic proteinase genes in the Brassicaceae Arabidopsis thaliana and Brassica napus
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Identification and characterization of the 2-enoyl-CoA hydratases involved in peroxisomal beta-oxidation in rat liver.
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An effective potential for calculating free energies .1. General concepts and approximations.
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The photoactivatable inhibitor 7-azido-8-idoketanserin labels the N terminus of the vesicular monoamine transporter from bovine chromaffin granules.
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Identification of two regions in the N-terminal domain of ActA involved in the actin comet tail formation by Listeria monocytogenes.
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Apolipoprotein E inhibits liposome fusion induced by the Alzheimer's beta-amyloid peptide.
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Specific modulation of the fusogenic properties of the Alzheimer beta-amyloid peptide by apolipoprotein E isoforms.
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Structural and functional properties of the 154-171 wild-type and variant peptides of human lecithin-cholesterol acyltransferase.
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The mammalian profilin isoforms display complementary affinities for PIP2 and proline-rich sequences.
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Molecular cloning, over-expression, developmental regulation and immunolocalization of fragminP, a gelsolin-related actin-binding protein from Physarum polycephalum plasmodia.
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Novel techniques for identification and characterization of proteins loaded on gels in femtomole amounts.
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GRASP65, a protein involved in the stacking of Golgi cisternae.
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Ca2+-dependent interaction of S100A2 with muscle and nonmuscle tropomyosins.
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Peptides in membranes: Tipping the balance of membrane stability.
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Molecular analysis of the Rhodobacter capsulatus chaperone dnaKJ operon: Purification and characterization of DnaK.
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A phage display technique for a fast, sensitive, and systematic investigation of protein-protein interactions.
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Folding of the presequence of yeast pAPI into an amphipathic helix determines transport of the protein from the cytosol to the vacuole.
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Phosphatidylinositol 4,5-bisphosphate specifically stimulates PP60(c-src) catalyzed phosphorylation of gelsolin and related actin-binding proteins.
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Analogous F-actin binding by cofilin and gelsolin segment 2 substantiates their structural relationship
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The 118-135 peptide lot the human prion protein forms amyloid fibrils and induces liposome fusion.
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Peptides adsorbed on reverse-phase chromatographic beads as targets for femtomole sequencing by post-source decay matrix assisted laser desorption ionization-reflectron time of flight mass spectrometry (MALDI-RETOF-MS).
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Mammalian peroxisomal acyl-CoA oxidases. III. Molecular cloning and further characterization of human branched chain acyl-CoA oxidase
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Cloning of two proteins representing different subfamilies of a novel type / transmembrane protein family involved in vesicular trafficking
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Identification by sequence analysis of some critical (30kDa) proteins in aged beef
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Cofactor A is a molecular chaperone required for β-tubulin folding : functional and structural characterization
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T beta(4) is not a simple G-actin sequestering protein and interacts with F-actin at high concentration
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Evidence for an actin binding helix in gelsolin segment 2; Have homologous sequences in segments 1 and 2 of gelsolin evolved to divergent actin binding functions?
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The actin binding site of thymosin beta 4 mapped by mutational analysis
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A novel type of protein kinase phosphorylates actin in the actin-fragmin complex.
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In vivo phosphorylation of actin in Physarum polycephalum - Study of the substrate specificity of the actin-fragmin kinase.
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Further characterization of the peroxisomal 3-hydroxyacyl-CoA dehydrogenases from rat liver - Relationship between the different dehydrogenases and evidence that fatty acids and the C-27 bile acids di- and tri-hydroxycoprostanic acids are metabolized by separate multifunctional proteins.
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Fragmin, a microfilament regulatory protein from Physarum polycephalum, is phosphorylated by casein kinase II-type enzymes.
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Purification and characterization of chaperonin 60 and heat-shock protein 70 from chromoplasts of Narcissus pseudonarcissus - Involvement of heat-shock protein 70 in a soluble protein complex containing phytoene desaturase.
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Identification of two Physarum casein kinase II enzymes that phosphorylate fragmin, an endogenous actin-binding protein.
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Molecular analysis of the Rhodobacter capsulatus chaperonin (groESL) operon: Purification and characterization of Cpn60.
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The primary structure of a chondrichthyan protamine: A new apparent contradiction in protamine evolution.
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Single-step purification of two functional human apolipoprotein E variants hyperexpressed in Escherichia coli.
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A two plasmid co-expression system in Escherichia coli for the production of virion-like reverse transcriptase of the human immunodeficiency virus type 1.
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Analysis of the catalytic site of the actin ADP-ribosylating Clostridium perfringens iota toxin.
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Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome.
(1996) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 93(24). p.13748-13753 -
Human 2-D PAGE databases for proteome analysis in health and disease: http://biobase.dk/cgi-bin/celis.
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Structural analysis and identification of gel-purified proteins, available in the femtomole range, using a novel computer program for peptide sequence assignment, by matrix-assisted laser desorption ionization reflectron time-of-flight mass spectrometry.
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Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking.
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Detailed quantitative analysis of the actin-binding site of the actin-sequestering protein thymosin beta 4.
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Pathway leading to correctly folded beta-tubulin.
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Molecular cloning and expression of the Physarum actin-fragmin kinase (AFK) reveals a novel type of protein kinase.
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Differential binding of ligands to bovine profilin isoforms.
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Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide.
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Structural and functional characterization of Bovine profilin II
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Trypsin-mediated semisynthesis of salmon calcitonin
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Purification and characterization of bovine profilin II. Actin, poly (L-proline) and inositolphospholipid binding
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Microfilament Dynamics - Regulation of Actin Polymerization by Actin-Fragmin Kinase and Phosphatases.
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Conformational behaviour of a synthetic peptide of the C-terminus of villin that interacts with actin - an NMR, CD and simulated annealing study.
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Carotene desaturation is linked to a respiratory redox pathway in Varcissus pseudonarcissus-chromoplast membranes - Involvement of a 23-kDa oxygen-evolving-complex-like protein.
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PURIFICATION, IMMUNOLOGICAL CHARACTERIZATION AND CDNA CLONING OF A 47-KDA GLYCOPROTEIN SECRETED BY CARROT SUSPENSION CELLS.
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Localization of I-2-imidolazoline binding-sites on monoamine oxidases.
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An agarose-based gel-concentration system for microsequence and mass spectrometric characterization of proteins previously purified in polyacrylamide gels starting at low picomole levels.
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PURIFICATION AND CHARACTERIZATION OF BOVINE PROFILIN .2. ACTIN, POLY(L-PROLINE) AND INOSITOLPHOSPHOLIPID BINDING.
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STUDIES ON THE ACTIVE-SITE STRUCTURE OF C3-LIKE EXOENZYMES - INVOLVEMENT OF GLUTAMIC-ACID IN CATALYSIS OF ADP-RIBOSYLATION.
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THE SPECIFIC NH2-TERMINAL SEQUENCE AC-EEED OF ALPHA-SMOOTH MUSCLE ACTIN PLAYS A ROLE IN POLYMERIZATION IN-VITRO AND IN-VIVO.
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The human keratinocyte two-dimensional gel protein database (update 1995) : mapping components of signal transduction pathways
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SECRETION OF BIOLOGICALLY-ACTIVE MURINE INTERLEUKIN-2 BY LACTOCOCCUS-LACTIS SUBSP LACTIS.
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THE ACTIN-BINDING PROPERTIES OF THE PHYSARUM ACTIN-FRAGMIN COMPLEX - REGULATION OF CALCIUM, PHOSPHOLIPIDS, AND PHOSPHORYLATION.
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TRYPSIN-MEDIATED SEMISYNTHESIS OF SALMON-CALCITONIN.
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ADP-ribosyltransferase type-A from turkey erythrocytes modifies actin at Arg-95 and Arg-372.
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RHO-ADP-RIBOSYLATING EXOENZYME FROM BACILLUS-CEREUS - PURIFICATION, CHARACTERIZATION, AND IDENTIFICATION OF THE NAD-BINDING SITE.
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Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose
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Actin-actin binding protein interfaces
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Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-Jκ, by direct protein-protein interaction with Drosophila hairless
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A 92-kDa human immunostimulatory protein
(1994) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 91(18). p.8353-8357 -
β-actin specific monoclonal antibody
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Production of enzymatically active-rat protein disulfide-isomerase in Escherichia-coli.
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The residues Leu(Ile)475-Ile(Leu,Val, Ala)476, contained in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMPII to lysosomes.
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A novel cochaperonin that modulates the ATPases activity of cytoplasmic chaperonin.
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Molecular clotting, expression an characterization of PTPA, a protein that activates the tyrosyl phosphate activity of protein phosphatase 2A.
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CLONING, EXPRESSION, AND IN-SITU LOCALIZATION OF RAT INTESTINAL CGMP-DEPENDENT PROTEIN-KINASE-II.
(1994) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 91(20). p.9426-9430 -
THE ROOT EPIDERMIS-SPECIFIC PEA GENE RH2 IS HOMOLOGOUS TO A PATHOGENESIS-RELATED GENE.
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Purification of a cortical complex containing 2 unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose.
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The human keratinocyte two-dimensional protein database (update 1994) : towards an integrated approach to the study of cell proliferation, differentiation and skin-diseases
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A 50-KDA PROTEIN PRESENT IN CONDITIONED MEDIUM OF COLO-16 CELLS STIMULATES CELL SPREADING AND MOTILITY, AND ACTIVATES TYROSINE PHOSPHORYLATION OF NEU/HER-2, IN HUMAN SK-BR-3 MAMMARY-CANCER CELLS.
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Identification of two human rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton
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Eukaryotic cytosolic chaperonin contains t-complex polypeptide 1 and seven related subunits
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Human cellular protein patterns and their link to genome DNA mapping and sequencing data: towards an integrated approach to the study of gene expression
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Studies on the role of the processed regions of the Arabidopsis thaliana 2S albumin.
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Expression of modified seed storage proteins in transgenic plants
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Routine amino acid sequencing on 2D-gel separated proteins: a protein elution and concentration gel system