prof. dr. Luc Leybaert
work address
De Pintelaan 185, Blok B
9000 Gent
9000 Gent
ORCID iD
0000-0001-6452-6982
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- 2017
- Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+, and is modulated by CaMKII and p38MAPK
- Role of Cx43 hemichannels in ventricular arrhythmia associated with abnormal Ca2+ homeostasis
- Mitochondrial Cx43 hemichannels contribute to mitochondrial calcium entry and cell death in the heart
- Astrocytic gap junction blockade markedly increases extracellular potassium without causing seizures in the mouse neocortex
- The BH4 domain of Bcl-2 orthologues from different classes of vertebrates can act as an evolutionary conserved inhibitor of IP3 receptor channels
- Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+, and is modulated by CaMKII and p38MAPK
- Blocking connexin channels improves embryo development of vitrified bovine blastocysts
- 2016
- At the cross-point of connexins, calcium, and ATP: blocking hemichannels inhibits vasoconstriction of rat small mesenteric arteries
- IP3, still on the move but now in the slow lane
- Inhibition of Connexin43 hemichannels impairs spatial short-term memory without affecting spatial working memory