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The Pixel Variation Score: An Echocardiographic Index to Assess Temporal Variation of Mitral Regurgitant Flow
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Glucosuria and interference of urinary albumin-to-creatinine ratio
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- Journal Article
- A1
- open access
About the estimation of albuminuria based on proteinuria results
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- Journal Article
- A2
- open access
Clinical validation of a 13-lead electrocardiogram derived from a self-applicable 3-lead recording for diagnosis of myocardial supply ischaemia and common non-ischaemic electrocardiogram abnormalities at rest
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Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases
(2022) EUROPEAN JOURNAL OF HUMAN GENETICS. In European Journal of Human Genetics 30(Supplement 1). p.46-47 -
- Miscellaneous
- open access
Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases (vol 12, 6031, 2021)
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Athero : an observational cross-sectional evaluation of atherosclerotic risk control in the Belgian population treated with at least one antihypertensive and one lipid-lowering drug
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- Journal Article
- A1
- open access
COVID-19 related mortality and religious denomination vs. genetics
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Prognostic value of myocardial work and global longitudinal strain in patients with heart failure and functional mitral regurgitation
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Color Doppler splay in mitral regurgitation : hemodynamic correlates and outcome in a clinical cohort
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- Journal Article
- A1
- open access
ACE polymorphism is a determinant for COVID-19 mortality in the post-vaccination era
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- Journal Article
- A1
- open access
On the protein content of kidney stones : an explorative study
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Malignant cardiac tamponade : safety and efficacy of intrapericardial bleomycin instillation
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- Journal Article
- A1
- open access
Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases
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Sex differences in the association between arterial hypertension, blood pressure, and sleep apnea in the general population
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Genetic polymorphisms in the host and COVID-19 infection
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C-reactive protein in neonates and risk for autism spectrum disorder
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- Journal Article
- A1
- open access
Aortic valve implantation-induced conduction block as a framework towards a uniform electrocardiographic definition of left bundle branch block
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Iodine containing contrast media and urinary flow cytometry : an unknown interference in automated urine sediment analysis
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Longitudinal changes of input impedance, pulse wave velocity, and wave reflection in a middle-aged population : the Asklepios study
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- Journal Article
- A1
- open access
ABO blood groups and Coronavirus Disease 2019 (COVID-19)
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Vitamin D binding protein polymorphism and COVID-19
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The role of soluble receptor for advanced glycation end-products (sRAGE) in the general population and patients with diabetes mellitus with a focus on renal function and overall outcome
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A strain-based staging classification of left bundle branch block-induced cardiac remodeling
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The potential influence of human Y-chromosome haplogroup on COVID-19 prevalence and mortality
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Fibroblast growth factor 23 and the quest for the Holy Grail in heart failure : will the Crusaders be forced to surrender?
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The revised WHO list of essential diagnostics : still a matter of concern
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ACE polymorphism and COVID-19 outcome
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Proportionate or disproportionate secondary mitral regurgitation : how to untangle the Gordian knot?
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- Conference Paper
- C3
- open access
Ten years of ageing in the middle-aged does not increase input impedance or wave reflection : insights from the Asklepios study
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- Conference Paper
- C3
- open access
Effective impact of one decade of ageing on arterial system properties: what cross-sectional studies don't tell
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- Journal Article
- A1
- open access
L-index, more than a screening tool for hypertriglyceridemia
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On the use of lymphocyte to neutrophil ratios in laboratory medicine
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C3 and ACE1 polymorphisms are more important confounders in the spread and outcome of COVID-19 in comparison with ABO polymorphism
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ACE Ins/Del genetic polymorphism and epidemiological findings in COVID-19
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COVID-19 infections are also affected by human ACE1 D/I polymorphism
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The host's angiotensin-converting enzyme polymorphism may explain epidemiological findings in COVID-19 infections
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Septal flash is a prevalent and early dyssynchrony marker in transcatheter aortic valve replacement-induced left bundle branch block
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Average pixel intensity method for prediction of outcome in secondary mitral regurgitation
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- Journal Article
- A1
- open access
Carbamoylated nail proteins as assessed by near-infrared analysis are associated with load of uremic toxins and mortality in hemodialysis patients
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Urine test strips vs. pyrogallol red-molybdate assays for proteinuria : a critical approach
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Sex-specific sleep apnea screening questionnaires : closing the performance gap in women
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- Journal Article
- A1
- open access
Progression of incomplete toward complete left bundle branch block : a clinical and electrocardiographic analysis
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The average pixel intensity method and outcome of mitral regurgitation in mitral valve prolapse
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Muscle strength is a major determinant of the blood pressure response to isometric stress testing : the Asklepios population study
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Allometric versus ratiometric normalization of left ventricular stroke volume by Doppler-echocardiography for outcome prediction in severe aortic stenosis with preserved ejection fraction
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Feasibility and agreement of a novel combined echocardiographic method to measure global longitudinal strain and strain rate compared to speckle tracking and tissue Doppler imaging
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Insights into functional mitral regurgitation using the average pixel intensity method
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- Journal Article
- A1
- open access
Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population
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Phenotype and risk burden of sleep apnea : a population-based cohort study
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- Journal Article
- A1
- open access
Feasibility and performance of a device for automatic self-detection of symptomatic acute coronary artery occlusion in outpatients with coronary artery disease : a multicentre observational study
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Albumin assays and clinical decision-making in nephrotic syndrome patients
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Is creatine kinase an ideal biomarker in rhabdomyolysis? : reply to Lippi et al.: Diagnostic biomarkers of muscle injury and exertional rhabdomyolysis (https://doi.org/10.1515/cclm-2018-0656)
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Effect of obesity on left atrial strain in persons aged 35−55 years (The Asklepios Study)
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Grading of mitral regurgitation in mitral valve prolapse using the average pixel intensity method
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Prognostic value of masked uncontrolled hypertension : systematic review and meta-analysis
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Effect of obesity on left atrial strain in middle age : the Asklepios study
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- Journal Article
- A1
- open access
Reversal of aging-induced increases in aortic stiffness by targeting cytoskeletal protein-protein interfaces
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Progression of incomplete to complete left bundle branch block
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- Journal Article
- A1
- open access
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation
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Telomere length as cardiovascular aging biomarker
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Gender differences in electro-mechanical characteristics of left bundle branch block : potential implications for selection and response of cardiac resynchronization therapy
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- Journal Article
- A1
- open access
Interference of glucose and total protein on Jaffe-based creatinine methods : mind the covolume
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Twenty years of European IVD regulations and its aimed traceability : where are we?
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Iron status as a confounder in the gender gap in survival under extreme conditions
(2018) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 115(18). p.E4148-E4149 -
- Journal Article
- A1
- open access
Leukocyte telomere length and diet in the apparently healthy, middle-aged Asklepios population
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- Miscellaneous
- open access
Hypertension : time for doctors to switch the driver's seat?
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Relation between electrical and mechanical dyssynchrony in patients with left bundle branch block : an electro- and vectorcardiographic study
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Relation between electrical and mechanical dyssynchrony in patients with left bundle branch : an electrocardiographic and vectorcardiographic study
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From one-man bands to harmoniously playing chamber and full orchestras
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Carotid artery plaque and arterial stiffness : about conflicts between ultrasound and tonometry and between local and global
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Telomeres and atherosclerosis : the intricate pursuit of mechanistic insight through epidemiology
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Accuracy of computer-calculated and manual QRS duration assessments : clinical implications to select candidates for cardiac resynchronization therapy
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Improving cardiovascular risk prediction : a tale of Sisyphus
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Biventricular paced QRS area predicts acute hemodynamic CRT response better than QRS duration or QRS amplitudes
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Grading of mitral regurgitation based on intensity analysis of the continuous wave Doppler signal
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The relationship between the metabolic syndrome and arterial wall thickness : a mosaic still to be interpreted
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The evolutionary adaptation of hemochromatosis associated mutations during the neolithic
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Infrared spectroscopic imaging for interrogating the carbohydrate biochemistry of diabetic nephropathy progression
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A novel algorithm for quantification of mitral valve regurgitation based on pixel density analysis of continuous wave Doppler imaging
(2016) -
MRI assessment of diastolic and systolic intraventricular pressure gradients in heart failure
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The presence of fructosamine in human aortic valves is associated with valve stiffness
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Haptoglobin phenotype and Parkinson disease risk
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Diagnostic accuracy of a novel method for detection of acute transmural myocardial ischemia based upon a self-applicable 3-lead configuration
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- Journal Article
- A1
- open access
Assessment of model based (input) impedance, pulse wave velocity, and wave reflection in the Asklepios Cohort
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Ethnic-specific normative reference values for echocardiographic LA and LV size, LV mass, and systolic function : the EchoNoRMAL study
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The use of cardiovascular imaging in prognostic stratification
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- Journal Article
- A1
- open access
Decreasing initial telomere length in humans intergenerationally understates age-associated telomere shortening
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Associations between dietary inflammatory index and inflammatory markers in the Asklepios Study
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Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors
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- Journal Article
- A1
- open access
On cross-sectional associations of leukocyte telomere length with cardiac systolic, diastolic and vascular function: the Asklepios study
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Asymmetry in prevalence of femoral but not carotid atherosclerosis
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Effective arterial elastance is insensitive to pulsatile arterial load
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Detecting doping use: more than an analytical problem
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A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL study
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A non-genetic, epigenetic-like mechanism of telomere length inheritance?
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Longitudinal myocardial strain alteration is associated with left ventricular remodeling in asymptomatic patients with type 2 diabetes mellitus
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Arterial stiffness and influences of the metabolic syndrome: a cross-countries study
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Usefulness of indirect alcohol biomarkers for predicting recidivism of drunk-driving among previously convicted drunk-driving offenders: results from the Recidivism Of Alcohol-impaired Driving (ROAD) study
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- Journal Article
- A1
- open access
Triiodothyronine and free thyroxine levels are differentially associated with metabolic profile and adiposity-related cardiovascular risk markers in euthyroid middle-aged subjects
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Reperfusion therapy and mortality in octogenarian STEMI patients: results from the Belgian STEMI registry
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Children's sleep and the autonomic function: low sleep quality has an impact on heart rate variability independent of stress
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Arterial stiffness and subclinical inflammation in the general population: the Asklepios study
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Influence of physical properties of cuvette surface on measurement of serum lipase
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- Journal Article
- A1
- open access
Genetic aspects of scurvy and the European famine of 1845-1848
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- Journal Article
- A1
- open access
α₁-Microglobulin/albumin ratio may improve interpretation of albuminuria in statin-treated patients
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Agglutination of intravenously administered phosphatidylcholine-containing lipid emulsions with serum C-reactive protein
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Traitements axés sur les HDL: traitement d'un facteur de risque ou maquillage d'un marqueur de risque?
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HDL-gerichte therapieën: behandeling van een risicofactor of 'make-up' van een risicomerker?
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Effect of body side on atherosclerosic distribution in the carotid and femoral arteries
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PF-4var/CXCL4L1 predicts outcome in stable coronary artery disease patients with preserved left ventricular function
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Latent Transforming growth factor Binding Protein 2 (LTBP2) is related to phenotypic changes suggestive for HFPEF in stable outpatients with coronary artery disease and preserved ejection fraction
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Reference intervals for common carotid intima-media thickness measured with echotracking: relation with risk factors
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Central pulse pressure and its hemodynamic determinants in middle-aged adults with impaired fasting glucose and diabetes
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Immunonephelometric carbohydrate-deficient transferrin results and transferrin variants
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- Journal Article
- A1
- open access
Thyroid hormone levels within reference range are associated with heart rate, cardiac structure, and function in middle-aged men and women
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Associations between single nucleotide polymorphisms in thyroid hormone transporter genes (MCT8, MCT10 and OATP1C1) and circulating thyroid hormones
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Children's sleep and autonomic function: low sleep quality has an impact on heart rate variability
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Children’s heart rate variability as stress indicator : association with reported stress and cortisol
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Family history of cardiovascular disease and offspring echocardiographic left ventricular structure and function: the Asklepios study
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Microheterogeneity of serum β-hexosaminidase in chronic alcohol abusers in a driver's license regranting program
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2013 ESH/ESC Guidelines for the management of arterial hypertension
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The 2013 ESH/ESC guidelines for the management of arterial hypertension
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2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
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- Journal Article
- A1
- open access
Addition of a novel, protective family history category allows better profiling of cardiovascular risk and atherosclerotic burden in the general population: the Asklepios study
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Is myocardial revascularisation safe in trainees' hands?
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Relationship between effective arterial elastance and specific measures of arterial properties in middle age: the Asklepios study
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Central pulse pressure and its hemodynamic determinants in middle-aged adults with impaired fasting glucose and diabetes mellitus: the Asklepios study
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Interchangeability of venous and capillary HbA1c results is affected by oxidative stress
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Non-oxidative ethanol metabolites as a measure of alcohol intake
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Unanswered questions in including HDL-cholesterol in the cardiovascular risk estimation: is time still on our side?
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- Journal Article
- A1
- open access
Determinants and reference values of short-term heart rate variability in children
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Associations of rs4704397 in phosphodiesterase 8B with thyrotropin and thyroid hormone concentrations
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- Journal Article
- A1
- open access
Early and late systolic wall stress differentially relate to myocardial contraction and relaxation in middle-aged adults: the Asklepios study
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Stress biomarkers in children: heart rate variability versus salivary cortisol
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Noninvasive determination of local pulse wave velocity and wave intensity: changes with age and gender in the carotid and femoral arteries of healthy human
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High-sensitive C-reactive protein: universal prognostic and causative biomarker in heart disease?
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Carbohydrate deficient transferrin in a driver's license regranting program
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Human plasma protein polymorphisms and the persistence of cultural diversity
(2012) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 109(43). p.E2914-E2914 -
No shorter telomeres in subjects with a family history of cardiovascular disease in the Asklepios Study
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- Journal Article
- A1
- open access
PF-4var/CXCL4L1 predicts outcome in stable coronary artery disease patients with preserved left ventricular function
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HFpEF, diastolic suction, and exercise
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Arterial properties as determinants of time-varying myocardial stress in humans
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Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium
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The change in arterial stiffness over the cardiac cycle rather than diastolic stiffness is independently associated with left ventricular mass index in healthy middle-aged individuals
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Behavioural and psychosocial correlates of nondipping blood pressure pattern among middle-aged men and women at work
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STEMI and octogenarians: gender specific predictors of mortality and gender differences in reperfusion: results from the Belgian STEMI registry
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- Journal Article
- A1
- open access
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
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- Miscellaneous
- open access
How to treat arterial stiffness beyond blood pressure lowering?
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Vitamin C deficiency: more than just a nutritional disorder
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The change in pulse wave velocity over the cardiac cycle is independently associated with left ventricular mass index in middle-aged healthy subjects
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Modest opposite associations of endogenous testosterone and oestradiol with left ventricular remodelling and function in healthy middle-aged men
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Association of haptoglobin phenotypes with the development of Kaposi's sarcoma in HIV patients
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Haptoglobin polymorphism: a key factor in the proatherogenic role of B cells?
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Increased urinary neutrophil gelatinase associated lipocalin in urinary tract infections and leukocyturia
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Telomere length and cardiovascular aging: the means to the ends?
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Diastolic dysfunction in patients with type 2 diabetes mellitus: is it really the first marker of diabetic cardiomyopathy?
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Donor haptoglobin phenotype determines outcome following liver transplantation
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- Journal Article
- A1
- open access
Response to method errors or unexplained biological information?
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The relationship between diet and subclinical atherosclerosis : results from the Asklepios study
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STEMI and octogenarians: influence of age and gender on mortality and reperfusion: results from the Belgium STEMI registry
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- Conference Paper
- C3
- open access
The Arteriograph : measuring axillo-brachial rather than aortic stiffness?
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Impaired hemoglobin scavenging during an acute HIV-1 retroviral syndrome
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Difference between systolic and diastolic carotid artery stiffness is independently associated with left ventricular mass index in healthy middle-aged subjects
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Investigation of the potential association of vitamin D binding protein with lipoproteins
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- Conference Paper
- C3
- open access
Difference between systolic and diastolic carotid artery stiffness is independently associated with left ventricular mass index in healthy middle-aged subjects
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Noninvasive assessment of diastolic intraventricular pressure gradients in a large general population (the Asklepios study)
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Cardiovascular determinants and prognostic significance of CC Chemokine Ligand-18 (CCL18/PARC) in patients with stable coronary artery disease
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Impaired myocardial radial function in asymptomatic patients with type 2 diabetes mellitus: a speckle-tracking imaging study
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Donor haptoglobin phenotype determines iron status and outcome following liver transplantation
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Evaluation of standard and advanced preprocessing methods for the univariate analysis of blood serum 1H-NMR spectra
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- Journal Article
- A1
- open access
Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: 'establishing normal and reference values'
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The Arteriograph: correlated to aortic stiffness, but measuring axillo-brachial artery stiffness?
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Numerical validation of the working principle of the arteriograph
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- Journal Article
- A1
- open access
Silence of the limbs: pharmacological symptomatic treatment of intermittent claudication
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- Conference Paper
- C3
- open access
Correlates of nondipping blood pressure pattern among middle-aged men and women
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Stickler syndrome caused by COL2A1 mutations: genotype-phenotype correlation in a series of 100 patients
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Left ventricular mass: allometric scaling, normative values, effect of obesity, and prognostic performance
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- Journal Article
- A1
- open access
Numerical validation of a new method to assess aortic pulse wave velocity from a single recording of a brachial artery waveform with an occluding cuff
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Noninvasive assessment of central and peripheral arterial pressure (waveforms): implications of calibration methods
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Quantification of both systolic and diastolic arterial stiffness improves identification of arterial stiffening with normal aging
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Assessing arterial distensibility using ultrasound wall-tracking diameter distension: an urgent need for direct stiffness measurement!
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Blood pressure waveform analysis by means of wavelet transform
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Arterial load and ventricular-arterial coupling: physiologic relations with body size and effect of obesity
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Chromosome 9p21 Polymorphism Interacts With Waist-to-Hip Ratio in Carotid Plaque
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Decreased Radial Function is Associated With Subtle Left Ventricular Remodeling in Type 2 Diabetes Mellitus
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Limitations and pitfalls of non-invasive measurement of arterial pressure wave reflections and pulse wave velocity
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- Journal Article
- A1
- open access
Flawed Measurement of Brachial Tonometry for Calculating Aortic Pressure? Response
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Plasma vitamin C for predicting cardiovascular disease: more than a nutritional biomarker
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Selective genetic advantages for users of thiazide diuretics. Is there a case for the 460Trp variant of alpha-adducin?
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Prognostic value of the oxygen uptake efficiency slope in patients with coronary artery disease and intermediate peak VO2
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Clinical impact of adducin polymorphism Reply
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The reservoir pressure concept: the 3-element windkessel model revisited?: application to the Asklepios population study
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A population based approach for the conversion between PWV path length definitions
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Distance measurements for the assessment of carotid to femoral pulse wave velocity
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Prevalence of Chlamydophila psittaci infections in a human population in contact with domestic and companion birds
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The association between job strain and blood pressure variability in middle-aged men and women
(2009) International Journal of Occupational Medicine and Environmental Health. 22(Supplement). p.S44-S44 -
Amplification of the Pressure Pulse in the Upper Limb in Healthy, Middle-Aged Men and Women
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Relationship Between Ventricular Afterload and Early Diastolic Ventricular Relaxation: The Asklepios Study
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Comparison of three different methods to calculate aortic pulse wave velocity (PWV) using a 1D model of the systemic circulation
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Carbohydrate deficient transferrin and forensic medicine
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Systemic telomere length and preclinical atherosclerosis : the Asklepios study
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Arterial load and ventricular-arterial coupling: physiologic relations with body size and effect of obesity
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Time-varying myocardial stress and systolic pressure-stress relationship: role in myocardial-arterial coupling in hypertension
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Circulating oxidized low-density lipoprotein : a biomarker of atherosclerosis and cardiovascular risk?
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Night-day blood pressure ratio and dipping pattern as predictors of death and cardiovascular events in hypertension
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ESTIMATED CENTRAL BLOOD PRESSURE: IMPORTANCE OF RADIAL ARTERY PRESSURE WAVEFORM CALIBRATION
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Evaluation of Noninvasive Methods to Assess Wave Reflection and Pulse Transit Time From the Pressure Waveform Alone
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Using flow waveform approximations for aortic wave reflection and pulse transit time assessment: a critical evaluation
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Management of hypertension in peripheral arterial disease
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The reservoir pressure concept: the 3-element windkessel model revisited? Application to the Asklepios population study
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Reservoir pressure and the 3-element Windkessel model in the Asklepios population
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- Conference Paper
- C3
- open access
Estimated central blood pressure, importance of radial artery pressure waveform calibration
(2008) -
Wave reflections in the arterial tree: from clinical research to the hydraulic bench
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Long term oral contraceptive use is an independent risk factor for arterial stiffening
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Prognostic significance of ambulatory blood pressure in hypertensive patients with history of cardiovascular disease
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Long term oral contraceptive use is an independent risk factor for arterial stiffening
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An improved method for wave reflection assessment via flow wave approximation
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- Conference Paper
- C3
- open access
Evaluation of a method of deriving aortic pulse wave velocity from a single pulse recording
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Validation of the working principle of the Arteriograph, a new device to measure pulse wave velocity
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Numerical, experimental, and clinical assessment of wave reflections in the human arterial tree
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Femoral Plaques Confound the Association of Circulating Oxidized 951 Low-density Lipoprotein with Carotid Atherosclerosis in a General Population Aged 35-55 Years (Asklepios Study)
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Relation between arterial load and left ventricular relaxation in a large population sample of healthy, middle-aged subjects.
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Relation between left ventricular relaxation rate and arterial loading
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Impact of radial artery pressure waveform calibration on estimated central pressure using a transfer function approach
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Studying telomeres in a longitudinal population based study
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Determining carotid artery pressure from scaled diameter waveforms: comparison and validation of calibration techniques in 2026 subjects
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Lower red blood cell counts in middle-aged subjects with shorter peripheral blood leukocyte telomere length
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Poststress left ventricular ejection fraction is an independent predictor of major cardiac events in patients with coronary artery disease and impaired left ventricular function
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Unusual serum electrophoresis pattern in a woman with pancreatic carcinoma
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Three- and four-element Windkessel models: assessment of their fitting performance in a large cohort of healthy middle-aged individuals
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Variation in HDL cholesterol methodology and calibration may lead to erroneous cardiovascular risk estimation
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Carotid artery structure and large artery stiffness in 2524 middle-aged men and women (asklepios study): Integrating morphology and mechanics
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Age and gender related patterns in carotid-femoral PWV and carotid and femoral stiffness in a large healthy, middle-aged population
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Femoral plaques confound the association of circulating oxidized low-density lipoprotein with carotid atherosclerosis in a general population aged 35 to 55 years - The Asklepios study
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Oxidized low-density lipoprotein cholesterol is associated with decreases in cardiac function independent of vascular alterations
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NMR-based characterization of metabolic alterations in hypertension using an adaptive, intelligent binning algorithm
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Daytime and nighttime blood pressure as predictors of death and cause-specific cardiovascular events in hypertension
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How to treat hypertension in patients with peripheral artery disease
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Influence of sex on arterial stiffening evaluated using a pressure-dependent, geometry-independent stiffness index
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Influence of sex on arterial stiffening evaluated using a pressure-dependent, geometry-independent stiffness index
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Common carotid artery stiffness: more sensitive to age and gender related large artery stiffening than aortic pulse wave velocity?
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Evaluation of a method of wave reflection assessment via triangular flow wave approximation
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Anticonceptive drug use and increased carotid and femoral plaque prevalence: Population data from asklepios
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Oral contraceptives cause major C-reactive protein rises in the female general population
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A new non-invasive method for assessing the intrinsic active strength of human left ventricular tissue
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Wave reflection assessment via flow wave approximation: triangular versus population-based waveform
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Endothelial outgrowth cells are not derived from CD133(+) cells or CD45(+) hematopoietic precursors
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Effect of radial artery calibration method and transfer function on estimated central blood pressure
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Relation between arterial stiffness, wave reflection, aortic characteristic impedance and windikessel compliance in healthy middle-aged subjects and their contribution to carotid pulse pressure