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Aspergillus fumigatus recognition by dendritic cells negatively regulates allergic lung inflammation through a TLR2/MyD88 pathway
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Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties
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- Journal Article
- A1
- open access
Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes
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- Journal Article
- A1
- open access
Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12
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Arginine-rich peptide-based mRNA nanocomplexes efficiently instigate cytotoxic T cell immunity dependent on the amphipathic organization of the peptide
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Mycolates of Mycobacterium tuberculosis modulate the flow of cholesterol for bacillary proliferation in murine macrophages
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Type I interferons modulate CD8⁺ T cell immunity to mRNA vaccines
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- Journal Article
- A2
- open access
Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice
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pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation
(2016) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 113(29). p.8098-8103 -
- Journal Article
- A1
- open access
pH-Degradable mannosylated nanogels for dendritic cell targeting
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Coadministration of a plasmid encoding HIV-1 Gag enhances the efficacy of cancer DNA vaccines
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Mycobacterium tuberculosis-associated synthetic mycolates differentially exert immune stimulatory adjuvant activity
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Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses
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Spontaneous protein adsorption on graphene oxide nanosheets allowing efficient intracellular vaccine protein delivery
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- Journal Article
- A1
- open access
Vaccination with necroptotic cancer cells induces efficient anti-tumor immunity
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Engineering polymer hydrogel nanoparticles for lymph node-targeted delivery
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GM-CSF treatment prevents respiratory syncytial virus– induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation
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Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation
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- Journal Article
- A1
- open access
Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages
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- Journal Article
- A1
- open access
E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo
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The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation
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Nanoporous polyelectrolyte vaccine microcarriers: a formulation platform for enhancing humoral and cellular immune responses
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Nanoporous hydrogen bonded polymeric microparticles: facile and economic production of cross presentation promoting vaccine carriers
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- Journal Article
- A1
- open access
Boosting in planta production of antigens derived from the porcine reproductive and respiratory syndrome virus (PRRSV) and subsequent evaluation of their immunogenicity
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Challenges and advances towards the rational design of mRNA vaccines
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- Journal Article
- A1
- open access
M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A
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Lipoplexes carrying mRNA encoding Gag protein modulate dendritic cells to stimulate HIV-specific immune responses
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Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines
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Surface-engineered polyelectrolyte multilayer capsules: synthetic vaccines mimicking microbial structure and function
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Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection
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- Journal Article
- A1
- open access
Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family members
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Towards understanding the functional diversity of cell wall mycolic acids of Mycobacterium tuberculosis
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Spatiotemporal autophagic degradation of oxidatively damaged organelles after photodynamic stress is amplified by mitochondrial reactive oxygen species
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- Journal Article
- A1
- open access
IL-15 augments TCR-induced CD4⁺ T cell expansion in vitro by inhibiting the suppressive function of CD25High CD4⁺ T cells
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Innate imprinting of murine resident alveolar macrophages by allergic bronchial inflammation causes a switch from hypoinflammatory to hyperinflammatory reactivity
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Polyelectrolyte LbL microcapsules versus PLGA microparticles for immunization with a protein antigen
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Single-step formation of degradable intracellular biomolecule microreactors
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Lyophilization of protein-loaded polyelectrolyte microcapsules
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- Journal Article
- A1
- open access
Polymeric multilayer capsules delivering biotherapeutics
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- Journal Article
- A1
- open access
Do-it-yourself: construction of a custom cDNA macroarray platform with high sensitivity and linear range
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Inflammatory signatures for eosinophilic vs. neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints
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Designing polymeric particles for antigen delivery
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Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern
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Polymeric multilayer capsules in drug delivery
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Structure-function relationships of the antigenicity of mycolic acids in tuberculosis patients
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Facile two-step synthesis of porous antigen-loaded degradable polyelectrolyte microspheres
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PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1
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- Journal Article
- A1
- open access
Transcriptome analysis of monocyte-HIV interactions
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Polyelectrolyte capsules-containing HIV-1 p24 and poly I:C modulate dendritic cells to stimulate HIV-1-specific immune responses
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- Journal Article
- A1
- open access
A single step process for the synthesis of antigen laden thermosensitive microparticles
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Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery
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Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes
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Polyelectrolyte Microcapsules as Antigen Delivery Vehicles To Dendritic Cells: Uptake, Processing, and Cross-Presentation of Encapsulated Antigens
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Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris
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The first unique synthetic mycobacterial cord factors
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Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice
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New asthma biomarkers: lessons from murine models of acute and chronic asthma
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Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma
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Cholesteroid nature of free mycolic acids from M. tuberculosis
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Mycolic acids for the control of tuberculosis
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IL-15 augments CD4+T-cell proliferation by inhibiting the suppressive function of CD25HighCD4+regulatory T-cells
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Macrophage reprogramming by mycolic acid promotes a tolerogenic response in experimental asthma
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Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapy
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Blocking tumor cell eicosanoid synthesis by GPx4 impedes tumor growth and malignancy
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Animal models of allergen-induced tolerance in asthma: are T-regulatory-1 cells (Tr-1) the solution for T-helper-2 cells (Th-2) in asthma?
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Tumor cell eicosanoids promote tumor growth, metastasis and escape from angiodestructive tumor therapy
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Lysophosphatidic acid affinity chromatography reveals pyruvate kinase as a specific LPA-binding protein
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CD3 x CD28 cross-interacting bispecific antibodies improve tumor cell dependent T-cell activation
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Enhancement of polymethacrylate-mediated gene delivery by Penetratin
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IL-15 and IL-15R alpha in CD4(+) T cell immunity
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The Mycobacterium tuberculosis cell wall component mycolic acid elicits pathogen-associated host innate immune responses
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Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation
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Lipo-protein I, a TLR2/4 ligand modulates Th2-driven allergic immune responses
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Enhancement of polymethacrylate-mediated gene delivery by penetratin
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Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter
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Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders
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Cytoglobin expression is upregulated in all tissues upon hypoxia: an in vitro and in vivo study by quantitative real-time PCR
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New strategies in polypeptide and antibody synthesis: An overview
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Buffering properties of cationic polymethacrylates are not the only key to successful gene delivery
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Membrane interaction and cellular internalization of penetratin peptides
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Eicosanoid mediators in health, inflammation and cancer.
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Airway IgG counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on Fc gamma R and IFN-gamma
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Antigen presentation by local macrophages promotes nonallergic airway responses in sensitized mice
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Optimizing expression and purification from cell culture medium of trispecific recombinant antibody derivatives
(2003) JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 786(1-2). p.161-176 -
Regulation of T-cell life and death in the periphery.
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Induction of IL-15 by TCR/CD3 aggregation depends on IFN-gamma and protects against apoptosis of immature thymocytes in vivo.
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Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methyl glyoxal-derived AGE.
(2002) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 99(2). p.949-954 -
New recombinant bi- and trispecific antibody derivatives
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A new model for intermediate molecular weight recombinant bispecific and trispecific antibodies by efficient heterodimerization of single chain variable domains through fusion to a Fab-chain.
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Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.
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Role of reactive oxygen species in tumor necrosis factor toxicity
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Macrophages present pinocytosed exogenous antigen via MHC class I whereas antigen ingested by receptor-mediated endocytosis is presented via MHC class II.
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Interleukin-15 redirects the outcome of a tolerizing T-cell stimulus from apoptosis to anergy.
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Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential.
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- Journal Article
- A1
- open access
Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria.
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Efficient heterodimerization of recombinant bi- and trispecific antibodies.
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Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives.
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Tumor necrosis factor-induced microtubule stabilization mediated by hyperphosphorylated oncoprotein 18 promotes cell death.
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Regulation of tumor necrosis factor-induced, mitochondria- and reactive oxygen species-dependent cell death by the electron flux through the electron transport chain complex I
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Redox regulation of TNF signaling.