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- 0000-0002-3291-8065
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Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models
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Nieuwe inzichten betreffende metastasen
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Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo
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Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research
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Glucocorticoids indirectly decrease colon cancer cell proliferation and invasion via effects on cancer-associated fibroblasts
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Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF1R activation
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When neighbors talk : colon cancer cell invasion and tumor microenvironment myofibroblasts
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- Journal Article
- A1
- open access
Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth
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- Journal Article
- A1
- open access
ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer
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A JAK3/STAT3 passenger activation in a lapatinib-acquired resistance model of HER2-amplified breast cancer
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- Journal Article
- A1
- open access
Improved synthesis and comparative analysis of the tool properties of new and existing D-ring modified (S)-blebbistatin analogs
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- Journal Article
- A1
- open access
Insights into the myosin II inhibitory potency of A-ring-modified (S)-blebbistatin analogs
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- Journal Article
- A1
- open access
Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor
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- Journal Article
- A1
- open access
Discovery of (S)-3′-hydroxyblebbistatin and (S)-3′-aminoblebbistatin : polar myosin II inhibitors with superior research tool properties
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Discovery of anti-invasive tools and leads for the study and treatment of metastatic cancer : two case studies
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Discovery and development of new anti-invasive agents, an unmet clinical need
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- Conference Paper
- C3
- open access
NewTumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells
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- Conference Paper
- C3
- open access
The effects of quorum sensing peptides on colon cancer cells: implications for the role of the gut microbiome
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- Journal Article
- A1
- open access
Age and cellular context influence rectal prolapse formation in mice with caecal wall colorectal cancer xenografts
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- Journal Article
- A1
- open access
Genipin-crosslinked gelatin microspheres as a strategy to prevent postsurgical peritoneal adhesions : in vitro and in vivo characterization
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Quantitative evaluation of single cell spread on collagen matrices
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Radiation-induced collateral damage : impact on metastasis
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Discovery of novel nonmuscle myosin II inhibitors as chemical tools and antimetastatic therapeutics leads
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Discovery of novel nonmuscle myosin II inhibitors as antimetastatic therapeutics leads and chemical tools
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- Journal Article
- A2
- open access
Selective glucocorticoid receptor-activating adjuvant therapy in cancer treatments
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Dissemination and adhesion of peritoneal cancer cells to the peritoneal wall
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4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent: from discovery to initial validation in an in vivo metastasis model
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4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent : from discovery to initial validation in an in vivo metastasis model
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Pharmacological evaluation of the anti-invasive agent 4-fluoro-3',4',5'-trimethoxychalcone
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4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent: from discovery to initial validation in an in vivo metastasis model
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Quantitative and functional requirements for bioluminescent cancer models
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Chick heart invasion assay for testing the invasiveness of cancer cells and the activity of potentially anti-invasive compounds
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Glucocorticoids and the non-steroidal selective glucocorticoid receptor modulator, compound A, differentially affect colon cancer-derived myofibroblasts
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8-prenylnaringenin and tamoxifen inhibit the shedding of irradiated epithelial cells and increase the latency period of radiation-induced oral mucositis
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- Journal Article
- A1
- open access
Microbial inhibition of oral epithelial wound recovery: potential role for quorum sensing molecules?
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4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent: from discovery to initial validation in an in vivo metastasis model
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- Journal Article
- A2
- open access
Effects of irradiation on epithelial wound healing and microbial diversity in an in-vitro oral mucosa model
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Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents
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Anti-inflammatory and antioxidant properties of Piper species: a perspective from screening to molecular mechanisms
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The competence of 7,8-diacetoxy-4-methylcoumarin and other polyphenolic acetates in mitigating the oxidative stress and their role in angiogenesis
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- Journal Article
- A1
- open access
Radiation-induced lung damage promotes breast cancer lung-metastasis through CXCR4 signaling
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- Journal Article
- A1
- open access
Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade
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Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics
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- Journal Article
- A2
- open access
Data on in vivo selection of SK-OV-3 Luc ovarian cancer cells and intraperitoneal tumor formation with low inoculation numbers
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- Conference Paper
- C3
- open access
Communication of quorum sensing peptides with breast cancer cells
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Further studies on anti-invasive chemotypes: an excursion from chalcones to curcuminoids
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- Journal Article
- A1
- open access
The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro
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Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells
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Crosstalk between the microbiome and cancer cells by quorum sensing peptides
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Combination of dexamethasone with the selective glucocorticoid receptor modulator, Compound A, does not enhance glucocorticoid responsiveness in lymphoid malignancies
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Impact of neoadjuvant therapy on cancer-associated fibroblasts in rectal cancer
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- Journal Article
- A1
- open access
Cancer-associated fibroblasts connect metastasis-promoting communication in colorectal cancer
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The serum estradiol concentration is the main determinant of the estradiol concentration in normal breast tissue
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Combined inhibition of rho-associated protein kinase and EGFR suppresses the invasive phenotype in EGFR-dependent lung cancer cells
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Stromal protein expression in breast cancer is differentially regulated by TGF-β1
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- Journal Article
- A2
- open access
Dynamic shifts in the oral microbiome during radiotherapy
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Single cell and spheroid collagen type I invasion assay
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- Journal Article
- A1
- open access
Pharmacological levels of withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells
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Development of an oral mucosa model to study host-microbiome interactions during wound healing
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- Journal Article
- A1
- open access
Sub-emetic toxicity of Bacillus cereus toxin cereulide on cultured human enterocyte-like Caco-2 cells
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Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling
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DFT/B3LYP calculated bond-dissociation enthalpies, radical-scavenging and antioxidant activities of natural-like coumarins
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Carcinoma-associated fibroblasts provide operational flexibility in metastasis
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Modifications of cell signalling and redox balance by targeting protein acetylation using natural and engineered molecules: implications in cancer therapy
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On the quest for new anti-invasive agents: from the discovery of 4-fluoro-3',4','5'-trimethoxychalcone to its initial validation in an in vivo metastasis model
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- Conference Paper
- C3
- open access
How does the human microbiome affect cancer outcome?
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- Conference Paper
- C3
- open access
Quorum sensing peptides: missing link between microbiome and health?
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An immunogen synthesis strategy for the development of specific anti-deoxynivalenol monoclonal antibodies
(2014) FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT. 31(10). p.1751-1759 -
- Conference Paper
- C3
- open access
Crosstalk between mammalian cells and the microbiome through quorum sensing peptides, influencing cancer metastasis
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- Journal Article
- A1
- open access
Heterologous screening of hybridomas for the development of broad-specific monoclonal antibodies against deoxynivalenol and its analogues
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- Journal Article
- A2
- open access
The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
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Mesenchymal stem cell secreted platelet derived growth factor exerts a pro-migratory effect on resident Cardiac Atrial appendage Stem Cells
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The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
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Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1
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- Journal Article
- A1
- open access
On-chip light sheet illumination enables diagnostic size and concentration measurements of membrane vesicles in biofluids
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Micro-particle encapsulated carcinoma-associated fibroblast (CAF) deceive and redirect disseminated cancer cells
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Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and JAK3/STAT3 signaling
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Cell aggregation assays
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Chick heart invasion assay
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- Journal Article
- A1
- open access
The HMI™ module: a new tool to study the host-microbiota interaction in the human gastrointestinal tract in vitro
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- Journal Article
- A2
- open access
Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion
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ER stress in diffuse large B cell lymphoma: GRP94 is a possible biomarker in germinal center versus activated B-cell type
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Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression
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Unraveling the mechanisms behind the enhanced MTT conversion by irradiated breast cancer cells
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Vacuolar H+ ATPase expression and activity is required for Rab27B dependent invasive growth and metastasis of breast cancer
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Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling
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Assessment of the antineoplastic potential of chalcones in animal models
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Radiation-induced myosin IIA expression stimulates collagen type I matrix reorganization
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Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer
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- Journal Article
- A1
- open access
Frondoside A suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis
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- Journal Article
- A2
- open access
Rab27B-mediated metabolic reprogramming induces secretome acidification and chemoresistance in breast cancer cells
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CAF-encapsulated mico-particels capture free cancer cells from the peritoneal fluid
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- Journal Article
- A1
- open access
The in ovo CAM-assay as a xenograft model for sarcoma
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Protein secretome analysis of evolving and responding tumor ecosystems
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Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery
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Design, synthesis and structure-activity relationships of some novel, highly potent anti-invasive (E)- and (Z)-stilbenes
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- Journal Article
- A1
- open access
Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation
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Angiopoietin-like protein 4 : health effects, modulating agents and structure-function relationships
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Persistent subretinal fluid after surgery for rhegmatogenous retinal detachment: hypothesis and review
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- Journal Article
- A1
- open access
N-Cadherin in neuroblastoma disease : expression and clinical significance