Frank Loontiens
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Base-sequence specificity of Hoechst 33258 and DAPI binding to five (A/T)(4) DNA sites with kinetic evidence for more than one high-affinity Hoechst 33258-AATT complex.
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Kinetics of binding of hoechst dyes to DNA studied by stopped-flow fluorescence techniques.
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Experimental precedent for the need to involve the primary hydration layer of DNA in lead drug design.
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Increased stability and lifetime of the complex formed between DNA and meta-phenyl-substituted Hoechst dyes as studied by fluorescence titrations and stopped-flow kinetics.
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Rational ligand design for the minor groove: testing the predictability of putative desgined binding interactions for Hoechst 33258 analogues. Ninth Conversation in the Discipline of Biomolecular Stereodynamics, June 20-24 Albany New York