Show
Sort by
-
M2e-tetramer-specific memory CD4 T cells are broadly protective against influenza infection
-
Oral delivery of Escherichia coli persistently infected with M2e-displaying bacteriophages partially protects against influenza A virus
-
Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection
-
M2-based influenza vaccines : recent advances and clinical potential
-
- Journal Article
- A1
- open access
Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies
-
Crystal structure of the conserved amino terminus of the extracellular domain of matrix protein 2 of influenza A virus gripped by an antibody
-
Comparison of the antiviral activity of Mus spretus Mx1 and Mus musculus A2G Mx1 against influenza A viruses
-
- Journal Article
- A2
- open access
M2e-based universal influenza A vaccines
-
Functional comparison of Mx1 from two different mouse species reveals the involvement of loop L4 in the antiviral activity against influenza A viruses
-
- Journal Article
- A1
- open access
Protection against influenza A virus challenge with M2e-displaying filamentous Escherichia coli phages
-
- Journal Article
- A1
- open access
A GFP expressing influenza A virus to report in vivo tropism and protection by a matrix protein 2 ectodomain-specific monoclonal antibody
-
Structure of the extracellular domain of matrix protein 2 of influenza A virus in complex with a protective monoclonal antibody
-
- Journal Article
- A1
- open access
Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein
-
Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge
-
Natural and long-lasting cellular immune responses against influenza in the M2e-immune host
-
- Journal Article
- A1
- open access
Immunogenicity of live attenuated B. pertussis BPZE1 producing the universal influenza vaccine candidate M2e
-
- Journal Article
- A1
- open access
M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A
-
Recombinant influenza virus carrying the respiratory syncytial virus (RSV) F85-93 CTL epitope reduces RSV replication in mice
-
Cutting edge approaches towards novel and cross-protective influenza vaccines
-
Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly
-
Cytokine research in Belgium
-
A novel non-toxic combined CTA1-DD and ISCOMS adjuvant vector for effective mucosal immunization against influenza virus
-
Universal vaccine based on ectodomain of matrix protein 2 of Influenza A: Fc receptors and alveolar macrophages mediate protection
-
- Journal Article
- A1
- open access
Antiserum against the conserved nine amino acid N-terminal peptide of influenza A virus matrix protein 2 is not immunoprotective
-
- Journal Article
- A1
- open access
Controlling influenza by cytotoxic T-cells : calling for help from destroyers
-
Cloning and expression of human interferon-beta: from bc to ac
-
M2e-based universal influenza A vaccine
-
Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments
-
PANDEMIC PREPAREDNESS: TOWARD A UNIVERSAL INFLUENZA VACCINE
-
Universal influenza A M2e-HBc vaccine protects against disease even in the presence of pre-existing anti-HBc antibodies
-
An influenza A vaccine based on tetrameric ectodomain of matrix protein 2
-
CTA1-M2e-DD: A novel mucosal adjuvant targeted influenza vaccine
-
- Journal Article
- A3
- open access
A universal vaccine against influenza
-
Improved design and intranasal delivery of an M2e-based human influenza A vaccine
-
Improved periplasmic production of biologically active murine interleukin-2 in Escherichia coli through a single amino acid change at the cleavage site
-
The universal influenza vaccine M2e-HBc administered intranasally in combination with the adjuvant CTA1-DD provides complete protection
-
Universal influenza A vaccine: Optimization of M2-based constructs
-
A "universal" human influenza A vaccine
-
Tumor necrosis factor-alpha augmented tumor response in B16BL6 melanoma-bearing mice treated with stealth liposomal doxorubicin (DOXIL (R)) correlates with altered DOXIL (R) pharmacokinetics
-
Characterization of the interaction between murine tumour necrosis factor and monoclonal antibodies.
-
Bioavailability of recombinant tumor necrosis factor determines its lethality in mice.
-
Spontaneous and oncogene-mediated acquisition of the invasive phenotype by cells in culture.
-
Soluble recombinant influenza vaccines
(2001) PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES. 356(1416). p.1961-1963 -
Kanker: wat brengt de toekomst?
-
Heterotrimers formed by tumor necrosis factors of different species or muteins.
-
Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants.
-
Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.
-
Expression in Escherichia coli of the death domain of the human p55 tumor necrosis factor receptor.
-
Role of reactive oxygen species in tumor necrosis factor toxicity
-
Structure/function analysis of p55 tumor necrosis factor receptor and Fas-associated death domain : effect on necrosis in L929sA cells.
-
Cloning and expression of cytokine genes
-
Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase.
-
Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential.
-
Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives.
-
Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.
-
Tumor necrosis factor-induced microtubule stabilization mediated by hyperphosphorylated oncoprotein 18 promotes cell death.
-
Redox regulation of TNF signaling.
-
Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis.
-
The proteolytic procaspase activation network: an in vitro analysis.
-
More than one way to die: apoptosis, necrosis and reactive oxygen damage.
-
An advanced vector system for high-level recombinant gene expression in Escherichia coli
-
GAL4 is a substrate for caspases : implications for two-hybrid screening and other GAL4-based assays
-
The structure of mouse tumour-necrosis factor at 1.4 angstrom resolution: towards modulation of its selectivity and trimerization.
-
The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases.
-
Identification of a locus on distal mouse chromosome 12 that controls resistance to tumor necrosis factor-induced lethal shock.
-
A universal influenza A vaccine based on the extracellular domain of the M2 protein.
-
Inhibition of Tumor Necrosis Factor-induced necrotic cell death by the zinc finger protein A20.
-
- Journal Article
- A1
- open access
The zinc finger protein A20 inhibits TNF-induced NF-kappa B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappa B-inhibiting protein ABIN.
-
The role of complement activation in tumour necrosis factor-induced lethal hepatitis.
-
Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutinin.
-
Identification of caspases that cleave presenilin-1 and presenilin-2 - Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.
-
Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: Inhibition of Cdc42-mediated filopodium formation by TNF.
-
The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region.
-
Tumor necrosis factor and lymphotoxin
-
Engineering of the carbohydrate moiety of fungal proteins to a mammalian type
-
Identification of a new caspase homologue: caspase-14.
-
Cathepsin B-mediated activation of the proinflammatory caspase-11
-
Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4(+) T cell responsiveness to antigen.
-
- Journal Article
- A1
- open access
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.
-
Cooperation of both TNF receptors in inducing apoptosis: Involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75.
-
Molecular cloning and identification of murine caspase-8.
-
An antibody which binds to the membrane-proximal end of influenza virus haemagglutinin (H3 subtype) inhibits the low-pH-induced conformational change and cell-cell fusion but does not neutralize virus.
-
Cross-talk between steroids and NF-kappa B: what language?
-
Use of the yeast three-hybrid system as a tool to study caspases.
-
Differentiation of EL4 lymphoma cells by tumoral environment is associated with inappropriate expression of the large chondroitin sulfate proteoglycan PG-M and the tumor-associated antigen HTgp-175.
-
Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity.
-
TRAF2 plays a dual role in NF-kappa B-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and I kappa B kinase pathways.
-
- Journal Article
- A1
- open access
Dual signaling of the Fas receptor: Initiation of both apoptotic and necrotic cell death pathways.
-
Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses.
-
Differential activation of phospholipases during necrosis or apoptosis: A comparative study using tumor necrosis factor and anti-Fas antibodies.
-
Evaluation of recombinant A/Victoria/3/75 (H3N2) influenza neuraminidase mutants as potential broad-spectrum subunit vaccines against influenza A.
-
Cloning and expression of a fused gene encoding TNFRI death domain and chloramphenicol acetyltransferase.
-
Regulation of microsomal triglyceride transfer protein mRNA expression by endotoxin and cytokines.
-
Functional display of a heterologous protein on the surface of Lactococcus lactis by means of the cell wall anchor of Staphylococcus aureus protein A
-
pH-dependent aggregation and secretion of soluble monomeric influenza hemagglutinin.
-
- Journal Article
- A1
- open access
Autocrine tumor necrosis factor (TNF) and lymphotoxin (LT) alpha differentially modulate cellular sensitivity to TNF/LT-alpha cytotoxicity in L929 cells.
-
Induction of unresponsiveness to tumor necrosis factor (TNF) after autocrine TNF expression requires TNF membrane retention.
-
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor kappa B p65 transactivation mediated by tumor necrosis factor.
-
Efficient secretion of biologically active recombinant OB protein (leptin) in Escherichia coli, purification from the periplasm and characterization.
-
High-level constitutive expression of alpha(1)-acid glycoprotein and lack of protection against tumor necrosis factor-induced lethal shock in transgenic mice.
-
In vitro conversion of the conversion of the carbohydrate moiety of fungal glycoproteins to mammalian-type oligosaccharides. Evidence for iV-acetylglucosaminyltransferase-I-accepting glycans from Trichoderma reesei
-
Tumour necrosis factor: intracellular mechanism of action
-
al-Acid glycoprotein and al-antitrypsin inhibit TNF-induced but not anti-Fas-induced apoptosis of hepatocytes in mice
-
Structural characterization of N-linked oligosaccharides from cellobiohydrolase I secreted by the filamentous fungus Trichoderma reesei RUTC30
-
Glucocorticoid-mediated repression of nuclear factor-κB-dependent transcription involves direct interference with transactivation
(1997) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 94(25). p.13504-13509 -
Characterization of seven murine caspase family members
-
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells.
-
Recombination signal sequence binding protein J kappa is constitutively bound to the NF-kappa B site of the interleukin-6 promoter and acts as a negative regulatory factor.
-
Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma.
-
alpha(1)-acid glycoprotein and alpha(1)-antitrypsin inhibit TNF-induced but not anti-Fas-induced apoptosis of hepatocytes in mice.
-
A20 inhibits NF-kappa B activation independently of binding to 14-3-3 proteins.
-
Cleavage of caspase family members by granzyme B: A comparative study in vitro.
-
A radioactive assay for sialyltransferase activity using 96-well multiscreen filtration plates.
-
Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawal.
-
- Journal Article
- A1
- open access
Induced expression of trimerized intracellular domains of the human tumor necrosis factor (TNF) p55 receptor elicits TNF effects.
-
Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria.
-
Cell death induction by receptors of the TNF family: Towards a molecular understanding.
-
Resistance to tumor necrosis factor (TNF) cytotoxicity by autocrine TNF production is independent of intracellular signaling pathways.
-
In vitro conversion of the carbohydrate moiety of fungal glycoproteins to mammalian-type oligosaccharides - Evidence for N-acetylglucosaminyltransferase-I-accepting glycans from Trichoderma reesei.
-
Protection of mice against a lethal influenza challenge by immunization with yeast-derived recombinant influenza neuraminidase.
-
Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor.
-
Crystallization and preliminary X-ray studies of mouse tumor necrosis factor.
-
Expression of human and murine interleukins in Lactococcus lactis
-
al-Antitrypsin inhibits the lethal response to TNF in mice
-
Tumour growth results in changes in placental amino acid transport in the rat: A tumour necrosis factor alpha-mediated effect.
-
A20, an inhibitor of cell death, self-associates by its zinc finger domain.
-
TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.
-
Inhibition of and sensitization to the lethal effects of tumor necrosis factor
-
alpha(1)-antitrypsin inhibits the lethal response to TNF in mice.
-
TNF receptor p55 plays a major role in centrally mediated increases of serum IL-6 and corticosterone after intracerebroventricular injection of TNF.
-
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumour necrosis factor.
-
The expression of the Photinus pyralis luciferase gene in Staphylococcus aureus Cowan I allows the development of a live amplifiable tool for immunodetection.
-
Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: Functional analysis of the tumor necrosis factor receptors.
-
Abnormal glutathione and sulfate levels after interleukin 6 treatment and in tumor-induced cachexia.
-
Recombinant neuraminidase vaccine protects against lethal influenza.
-
ESM-1 is a novel human endothelial cell-specific molecule expressed in lung and regulated by cytokines.
-
Murine IL-12 is involved in Calmette-Guerin Bacillus-induced sensitization and is by itself sufficient to sensitize mice to the lethal effects of human TNF.
-
Molecular and immunological characterization of soluble aggregated A/Victoria/3/75 (H3N2) influenza haemagglutinin expressed in insect cells.
-
Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) production during murine endotoxaemia.
-
Functional characterization of the prodomain of interleukin-1 beta-converting enzyme.
-
Increased stability of phage T7g10 mRNA is mediated by either a 5'- or a 3'-terminal stem-loop structure.
-
Tumor necrosis factor and the systemic inflammatory response syndrome.
-
The oxidative metabolism of glutamine - A modulator of reactive oxygen intermediate-mediated cytotoxicity of tumor necrosis factor in L929 fibrosarcoma cells.
-
Platelet-activating factor is a mediator in tumor necrosis factor galactosamine-induced lethality.
-
Cloning and expression of cytokine genes
-
Biologic therapy with TNF: preclinical studies
-
TNF-induced mechanisms for IL6 gene induction
-
Optimalization and application in TNF-related models of a method to estimate NO production in vivo.
-
Two tumour necrosis factor receptors : structure and function
-
Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells
-
Production in Escherichia coli of a functional murine and murine::human chimeric F(ab')2 fragment and mature antibody directed against human placental alkaline phosphatase
-
Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour-necrosis-factor (TNF) receptor is mediated by endogenous murine TNF.
-
Detailed analysis of the IL-5-IL-5Ra interaction - Characterization of crucial residues on the ligand and the receptor.
-
PRODUCTION OF SOLUBLE AND ACTIVE RECOMBINANT MURINE INTERLEUKIN-2 IN ESCHERICHIA-COLI - HIGH-LEVEL EXPRESSION, KIL-INDUCED RELEASE, AND PURIFICATION.
-
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity.
(1995) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 92(18). p.8115-8119 -
Characterization of critical residues in the cytoplasmic domain of the human interleukin-5 receptor a chain required for growth signal-transduction.
-
Generation and biological characterization of membrane-bound, uncleavable murine tumor-necrosis factor.
-
TNF-R55-SPECIFIC FORM OF HUMAN TUMOR-NECROSIS-FACTOR-ALPHA INDUCES COLLAGENASE GENE-EXPRESSION BY HUMAN SKIN FIBROBLASTS.
-
2 TUMOR-NECROSIS-FACTOR RECEPTORS - STRUCTURE AND FUNCTION.
-
Casein kinase-1 phosphorylates the p75 tumor-necrosis-factor receptor and negatively regulates tumor-necrosis-factor signaling for apoptosis.
-
A FAIRLY CONSERVED EPITOPE ON THE HEMAGGLUTININ OF INFLUENZA-A (H3N2) VIRUS WITH VARIABLE ACCESSIBILITY TO NEUTRALIZING ANTIBODY.
-
VERSATILE, MULTI-FEATURED PLASMIDS FOR HIGH-LEVEL EXPRESSION OF HETEROLOGOUS GENES IN ESCHERICHIA-COLI - OVERPRODUCTION OF HUMAN AND MURINE CYTOKINES.
-
REQUIREMENT OF AN ICE/CED-3 PROTEASE FOR FAS/APO-1-MEDIATED APOPTOSIS.
-
ENGINEERING OF THE CARBOHYDRATE MOIETY OF FUNGAL GLYCOPROTEINS TO A MAMMALIAN TYPE.
-
Mechanism of tolerance to tumor-necrosis-factor - Receptor-specific pathway and selectivity.
(1995) AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 38(2) R398-R405). -
Dimerization of chimeric erythropoietin 75 kDa tumour-necrosis-factor (TNF) receptors transduces TNF signals - Necessity for the 75 kDa TNF-receptor transmembrane domain.
-
SIMULTANEOUS LIGHT-EMISSION FROM CLONED VIBRIO-FISCHERI LUX GENES AND EXPRESSION OF LAMB OR LAMB PROTEIN-A FUSION PROTEINS IN ESCHERICHIA-COLI DEPENDS ON USING A SINGLE CHIMERIC OPERON.
-
PIONEERING WORK.
-
POLAR AGENTS WITH DIFFERENTIATION-INDUCING CAPACITY POTENTIATE TUMOR NECROSIS FACTOR-MEDIATED CYTOTOXICITY IN HUMAN MYELOID CELL-LINES.
-
SECRETION OF BIOLOGICALLY-ACTIVE MURINE INTERLEUKIN-2 BY LACTOCOCCUS-LACTIS SUBSP LACTIS.
-
TIGHT TRANSCRIPTIONAL CONTROL MECHANISM ENSURES STABLE HIGH-LEVEL EXPRESSION FROM T7 PROMOTER-BASED EXPRESSION PLASMIDS.
-
BOTH TNF RECEPTORS ARE REQUIRED FOR TNF-MEDIATED INDUCTION OF APOPTOSIS IN PC60 CELLS.
-
Anti-tumor activity of tumor necrosis factor in combination with interferon-gamma is not affected by prior tolerization.
-
Involvement of IFN-γ in Bacillus Calmette-Guérin-induced but not in tumor-induced sensitization to TNF-induced lethality
-
The two genes encoding yeast ribosomal protein S8 reside on different chromosomes, and are closely linked to the hsp7O stress protein genes SSA3 and SSA4.
-
FUNCTIONAL REQUIREMENT OF THE 2 TNF RECEPTORS FOR INDUCTION OF APOPTOSIS IN PC60 CELLS AND THE ROLE OF MITOCHONDRIA IN TNF-INDUCED CYTOTOXICITY.
-
Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor.
-
Production of enzymatically active-rat protein disulfide-isomerase in Escherichia-coli.
-
Molecular mechanisms of tumor necrosis factor-induced cytotoxicity - What we do understand and what we do not.
-
Recombinant IL-1 receptor antagonist protects against TNF-induced lethality in mice.
-
Mechanism of induction of tolerance to tumour-necrosis-factor (TNF): No involvement of modulators of TNF bioavailability or receptor-binding.
-
DISSOCIATION OF TNF-ALPHA CYTOTOXIC AND PROINFLAMMATORY ACTIVITIES BY P55 RECEPTOR-SELECTIVE AND P75 RECEPTOR-SELECTIVE TNF-ALPHA MUTANTS.
-
Response of interleukin-6-deficient mice to tumor necrosis factor-induced metabolic changes and lethality.
-
- Journal Article
- A1
- open access
Protection by alpha(1)-acid glycoprotein against tumor necrosis factor-induced lethality.
-
A BIFUNCTIONAL MURINE = HUMAN CHIMERIC ANTIBODY WITH ONE ANTIGEN-BINDING ARM REPLACED BY BACTERIAL BETA-LACTAMASE.
-
Modulation of the release of cytokines and reduction of the shock syndrome induced by anti-CD3 monoclonal-antibody in mice by interleukin-10.
-
Studies on the induction of the interleukin-6 promoter in cell lines of human and simian origin.
-
THE 2 GENES ENCODING YEAST RIBOSOMAL-PROTEIN S8 RESIDE ON DIFFERENT CHROMOSOMES, AND ARE CLOSELY LINKED TO THE HSP70 STRESS PROTEIN GENE-SSA3 AND GENE-SSA4.
-
Efficient specific release of periplasmic proteins from Escherichia coli using temperature induction of cloned kil gene of pMB9.
-
Human interferon-beta, expressed in Saccharomyces cerevisiae, is predominantly directed to the vacuoles. Influence of modified co-expression of secretion factors and chaperones
-
Structure-activity studies of human tumour necrosis factors.
-
Receptor-selective mutants of tumour necrosis factor in the therapy of cancer : preclinical studies
-
Strategies to broaden the therapeutic margin of tumor necrosis factor
-
A new method for purification of influenza neuraminidase released by pronase digestion.
-
Production of enzymatically active rat protein disulfide isomerase in COS-1 cells.
-
Tumour necrosis factor
-
Two pathways of tumor necrosis factor signal transduction: in vitro and in vivo implications
-
Tumor necrosis factor: molecular and cellular biology and clinical relevance
(1993) -
Construction of a mouse and a mouse-human chimeric immunotoxin on the genetic level and production of functional protein in E. coli
-
Expression, purification and crystallization of fully active, glycosylated human interleukin-5
-
Protection against tumor necrosis factor-induced lethality
-
T7-RNA-polymerase terminates at poly-A regions on plasmids.
-
Translational coupling: the importance of the translational efficiency of the first cistron.
-
Functional exposition of streptavidin at the surface of Escherichia coli using the IgAß domain of the IgA protease of Neisseria gonorrhoea.
-
Increase of the soluble fraction of human interferon-y expressed in Escherichia coli, due to the chaperonin activity of GroEL/ES.
-
Studies on the inducibility of the IL6 promoter using a reporter gene construction.
-
Tumor necrosis factor cytotoxicity is associated with activation of cellular phospholipases
-
Folding of the MS2 coat protein in Escherichia coli is modulated by translational pauses resulting from mRNA secondary structure and codon usage : a hypothesis
-
Recombinant secreted haemagglutinin protects mice against a lethal challenge of influenza virus
-
HUMAN TNF MUTANTS WITH SELECTIVE ACTIVITY ON THE P55 RECEPTOR.
-
Effect of bcl-2-proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity.
-
Pap pili as a vector system for surface exposition of an immunoglobulin G-binding domain of protein-A of Staphylococcus-aureus in Escherichia-coli.
-
TUMOR-NECROSIS-FACTOR ACTIVATES HUMAN ENDOTHELIAL-CELLS THROUGH THE P55-TUMOR NECROSIS FACTOR-RECEPTOR BUT THE P75-RECEPTOR CONTRIBUTES TO ACTIVATION AT LOW TUMOR-NECROSIS-FACTOR CONCENTRATION.
-
ENHANCEMENT OF TUMOR-NECROSIS-FACTOR CYTOTOXICITY BY LITHIUM-CHLORIDE IS ASSOCIATED WITH INCREASED INOSITOL PHOSPHATE ACCUMULATION.
-
INCREASED IL-6 PRODUCTION AND IL-6-MEDIATED IG SECRETION IN MURINE HOST-VS-GRAFT DISEASE.
-
CELL-MEMBRANE PERMEABILIZATION AND CELLULAR COLLAPSE, FOLLOWED BY LOSS OF DEHYDROGENASE-ACTIVITY - EARLY EVENTS IN TUMOR NECROSIS FACTOR-INDUCED CYTOTOXICITY.
-
ACTIVATION OF THE NUCLEAR FACTOR-KAPPA-B IS NOT SUFFICIENT FOR REGULATION OF TUMOR NECROSIS FACTOR-INDUCED INTERLEUKIN-6 GENE-EXPRESSION.
-
Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.
-
Cyclooxygenase inhibitors prevent the induction of tolerance to the toxic effects of tumor necrosis factor.
-
TUMOR-NECROSIS-FACTOR, ITS RECEPTORS AND THE CONNECTION WITH INTERLEUKIN-1 AND INTERLEUKIN-6.
-
HIGH-LEVEL EXPRESSION, PURIFICATION, AND RENATURATION OF RECOMBINANT MURINE INTERLEUKIN-2 FROM ESCHERICHIA-COLI
-
- Journal Article
- A1
- open access
INTERLEUKIN-10 REDUCES THE RELEASE OF TUMOR-NECROSIS-FACTOR AND PREVENTS LETHALITY IN EXPERIMENTAL ENDOTOXEMIA.
-
LamB as a carrier molecule for the functional exposition of IgG-binding domains of the Staphylococcus aureus protein A at the surface of Escherichia coli K12.
-
Phenotypic effects in Saccharomyces cerevisiae after regulated expression of beta-(l,3)-glucanase from Nicotiana plumbaginifolia
-
TUMOR-NECROSIS-FACTOR CYTOTOXICITY IS ASSOCIATED WITH PHOSPHOLIPASE-D ACTIVATION.
-
Sensitization of tumor cells to tumor necrosis factor action by the protein kinase inhibitor staurosporine
-
Tumor-necrosis-factor : mechanism of action at the molecular, cellular and in vivo level
-
Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma
-
Organization and chromosomal localization of the human interleukin 5 receptor cc-chain gene
-
Potentiation of tumour necrosis factor-mediated activities by lithium salts: a review
-
Limited involvement of interleukin-6 in the pathogenesis of lethal septic shock as revealed by the effect of monoclonal antibodies against interleukin-6 or its receptor in various murine models
-
TNF-mediated IL6 gene expression and cytotoxicity are co-inducible in TNF resistant L929 cells
-
Synergistic induction of interleukin-6 by tumor necrosis factor and lithium chloride in mice: Possible role in the triggering and exacerbation of psoriasis by lithium treatment.
-
Expression of an exogenous tumor-necrosis-factor (TNF) gene in TNF-sensitive cell-lines confers resistance to TNF-mediated cell-lysis.
-
Cloning and expression of the canine interferon-gamma gene.
-
Disulphide bridge formation in the periplasm of Escherichia-coli: betalactamase: human IgG3 hinge fusions as a model system.
-
Selective species specificity of tumor-necrosis-factor for toxicity in the mouse.
-
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.
-
Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis.
-
Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin-5 receptor alpha-subunit.
(1992) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 89(15). p.7041-7045 -
COLEY VACCINE AND TNF THERAPY.
-
TUMOR-NECROSIS-FACTOR STIMULATES MULTIPLE SERINE THREONINE PROTEIN-KINASES IN SWISS 3T3 AND L929 CELLS - IMPLICATION OF CASEIN KINASE-2 AND EXTRACELLULAR SIGNAL-REGULATED KINASES IN THE TUMOR-NECROSIS-FACTOR SIGNAL TRANSDUCTION PATHWAY.
-
Efficient synthesis of secreted murine interleukin-2 by Saccharomyces cerevisiae: Influence of 3'-untranslated regions and codon usage.
-
The glucocorticoid antagonist RU38486 mimics inicrleukin-1 in its sensitization to the lethal and interleukin-6-inducing properties of tumor-necrosis-factor.
-
Production of functionally active murine and murine::human chimeric F(ab')2 fragments in COS-1 cells.
-
The invasion suppressor role of E-cadherin
(1992) Metastasis : basic research and its clinical applications. In Contributions to Oncology 44. p.108-126 -
The influence of modulating substances on tumor necrosis factor and interleukin-6 levels after injection of murine tumor necrosis factor or lipopolysaccharide in mice
-
Molecular basis of a high affinity murine interleukin-5 receptor
-
Tumor necrosis factor: characterization at the molecular, cellular and in vivo level
-
Lithium chloride potentiates tumor necrosis factor-induced and interleukin 1-induced cytokine and cytokine receptor expression